Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Weria Pezeshkian"'
Autor:
Weria Pezeshkian, John H. Ipsen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract We present FreeDTS software for performing computational research on biomembranes at the mesoscale. In this software, a membrane is represented by a dynamically triangulated surface equipped with vertex-based inclusions to integrate the effe
Externí odkaz:
https://doaj.org/article/05f8a7ba61d3428ea3d7c3049b043bc4
Autor:
Senthil Arumugam, Stefanie Schmieder, Weria Pezeshkian, Ulrike Becken, Christian Wunder, Dan Chinnapen, John Hjort Ipsen, Anne K. Kenworthy, Wayne Lencer, Satyajit Mayor, Ludger Johannes
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Gangliosides such as GM1 present in the outer leaflet of the plasma membrane of eukaryotic cells are essential for many cellular functions and pathogenic interactions. Here the authors show that the acyl chain structure of GM1 determines the establis
Externí odkaz:
https://doaj.org/article/41a538c93c3c48b9859f96ed5bb6999e
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Computer simulations of large-scale changes in membrane shape are challenging since they occur across a wide range of spatiotemporal scales. Here, authors present a multiscale algorithm that backmaps a continuum membrane model represented as a dynami
Externí odkaz:
https://doaj.org/article/c56f67a2bf8f4ce9b0a23fb2e03f8967
Publikováno v:
Toxins, Vol 13, Iss 7, p 449 (2021)
Many bacteria secrete toxic protein complexes that modify and disrupt essential processes in the infected cell that can lead to cell death. To conduct their action, these toxins often need to cross the cell membrane and reach a specific substrate ins
Externí odkaz:
https://doaj.org/article/5e5bf6215cca4d58957ed51c545c955b
Autor:
Theresa Louise Boye, Kenji Maeda, Weria Pezeshkian, Stine Lauritzen Sønder, Swantje Christin Haeger, Volker Gerke, Adam Cohen Simonsen, Jesper Nylandsted
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
The role of annexins in cell membrane repair is largely undefined. Here the authors use a model lipid bilayer to show that annexin A4 induces curvature at the membrane free edge and annexin A6 induces constriction force, and find that both annexins a
Externí odkaz:
https://doaj.org/article/35ba979e75e6437e87c4c03e0402bae3
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
We present a multi-scale simulation procedure to describe membrane-related biological processes that span over a wide range of length scales. At macroscopic length-scale, a membrane is described as a flexible thin film modeled by a dynamic triangulat
Externí odkaz:
https://doaj.org/article/e23b3dff5b054ed0aefe5092c02cc694
Publikováno v:
Ruhoff, V T, Bendix, P M & Pezeshkian, W 2023, ' Close, but not too close : a mesoscopic description of (a)symmetry and membrane shaping mechanisms ', Emerging topics in life sciences, vol. 7, no. 1, pp. 81-93 . https://doi.org/10.1042/etls20220078
Biomembranes are fundamental to our understanding of the cell, the basic building block of all life. An intriguing aspect of membranes is their ability to assume a variety of shapes, which is crucial for cell function. Here, we review various membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c3577058be191f158c5d6e2a9d1e84
https://doi.org/10.1042/etls20220078
https://doi.org/10.1042/etls20220078
Publikováno v:
Ruhoff, V T, Moreno-Pescador, G, Pezeshkian, W & Bendix, P M 2022, ' Strength in numbers : effect of protein crowding on the shape of cell membranes ', Biochemical Society Transactions, vol. 50, no. 5, pp. 1257-1267 . https://doi.org/10.1042/BST20210883
Continuous reshaping of the plasma membrane into pleomorphic shapes is critical for a plethora of cellular functions. How the cell carries out this enigmatic control of membrane remodeling has remained an active research field for decades and several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b31cdc1f83a6735cf6a2971100d6ca1
https://doi.org/10.1042/bst20210883
https://doi.org/10.1042/bst20210883
Autor:
Weria Pezeshkian, John H. Ipsen
We present FreeDTS software for performing computational research on biomembranes at the mesoscale. In this model, a membrane is represented by a dynamically triangulated surface equipped with vertex-based inclusions to integrate the effects of integ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49fbf5d52236782bebf8066926aade4b
https://doi.org/10.1101/2023.05.05.539540
https://doi.org/10.1101/2023.05.05.539540
Autor:
Anna L. Duncan, Weria Pezeshkian
Publikováno v:
Duncan, A L & Pezeshkian, W 2023, ' Mesoscale simulations : An indispensable approach to understand biomembranes ', Biophysical Journal, vol. 122, no. 11, pp. 1883-1889 . https://doi.org/10.1016/j.bpj.2023.02.017
Computer simulation techniques form a versatile tool, a computational microscope, for exploring biological processes. This tool has been particularly effective in exploring different features of biological membranes. In recent years, thanks to elegan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d7169a5b056ccd35c6f53bee607a787
https://doi.org/10.1016/j.bpj.2023.02.017
https://doi.org/10.1016/j.bpj.2023.02.017