Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Werawath Mahatthanatrakul"'
Autor:
Malinee Wongnawa, Putthaporn Kaewmeesri, Somchai Sriwiriyajan, Werawath Mahatthanatrakul, Wibool Ridtitid
Publikováno v:
Songklanakarin Journal of Science and Technology (SJST), Vol 36, Iss 5, Pp 547-553 (2014)
Phyllanthus amarus Schum. & Thonn. has been used for the treatment of various diseases. Previous in vitro study in human liver microsome demonstrated the inhibitory activity of P. amarus extract on CYP3A4, an enzyme responsible for various drug met
Externí odkaz:
https://doaj.org/article/d6f51056462e43f3a0029c45efcfc04a
Autor:
Werawath Mahatthanatrakul, Tharinee Nontaput, Somchai Sriwiriyajan, Wibool Ridtitid, Malinee Wongnawa
Publikováno v:
Songklanakarin Journal of Science and Technology (SJST), Vol 30, Iss 3, Pp 307-312 (2008)
The objective of this study was to compare the rate and extent of absorption of a generic risperidone (Iperdal®) with a reference formulation (Risperdal®) when given orally. The study was an open label, randomized, two-period, two-sequence,single d
Externí odkaz:
https://doaj.org/article/0d7cb4793a57457294ba7b7186337af4
Autor:
W. Pipatrattanaseree, Somchai Sriwiriyajan, N. Rujimamahasan, W. Ridtitid, Malinee Wongnawa, Werawath Mahatthanatrakul, Jutima Boonleang
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 37:221-225
Summary What is known and objective: Risperidone is an atypical antipsychotic agent used for the treatment of schizophrenia. It is mainly metabolized by human cytochrome P450 CYP2D6 and partly by CYP3A4 to 9-hydroxyrisperidone. Ketoconazole is used a
Publikováno v:
Clinical Therapeutics. 32:1842-1853
Background: Data regarding the pharmacokinetic properties of risperidone in the Thai population are limited. A new generic tablet formulation was recently developed, but bioequivalence research is necessary to obtain marketing authorization for it in
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 32:585-593
Summary Background: Praziquantel, a broad-spectrum anthelminthic, has been reported to undergo extensive first-pass metabolism by cytochrome P450 (CYP) enzymes in vivo. Ketoconazole, a potent CYP3A4 inhibitor, is known to markedly increase plasma con
Publikováno v:
European Journal of Clinical Pharmacology. 63:479-483
To investigate the effect of efavirenz on the ketoconazole pharmacokinetics in HIV-infected patients.Twelve HIV-infected patients were assigned into a one-sequence, two-period pharmacokinetic interaction study. In phase one, the patients received 400
Autor:
Werawath Mahatthanatrakul, Malinee Wongnawa, Wibool Ridtitid, Maseetoh Samaeng, Somchai Sriwiriyajan
Publikováno v:
Biopharmaceuticsdrug disposition. 32(3)
Objective. To investigate the pharmacokinetic interaction between ciprofloxacin and itraconazole in healthy male volunteers. Methods. Ten healthy male volunteers were assigned into a 2-sequence, 3-period pharmacokinetic interaction study. In phase 1,
Publikováno v:
Arzneimittel-Forschung. 60(6)
The objective of this study was to develop a rapid and simplified, reliable high-performance liquid chromatography (HPLC) method for quantification of cefpirome (CAS 98753-19-6) in plasma. After precipitation of the plasma containing the internal sta
Autor:
Wibool Ridtitid, K Rattana, Werawath Mahatthanatrakul, Somchai Sriwiriyajan, Malinee Wongnawa
Publikováno v:
International journal of clinical pharmacology and therapeutics. 46(9)
Aim: To study the bioequivalence of a generic quetiapine (Quantia 200®, manufactured by the Unison Laboratories Co., Ltd., Bangkok, Thailand) and the innovator product (Seroquel®, AstraZeneca, Mac-clesfield, UK). Volunteers and methods: The study w
Publikováno v:
Journal of clinical pharmacy and therapeutics. 32(2)
Summary Background: Although cytochrome P450 (CYP) 2D6 is often thought to be the only CYP responsible for the metabolism of risperidone, many reports suggest that CYP3A may be involved too. Rifampin, a potent CYP3A inducer, has been known to markedl