Výsledky vyhledávání - "Wern Cui, Chu"

Akademický článek

BCG-Induced Trained Immunity in Healthy Individuals: The Effect of Plasma Muramyl Dipeptide Concentrations

Autor: Vera P. Mourits, Valerie A. C. M. Koeken, L. Charlotte J. de Bree, Simone J. C. F. M. Moorlag, Wern Cui Chu, Xiaoli Xu, Helga Dijkstra, Heidi Lemmers, Leo A. B. Joosten, Yue Wang, Reinout van Crevel, Mihai G. Netea

Publikováno v: Journal of Immunology Research, Vol 2020 (2020)

BCG vaccination protects not only against tuberculosis but also against heterologous infections. This effect differs between individuals, yet the factors responsible for this variation are unknown. BCG-induced nonspecific protection is, at least part

Externí odkaz: https://doaj.org/article/58896731c6ec463baa60fcef2646f1d7

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Viral proteases activate the CARD8 inflammasome in the human cardiovascular system

Autor: Rhea Nadkarni, Wern Cui Chu, Cheryl Q.E. Lee, Yasir Mohamud, Lynn Yap, Gee Ann Toh, Sheryl Beh, Radiance Lim, Yiyun Michelle Fan, Yizhuo Lyanne Zhang, Kim Robinson, Karl Tryggvason, Honglin Luo, Franklin Zhong, Lena Ho

Publikováno v: Journal of Experimental Medicine. 219

Nucleotide-binding oligomerization domain (NBD), leucine-rich repeat (LRR) containing protein family (NLRs) are intracellular pattern recognition receptors that mediate innate immunity against infections. The endothelium is the first line of defense

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08bae07de3fed3534fa67f1a79b2a12d
https://doi.org/10.1084/jem.20212117

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Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity

Autor: Kong-Peng Lam, Wern Cui Chu, Jianhe Wang, Leo A. B. Joosten, Haishan Wang, Khai Pang Leong, Norman Pavelka, Yuan Qiao, Yue Wang, Fabien Cottier, Marije Oosting, Xiaoli Xu, Zhen-Xing Huang, Shengli Xu, Louis Yi Ann Chai, Mihai G. Netea, Sven Pettersson, Carol Ng, Parag Kundu

Publikováno v: Nature Microbiology, 4, 766-773
Nature Microbiology, 4, 5, pp. 766-773

The human microbiota provides tonic signals that calibrate the host immune response1,2, but their identity is unknown. Bacterial peptidoglycan (PGN) subunits are likely candidates since they are well-known immunity-enhancing adjuvants, released by mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308d427e955cc6fe5a6b3cd7b75710d6
https://doi.org/10.1038/s41564-019-0381-1

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Akademický článek

Human mesenchymal stem cell-derived exosomes promote orderly cartilage regeneration in an immunocompetent rat osteochondral defect model

Autor: Shipin Zhang, Keng Lin Wong, Wern Cui Chu, Ruenn Chai Lai, James Hoi Po Hui, Eng Hin Lee, Sai Kiang Lim, Wei Seong Toh

Publikováno v: Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology, Vol 6, Iss C, p 69 (2016)

Externí odkaz: https://doaj.org/article/54310222ca574829af5a13101a3b44ad

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Distribution of pericellular matrix molecules in the temporomandibular joint and their chondroprotective effects against inflammation

Autor: Wern Cui Chu, Timothy J Sng, Yu Jie Ong, Shipin Zhang, Wen-Li Tan, Vivien Y Ang, Casper Bindzus Foldager, Wei Seong Toh

Publikováno v: Chu, W C, Zhang, S, Sng, T J, Ong, Y J, Tan, W-L, Ang, V Y, Foldager, C B & Toh, W S 2017, ' Distribution of pericellular matrix molecules in the temporomandibular joint and their chondroprotective effects against inflammation ', International Journal of Oral Science, vol. 9, no. 1, pp. 43-52 . https://doi.org/10.1038/ijos.2016.57
International Journal of Oral Science

The objectives of this study were to (1) determine the distribution and synthesis of pericellular matrix (PCM) molecules (collagen VI, collagen IV and laminin) in rat temporomandibular joint (TMJ) and (2) investigate the effects of PCM molecules on c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c572b2e0b31cff4d6d81af0bcd77477
https://doi.org/10.1038/ijos.2016.57

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BCG-Induced Trained Immunity in Healthy Individuals: The Effect of Plasma Muramyl Dipeptide Concentrations

Autor: Mihai G. Netea, Reinout van Crevel, Valerie A. C. M. Koeken, Vera P. Mourits, Wern Cui Chu, Leo A. B. Joosten, L. Charlotte J. de Bree, Yue Wang, Helga Dijkstra, Simone J.C.F.M. Moorlag, Xiaoli Xu, Heidi Lemmers

Publikováno v: Journal of Immunology Research, 2020
Journal of Immunology Research
Mourits, V P, Koeken, V A C M, De Bree, L C J, Moorlag, S J C F M, Chu, W C, Xu, X, Dijkstra, H, Lemmers, H, Joosten, L A B, Wang, Y, Van Crevel, R & Netea, M G 2020, ' BCG-Induced Trained Immunity in Healthy Individuals : The Effect of Plasma Muramyl Dipeptide Concentrations ', Journal of Immunology Research, vol. 2020, 5812743 . https://doi.org/10.1155/2020/5812743
Journal of Immunology Research, Vol 2020 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8897032b439992c4ed885e6f8309be77
https://hdl.handle.net/2066/221434

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Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration

Autor: James Hoi Po Hui, Wei Seong Toh, Ruenn Chai Lai, Wern Cui Chu, Shipin Zhang, Sai Kiang Lim

Publikováno v: Osteoarthritis and Cartilage. 24(12):2135-2140

Summary Objective Clinical and animal studies have demonstrated the efficacy of mesenchymal stem cell (MSC) therapies in cartilage repair. As the efficacy of many MSC-based therapies has been attributed to paracrine secretion, particularly extracellu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07fcdadec0d147e4306d383ab2b5ee20

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