Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Wenzhen Yin"'
Autor:
Chen Li, Ni An, Qingru Song, Yuelei Hu, Wenzhen Yin, Qi Wang, Yinpeng Le, Wenting Pan, Xinlong Yan, Yunfang Wang, Juan Liu
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-25 (2024)
Abstract Over the past decade, organoids have emerged as a prevalent and promising research tool, mirroring the physiological architecture of the human body. However, as the field advances, the traditional use of animal or tumor-derived extracellular
Externí odkaz:
https://doaj.org/article/65ee238d0c744ecb89f4ee5853d0c163
Autor:
Juan Liu, Ariel Hanson, Wenzhen Yin, Qiao Wu, Eliane Wauthier, Jinmei Diao, Timothy Dinh, Jeff Macdonald, Ruihong Li, Masahiko Terajima, Mitsuo Yamauchi, Ziye Chen, Praveen Sethupathy, Jiahong Dong, Lola M. Reid, Yunfang Wang
Publikováno v:
Bioactive Materials, Vol 43, Iss , Pp 162-180 (2025)
The creation of ex vivo human liver models has long been a critical objective in academic, clinical, and pharmaceutical research, particularly for drug development, where accurate evaluation of hepatic metabolic dynamics is crucial. We have developed
Externí odkaz:
https://doaj.org/article/99bd25e7d23342b3bdb50e7cb5adf686
Autor:
Yuan Liang, Chao Luo, Lijun Sun, Tiange Feng, Wenzhen Yin, Yunhua Zhang, Michael W. Mulholland, Weizhen Zhang, Yue Yin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Whether intestinal Leucine-rich repeat containing G-protein-coupled receptor 4 (LGR4) impacts nutrition absorption and energy homeostasis remains unknown. Here, we report that deficiency of Lgr4 (Lgr4 iKO ) in intestinal epithelium decreased
Externí odkaz:
https://doaj.org/article/d0530d03ea864df787baf980d668a0d4
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
The liver, as the body’s primary organ for maintaining internal balance, is composed of numerous hexagonal liver lobules, each sharing a uniform architectural framework. These liver lobules serve as the basic structural and functional units of the
Externí odkaz:
https://doaj.org/article/bc33c92fc9c74a6e98ff078af2e3ed4c
Autor:
Yuan Liang, Wenzhen Yin, Chao Luo, Lijun Sun, Tiange Feng, Yunhua Zhang, Yue Yin, Weizhen Zhang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Long-term intermediate fasting before pregnancy in mice disrupts intestinal homeostasis of offspring with subsequent glucose and lipid metabolism disorder, mediated by a reduction in beneficial microbiota such as Lactobacillus intestinalis.
Externí odkaz:
https://doaj.org/article/20bad1d0be58410d961fb8330d349c14
Autor:
Qi Wang, Juan Liu, Wenzhen Yin, Dawei Sun, Zhongsong Man, Shangwei Jiang, Xiufeng Ran, Yuxin Su, Yunfang Wang, Jiahong Dong
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Hepatocellular carcinoma (HCC) is a highly malignant tumor with a poor prognosis. More than 30% of patients with diagnosed HCC have abnormally high expression of fibroblast growth factor receptor 4 (FGFR4). Currently, clinical trials for a variety of
Externí odkaz:
https://doaj.org/article/a5d1e2c4f8604b46a3510e1a67f8a7d2
Autor:
Bahetiyaer Huwatibieke, Wenzhen Yin, Lingchao Liu, Yuxin Jin, Xinxin Xiang, Jingyan Han, Weizhen Zhang, Yin Li
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The mammalian target of rapamycin (mTOR) is an important protein kinase that senses changes in extracellular and intracellular energy levels and plays a key role in regulating energy metabolism. Brown adipose tissue, which can be converted to white a
Externí odkaz:
https://doaj.org/article/760199d4234a4f6987383aaebeb6bfbe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Pancreatic cancer risk increases in obese and diabetic people. In this manuscript, the authors show that Roux-en-Y gastric bypass surgery (RYGB) decreases the impact of pancreatic cancer in a mouse model; this effect seems independent of weight loss
Externí odkaz:
https://doaj.org/article/70899d1993ef44389b264b81f3f11a5f
Autor:
Yuan Liang, Chao Luo, Lijun Sun, Tiange Feng, Wenzhen Yin, Yunhua Zhang, Mulholland, Michael W., Weizhen Zhang, Yue Yin
Publikováno v:
Nature Communications; 5/23/2024, Vol. 15 Issue 1, p1-12, 12p, 6 Graphs
Autor:
Wenzhen Yin, Lijun Sun, Yuan Liang, Chao Luo, Tiange Feng, Yunhua Zhang, Weizhen Zhang, Yue Yin
Publikováno v:
The FASEB Journal. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53d80e31b76a7dd0cbcc2d59a267d4d7
https://doi.org/10.1096/fj.202201907r
https://doi.org/10.1096/fj.202201907r