Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Wenyu Wen"'
Autor:
Xinyue Lv, Peipei Ding, Luying Li, Ling Li, Danlei Zhou, Xiaochao Wang, Jianfeng Chen, Wei Zhang, Qi Wang, Tian Liao, Wenyu Wen, Dawang Zhou, Qing-Hai Ji, Xianghuo He, Qun-Ying Lei, Weiguo Hu
Publikováno v:
Molecular Metabolism, Vol 75, Iss , Pp 101766- (2023)
Sufficient evidence has linked many different types of cancers and T2D through shared risk factors; however, the underlying mechanisms are not fully understood. α-Hydroxybutyrate (α-HB), a byproduct metabolite increased in diabetes and cancer, incl
Externí odkaz:
https://doaj.org/article/cacb6d4737814e1abb411fe1c2ef9871
Autor:
Jiawen Xu, Xin Deng, Aihong Gu, Yuqun Cai, Yunyun Huang, Wen Zhang, Yiqing Zhang, Wenyu Wen, Yunli Xie
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112677- (2023)
Summary: Polarity proteins regulate the proliferation and differentiation of neural progenitors to generate neurons during brain development through multiple signaling pathways. However, how cell polarity couples the signaling pathways remains unclea
Externí odkaz:
https://doaj.org/article/300bcaaa8708465a8aa88b0ece864d90
Autor:
Wei Zhang, Xin Zhang, Sheng Huang, Jianfeng Chen, Peipei Ding, Qi Wang, Luying Li, Xinyue Lv, Ling Li, Pingzhao Zhang, Danlei Zhou, Wenyu Wen, Yiping Wang, Qun‐Ying Lei, Jiong Wu, Weiguo Hu
Publikováno v:
Molecular Oncology, Vol 15, Iss 5, Pp 1466-1485 (2021)
Tumor growth, especially in the late stage, requires adequate nutrients and rich vasculature, in which PKM2 plays a convergent role. It has been reported that PKM2, together with FOXM1D, is upregulated in late‐stage colorectal cancer and associated
Externí odkaz:
https://doaj.org/article/92870627dcd54d3d9dae022c4ff54fd6
Autor:
Feng-Min Liu, Yu-fei Gao, Yanyan Kong, Yihui Guan, Jinsen Zhang, Shuai-Hong Li, Dan Ye, Wenyu Wen, Chuantao Zuo, Wei Hua
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Non-invasive diagnosis of IDH1 mutation for gliomas has great clinical significance, and PET has natural advantage to detect metabolism, as IDH mutated gliomas share lower glucose consumption. Methods Clinical data of patients wit
Externí odkaz:
https://doaj.org/article/729bec0131124d6285692998711433fe
Autor:
Ziheng Liu, Ying Yang, Aihong Gu, Jiawen Xu, Ying Mao, Haojie Lu, Weiguo Hu, Qun-Ying Lei, Zhouhua Li, Mingjie Zhang, Yu Cai, Wenyu Wen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
The evolutionarily conserved complex, the Par proteins, regulates cell polarity. Here, the authors show that in Drosophila neuroblasts, the Par complex exhibits liquid–liquid phase separation dependent on the cell cycle.
Externí odkaz:
https://doaj.org/article/23dbf619503b41d390a1459f50303a9b
Autor:
Zhen Wang, Ziheng Liu, Xing Chen, Jingyu Li, Weiyi Yao, Shijing Huang, Aihong Gu, Qun-Ying Lei, Ying Mao, Wenyu Wen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
HECT type E3 ligases are key regulators of cell growth and proliferation. Here the authors present the crystal structures of the Nedd4 family E3 ligase WWP1 in a closed and semi-open state and in combination with mutagenesis experiments identify a mu
Externí odkaz:
https://doaj.org/article/ed0c3c09d75e424cad3894422e8ab3e0
Autor:
Zelin Shan, Yuting Tu, Ying Yang, Ziheng Liu, Menglong Zeng, Huisha Xu, Jiafu Long, Mingjie Zhang, Yu Cai, Wenyu Wen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Polarized localization of Numb and Pon in Drosophila neuroblasts (NBs) enables their unequal segregation during asymmetric cell divisions. Here, the authors demonstrate liquid-liquid phase separation of Pon and Numb in NBs mediated by multivalent int
Externí odkaz:
https://doaj.org/article/f45e83778d8742c9b81a80ceb914abed
Autor:
Glazenburg, Marieke Margaretha, Hettema, Nynke Marije, Laan, Liedewij, Remy, Ophélie, Laloux, Géraldine, Brunet, Thibaut, Xin Chen, Yee Han Tee, Wenyu Wen, Rizvi, Mohd Suhail, Jolly, Mohit Kumar, Riddell, Meghan
Publikováno v:
Journal of Cell Science; Mar2024, Vol. 137 Issue 5, p1-7, 7p
Autor:
Dongdong Li, Shijing Huang, Yongping Chai, Ruiqian Zhao, Jing Gong, Qiangfeng Cliff Zhang, Guangshuo Ou, Wenyu Wen
Publikováno v:
Science China Life Sciences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::814c87039d763637c11d0bb75c53e64f
https://doi.org/10.1007/s11427-022-2332-5
https://doi.org/10.1007/s11427-022-2332-5
Autor:
Hongdan Zheng, Wenyu Wen
Publikováno v:
Acta Biochimica et Biophysica Sinica.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa7c692f8cac5c081d7b487ea19f32b0
https://doi.org/10.3724/abbs.2023093
https://doi.org/10.3724/abbs.2023093