Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Weon Sup, Shin"'
Autor:
Peter Verwilst, Weon Sup Shin, Joung Hae Lee, Seyoung Koo, Soon Ki Park, Jong Seung Kim, Sung Gil Chi
Publikováno v:
Chemical Communications. 53:1281-1284
We report on a mitochondria-specific combinational theranostic agent, 1. This system contains a chlorambucil prodrug and an aggregation induced emission dye. In addition, compound 1 bears both an intracellular thiol-triggered moiety and a mitochondri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c396f32dc9a524e6e1169dd2f98e1d3
https://doi.org/10.1039/c6cc08977a
https://doi.org/10.1039/c6cc08977a
Autor:
Jong Seung Kim, Weon Sup Shin, Rajesh Kumar, Kwan Soo Hong, Hyunseung Lee, Jiyou Han, Eun Joong Kim, Hyunmin Kim, Sankarprasad Bhuniya
Publikováno v:
Biomaterials. 104:119-128
Hypoxia, a distinguished feature of various solid tumors, has been considered as a key marker for tumor progression. Inadequate vasculature and high interstitial pressures result in relatively poor drug delivery to these tumors. Herein, we developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b70fb1fde2eaf4d78e5f0b85432dea3
https://doi.org/10.1016/j.biomaterials.2016.07.010
https://doi.org/10.1016/j.biomaterials.2016.07.010
Autor:
Doan Thanh Nhan, Nguyen Thi Ai Nhung, Duong Tuan Quang, Weon Sup Shin, Nguyen Khoa Hien, Nguyen Tien Trung, Hoang Van Duc, Dang Ung Van, Jong Seung Kim
Publikováno v:
Dyes and Pigments. 131:301-306
Herein, we report the design and preparation of a benzothiazolium hemicyanine derivative that exhibits red emission at 585 nm. Its complex with Hg 2+ may be used for selective and sensitive sensing of thiol biomolecules through the reversible visual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d5a8f08bd3afb887ccd7f71bb78cd6a
https://doi.org/10.1016/j.dyepig.2016.03.050
https://doi.org/10.1016/j.dyepig.2016.03.050
Publikováno v:
Bioconjugate Chemistry. 27:1419-1426
The development of targeted and effective theranostic (therapeutic and diagnostic) chemotherapeutic agents is highly desirable for precise diagnosis and treatment of cancer. To realize this goal, we developed a cancer-targeting and enzyme-triggered t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15beaf7266b9ea1df143b62111463eec
https://doi.org/10.1021/acs.bioconjchem.6b00184
https://doi.org/10.1021/acs.bioconjchem.6b00184
Autor:
Hyunmin Kim, Hyunseung Lee, Jong Seung Kim, Weon Sup Shin, Kwan Soo Hong, Eun Joong Kim, Sankarprasad Bhuniya
Publikováno v:
ACS Applied Materials & Interfaces. 8:10266-10273
A novel dual imaging probe for in vivo magnetic resonance imaging (MRI) and optical imaging was developed by combining gadolinium (Gd)-chelating MR probe and a near-infrared (NIR) fluorophore, aza-BODIPY (AB; BODIPY = boron-dipyrromethene). This aza-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1841a94106439bdd099cff42920c9920
https://doi.org/10.1021/acsami.6b03344
https://doi.org/10.1021/acsami.6b03344
Publikováno v:
Chemical Communications. 52:12685-12693
Host-guest recognition plays an important role in biological analysis and biosensing. Accordingly, great efforts have been devoted to the development of sensors using versatile 3D surface materials. These functionalized nanomaterials possess the adva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb5d4c46d95bbe08235fd250335c023
https://doi.org/10.1039/c6cc05876k
https://doi.org/10.1039/c6cc05876k
Publikováno v:
ChemInform. 47
Host–guest recognition plays an important role in biological analysis and biosensing. Accordingly, great efforts have been devoted to the development of sensors using versatile 3D surface materials. These functionalized nanomaterials possess the ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d9898e99bbb88a9e2c7bc27715c7849
https://doi.org/10.1002/chin.201650251
https://doi.org/10.1002/chin.201650251
Autor:
Weon Sup, Shin, Min-Goo, Lee, Peter, Verwilst, Joung Hae, Lee, Sung-Gil, Chi, Jong Seung, Kim
Publikováno v:
Chemical Science
A mitochondria targeted AIE fluorophore was further decorated with an NQO1 cleavable masking unit and showed selective targeting to and activation in cancer cells resulting in bright AIE fluorescence and apoptosis triggered by mitochondrial dysfuncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5da5f776a747e1609a63b78f720909ce
https://pubmed.ncbi.nlm.nih.gov/30034745
https://pubmed.ncbi.nlm.nih.gov/30034745
Publikováno v:
CHEMICAL SCIENCE(7): 9
Tissue selective targeting and specific suborganellular localization combined with an efficient pathology associated enzymatic activation of drugs in drug delivery systems may exhibit a clear advantage over conventional cancer treatment. Here, a mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6dfd3a21c26341e447612cad60e62f1
https://lirias.kuleuven.be/handle/123456789/657315
https://lirias.kuleuven.be/handle/123456789/657315
Autor:
Seyoung Koo, Kyoung Sunwoo, Rajesh Kumar, Weon Sup Shin, Jong Seung Kim, Won Young Kim, Sankarprasad Bhuniya
Publikováno v:
Chemical Society reviews. 44(19)
The advances in genomics, proteomics, and bioinformatics have directed the development of new anticancer agents to reduce drug abuse and increase safe and specific drug treatment. Theranostics, combining therapy and diagnosis, is an appealing approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a6e1814be3a3c6b97fa141dd669742
https://pubmed.ncbi.nlm.nih.gov/26118960
https://pubmed.ncbi.nlm.nih.gov/26118960