Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Werner C. Jaeger"'
1
Ventriculoperitoneal shunts in neonates: a retrospective study of outcomes with antibiotic-impregnated catheters and a modified peri-operative antibiotic protocol
Autor: Shripada Rao, Deepa Vineet, Werner C. Jaeger, Sharon X. Lee, Nitesh Agarwal, Anthony D. Keil
Publikováno v: British Journal of Neurosurgery. 31:672-676
CSF infection is a significant complication of ventriculoperitoneal (VP) shunts and results in prolonged hospital stay, developmental delay and decreased quality of life. To decrease the high rates of neonatal VP shunt infections, an updated clinical
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bac52179a7f96012788897f6dc93ddc
https://doi.org/10.1080/02688697.2017.1368450
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2
Identification and profiling of CXCR3-CXCR4 chemokine receptor heteromer complexes
Autor: Werner C. Jaeger, Rob Leurs, Ruth M. Seeber, Martine J. Smit, Hendrikus Boddeke, M. M. H van Lipzig, Jonathan Vinet, Anne O. Watts, Kevin D. G. Pfleger, M. van Zwam, M. M. C van der Lee, Henry F. Vischer, G.J.R. Zaman, Marco Siderius
Publikováno v: British Journal of Pharmacology. 168:1662-1674
BACKGROUND AND PURPOSE The C-X-C chemokine receptors 3 (CXCR3) and C-X-C chemokine receptors 4 (CXCR4) are involved in various autoimmune diseases and cancers. Small antagonists have previously been shown to cross-inhibit chemokine binding to CXCR4,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bda692355ccd7dfa6c86ee95a0e722cb
https://doi.org/10.1111/bph.12064
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3
G protein-coupled receptor heteromers
Autor: Kevin D. G. Pfleger, Werner C. Jaeger, Lakshmi A. Devi, Ivone Gomes, Wakako Fujita, Mohammed Akli Ayoub
Publikováno v: Annual Review of Pharmacology and Toxicology
Annual Review of Pharmacology and Toxicology, Annual Reviews, 2016, 56 (1), pp.403-425. ⟨10.1146/annurev-pharmtox-011613-135952⟩
G protein–coupled receptors (GPCRs) compose one of the largest families of membrane proteins involved in intracellular signaling. They are involved in numerous physiological and pathological processes and are prime candidates for drug development.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c678f6e27317a71f0605bfb068de1ff6
https://hal.archives-ouvertes.fr/hal-01353287
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4
Molecular determinants of orexin receptor-arrestin-ubiquitin complex formation
Autor: Karin A. Eidne, Kevin D. G. Pfleger, Werner C. Jaeger, Ruth M. Seeber
Publikováno v: British Journal of Pharmacology
Background and Purpose The orexin system regulates a multitude of key physiological processes, particularly involving maintenance of metabolic homeostasis. Consequently, there is considerable potential for pharmaceutical development for the treatment
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1587919a7b61695d259ec54b4d215221
https://pubmed.ncbi.nlm.nih.gov/24206104
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5
Temporal profiling of orexin receptor-arrestin-ubiquitin complexes reveals differences between receptor subtypes
Autor: Werner C. Jaeger, Kevin D. G. Pfleger, Karin A. Eidne, Matthew B. Dalrymple
Publikováno v: The Journal of Biological Chemistry
Orexin G protein-coupled receptors (OxRs) and their cognate agonists have been implicated in a number of disorders since their recent discovery, ranging from narcolepsy to formation of addictive behavior. Bioluminescence resonance energy transfer ass
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e13831a05f42a8f07531ecba282555
https://pubmed.ncbi.nlm.nih.gov/21378163
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