Hydrogen/deuterium exchange memory NMR reveals structural epitopes involved in IgE cross-reactivity of allergenic lipid transfer proteins

Autor: Michael Hauser, Christof Regl, Werner Auzinger, Danila Zennaro, Peter Lackner, Sabrina Wildner, Christian G. Huber, Eva Vejvar, Sara Huber, Gabriele Gadermaier, Nicole Wopfer, Ronald van Ree, Josef Laimer, Martina Di Muzio, Adriano Mari, Fatima Ferreira, Mario Schubert

Publikováno v: J Biol Chem
Journal of biological chemistry, 295(51), 17398-17410. American Society for Biochemistry and Molecular Biology Inc.

Identification of antibody-binding epitopes is crucial to understand immunological mechanisms. It is of particular interest for allergenic proteins with high cross-reactivity as observed in the lipid transfer protein (LTP) syndrome, which is characte

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