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pro vyhledávání: '"Werner H. Bomann"'
Autor:
Christian Strupp, Nicolas Quesnot, Céline Weber-Parmentier, Lysiane Richert, Werner H. Bomann, Pramila Singh
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 117
Benfluralin is an herbicide of the dinitroaniline class used to control grasses and weeds. In a 2 year dietary study in rats, benfluralin increased incidences of thyroid follicular adenoma and carcinoma at high dietary concentrations (≥2500 ppm). T
Autor:
Michael Battalora, Werner H. Bomann, M. Aggarwal, Richard C. Peffer, Matthew J. LeBaron, Helen Tinwell, Christoph Werner, Rocky R. Rowe
Publikováno v:
Regulatory Toxicology and Pharmacology. 96:106-120
Methods for investigating the Mode of Action (MoA) for rodent liver tumors via constitutive androstane receptor (CAR) activation are outlined here, based on current scientific knowledge about CAR and feedback from regulatory agencies globally. The ke