Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Werner Coussement"'
Autor:
Loeckie De Zwart, Johan Monbaliu, Tony Greway, Vera Hillewaert, Liesbeth Ceelen, Marieke Voets, Werner Coussement, Greet Teuns
Publikováno v:
The American journal of forensic medicine and pathology. 33(2)
Postmortem redistribution of fentanyl in the rabbit was investigated after application of the 50-μg/h Durogesic pain patch. Patches were applied for 48 hours. Two cycles of patch administration were used before characterization of the postmortem red
Publikováno v:
Annali dell'Istituto superiore di sanita. 44(4)
Compliance with the Organisation for Economic Co-operation and Development (OECD) principles of good laboratory practice (GLP) is discussed in particular as regards the responsibility of the management of a test facility (TF) when performing a monosi
Autor:
L. Lammens, Werner Coussement, Marie-Paule Bouche, Sandra De Jonghe, Sophie Lachau-Durand, B. Willems, Johan Verbeeck, Sofie Starckx, Petra Vinken
Publikováno v:
Toxicologic pathology. 36(2)
Dietary dosing of the non-nucleoside reverse transcriptase inhibitor (NNRTI) TMC125, under development for treatment of HIV-1, resulted in a syndrome in male mice in a previous experiment that was termed hemorrhagic cardiomyopathy. In literature, thi
Autor:
Timothy P. Coogan, Graham P. Bailey, Loeckie de Zwart, L. Lammens, Luc De Schaepdrijver, Araz Raoof, Marie-Claude Rouan, Johan Monbaliu, Werner Coussement
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 26(1)
With the growing experience in the conduct of juvenile toxicity studies for multiple classes of compound, the 'case-by-case' approach has become under much more pressure. Instead, a general screen or 'standard design' is now commonly expected by regu
Autor:
Johan Monbaliu, Ilse Van den Wyngaert, Loeckie de Zwart, Luc De Schaepdrijver, Geert Mannens, Martijn Scholten, Werner Coussement, Graham P. Bailey, Jos M. Van Houdt, Timothy P. Coogan, Pieter Annaert
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 26(3-4)
Knowledge of the ontogeny of the various systems involved in distribution and elimination of drugs is important for adequate interpretation of the findings during safety studies in juvenile animals. The present study was designed to collect informati
Autor:
Roel Straetemans, Petra Vinken, Miek Desmidt, Geert Molenberghs, Nick Goeminne, Werner Coussement, Luc Bijnens, Ziv Shkedy, Bob Van Den Poel
During preclinical drug development, the immune system is specifically evaluated after prolonged treatment with drug candidates, because the immune system may be an important target system. The response of antibodies against a T-cell-dependent antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619a6e2a409b2c337160eeaebb1b24ff
http://hdl.handle.net/1942/2037
http://hdl.handle.net/1942/2037
Autor:
J. Fransen, Charles Wang, Graham P. Bailey, Werner Coussement, Luc De Schaepdrijver, Kathleen Van den Bulck
Publikováno v:
Reproductive Toxicology. 24:69-70
Publikováno v:
The Journal of Parasitology. 74:931
Diclazuril, a new benzeneacetonitrile anticoccidial, has potent activity against various stages of Eimeria tenella. A single treatment of experimentally infected chickens during the prepatent phase (up to day 5) results in a complete interruption of