Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Wenzhe Du"'
Publikováno v:
Cancer Imaging, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Colorectal cancer (CRC) can develop through various pathogenetic pathways, and one of the primary pathways is high microsatellite instability (MSI-H)/deficient mismatch repair (dMMR). This study investigated the correlation betwee
Externí odkaz:
https://doaj.org/article/9754bd1f75954b6091ec89e9ce3b7b99
Publikováno v:
Engineered Regeneration, Vol 4, Iss 3, Pp 289-303 (2023)
Patients with brain injury can suffer disability and accompanying complications. Current clinical treatments have significant limitations to successful repair due to the complexity of the pathological processes and the inhibitory microenvironment tha
Externí odkaz:
https://doaj.org/article/56a3b0e03dc34f11a82b486b0d2955b2
Autor:
Shengkai Xia, Wenzhe Duan, Mingxin Xu, Mengqi Li, Mengyi Tang, Song Wei, Manqing Lin, Encheng Li, Wenwen Liu, Qi Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Brain metastasis (BM) is common among cases of advanced non-small cell lung cancer (NSCLC) and is the leading cause of death for these patients. Mesothelin (MSLN), a tumor-associated antigen expressed in many solid tumors, has bee
Externí odkaz:
https://doaj.org/article/2576dde8f1c74c4f8d9f75d1687fb139
Autor:
Mengyi Tang, Mingxin Xu, Jian Wang, Ye Liu, Kun Liang, Yinuo Jin, Wenzhe Duan, Shengkai Xia, Guohui Li, Huiying Chu, Wenwen Liu, Qi Wang
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Patients who have non‐small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations are more prone to brain metastasis (BM) and poor prognosis. Previous studies showed that the tumor microenvironment of BM in these
Externí odkaz:
https://doaj.org/article/88e115f98f474a4ba26812cdc045acdc
Autor:
Wenzhe Duan, Wenwen Liu, Shengkai Xia, Yang Zhou, Mengyi Tang, Mingxin Xu, Manqing Lin, Xinyu Li, Qi Wang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Resistance to pemetrexed (PEM), a rare chemotherapeutic agent that can efficiently cross the blood-brain barrier, limits the therapeutic efficacy for patients with lung cancer brain metastasis (BM). Aldo-keto reductase family 1 B1
Externí odkaz:
https://doaj.org/article/39a4bf8e81eb49fcbbd17cb0727bdc71
Autor:
Lixuan Yang, Yutian Ao, Yannan Li, Baoan Dai, Jingchun Li, Wenzhe Duan, Wei Gao, Zhonghui Zhao, Zhenyun Han, Rongjuan Guo
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-18 (2023)
Abstract Objective Patients with hypertension have a risk of depression. Morinda officinalis oligosaccharides (MOOs) have anti-depressant properties. In this study, we aimed to determine whether MOOs can improve the symptoms of depression in individu
Externí odkaz:
https://doaj.org/article/db8e0ed903f14098a1b60a309d6918f2
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 10, Pp n/a-n/a (2023)
Abstract Background Aggressive brain tumours, whether primary gliomas or secondary metastases, are characterised by hypervascularisation and are fatal. Recent research has emphasised the crucial involvement of endothelial cells (ECs) in all brain tum
Externí odkaz:
https://doaj.org/article/8254872674ed4cfb9d04770efe9dd666
Publikováno v:
ACS Catalysis. 1:1022-1034
This paper describes the protease-catalyzed synthesis of oligo(l-Lys) from l-Lys ethyl ester (l-Lys-Et) in an aqueous reaction medium at controlled pH using a pH-stat. Four proteases (papain, bromelain, α-chymotrypsin, and trypsin) were studied to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17e87c79b990a72e896c40a1fa872952
https://doi.org/10.1021/cs2002884
https://doi.org/10.1021/cs2002884
Publikováno v:
Chemical communications (Cambridge, England). 49(4)
A unique route to perfectly alternating oligopeptides is described. First, AG-OEt was prepared by standard chemical coupling. Then, AG-OEt was converted by papain-catalysis in 30 s to (AG)(x) (80%-yield, x = 9.4 ± 0.3). Extension of this strategy to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1f755d3390567d560c6e93f7b84632
https://pubmed.ncbi.nlm.nih.gov/23190865
https://pubmed.ncbi.nlm.nih.gov/23190865
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Glucose-regulating protein 78 (GRP78) is a molecular chaperone in the endoplasmic reticulum (ER) that promotes folding and assembly of proteins, controls the quality of proteins, and regulates ER stress signaling through Ca2+ binding to the
Externí odkaz:
https://doaj.org/article/319ae496bafe49b2b2a08c22b272f444