A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease

Autor: Van Leuven Fred, Wera Stefaan, Van der Auwera Ingrid, Henderson Samuel T

Publikováno v: Nutrition & Metabolism, Vol 2, Iss 1, p 28 (2005)

Abstract Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder that primarily strikes the elderly. Studies in both humans and animal models have linked the consumption of cholesterol and saturated fats with amyloid-β (Aβ)

Externí odkaz: https://doaj.org/article/39ac0d7e67a542a28f06c6c0998fb35c

Therapeutic Effects of PKC Activators in Alzheimer's Disease Transgenic Mice

Autor: Etcheberrigaray, René, Tan, Mathew, Dewachter, Ilse, Kuipéri, Cuno, Van der Auwera, Ingrid, Wera, Stefaan, Qiao, Lixin, Bank, Barry, Nelson, Thomas J., Kozikowski, Alan P., Van Leuven, Fred, Alkon, Daniel L., Witkop, Bernhard

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2004 Jul . 101(30), 11141-11146.

Externí odkaz: https://www.jstor.org/stable/3372866

Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease

Autor: Dumbacher, Michael, Van Dooren, Tom, Princen, Katrien, De Witte, Koen, Farinelli, Mélissa, Lievens, Sam, Tavernier, Jan, Dehaen, Wim, Wera, Stefaan, Winderickx, Joris, Allasia, Sara, Kilonda, Amuri, Spieser, Stéphane, Marchand, Arnaud, Chaltin, Patrick, Hoogenraad, Casper C, Griffioen, Gerard, Celbiologie, Sub Cell Biology

Publikováno v: Molecular Neurodegeneration, 13(1). BioMed Central
Molecular Neurodegeneration
MOLECULAR NEURODEGENERATION
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-21 (2018)

Background Neuronal Ca2+ dyshomeostasis and hyperactivity play a central role in Alzheimer’s disease pathology and progression. Amyloid-beta together with non-genetic risk-factors of Alzheimer’s disease contributes to increased Ca2+ influx and ab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4d35630ea8fbf8b0de4925d3a4e58c
https://dspace.library.uu.nl/handle/1874/376128

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Inhibition of translation by mRNA encoding NTPP-1, a nuclear inhibitor of protein phosphatase-1.

Autor: Wera, Stefaan¹, Van Eynde, Aleyde¹, Stalmans, Willy¹, Bollen, Mathieu¹ mathieu.bollen@med.kuleuven.ac.be

Publikováno v: European Journal of Biochemistry. 7/1/97, Vol. 247 Issue 1, p411-415. 5p.