Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Wenyang JIANG"'
Publikováno v:
Chinese Journal of Lung Cancer, Vol 27, Iss 4, Pp 283-290 (2024)
Non-small cell lung cancer (NSCLC) is a prevalent tumour type in our country, with lung squamous carcinoma being a commonly observed NSCLC subtype besides lung adenocarcinoma. Epidermal growth factor receptor (EGFR) is a significant driver gene in lu
Externí odkaz:
https://doaj.org/article/b9c23f5643194643905fa14057dbbb17
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background Epithelial mesenchymal transformation (EMT) in alveolar type 2 epithelial cells (AT2) is closely associated with pulmonary fibrosis (PF). Histone deacetylase 3 (HDAC3) is an important enzyme that regulates protein stability by mod
Externí odkaz:
https://doaj.org/article/001c9d3bde8d40b9a130dbfc66fcb1e7
Autor:
Yu Ning, Peisen Huang, Guihao Chen, Yuyan Xiong, Zhaoting Gong, Chunxiao Wu, Junyan Xu, Wenyang Jiang, Xiaosong Li, Ruijie Tang, Lili Zhang, Mengjin Hu, Jing Xu, Jun Xu, Haiyan Qian, Chen Jin, Yuejin Yang
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Extracellular vesicles (EVs) derived from bone marrow mesenchymal stem cells (MSCs) pretreated with atorvastatin (ATV) (MSCATV-EV) have a superior cardiac repair effect on acute myocardial infarction (AMI). The mechanisms, however
Externí odkaz:
https://doaj.org/article/5755746d583b4ea89effe21a27915135
Publikováno v:
Chinese Journal of Lung Cancer, Vol 26, Iss 1, Pp 59-65 (2023)
Chimeric antigen receptor T cell (CAR-T) therapy has shown remarkable success in treating hematological malignancies. However, CAR-T therapy for solid tumors is still limited due to the unique solid-tumor microenvironment and heterogeneous target ant
Externí odkaz:
https://doaj.org/article/fe538c8102a44dd5b378b17d76b42b2a
Autor:
Yuyan Xiong, Ruijie Tang, Junyan Xu, Wenyang Jiang, Zhaoting Gong, Lili Zhang, Yu Ning, Peisen Huang, Jun Xu, Guihao Chen, Xiaosong Li, Mengjin Hu, Jing Xu, Chunxiao Wu, Chen Jin, Xiangdong Li, Haiyan Qian, Yuejin Yang
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract Background Bone marrow cells (BMCs), especially mesenchymal stem cells (MSCs), have shown attractive application prospects in acute myocardial infarction (AMI). However, the weak efficacy becomes their main limitation in clinical translation
Externí odkaz:
https://doaj.org/article/b1278d858a714a99ad634b63b3db0551
Autor:
Ruyuan He, Bohao Liu, Rui Xiong, Boxin Geng, Heng Meng, Weichen Lin, Bo Hao, Lin Zhang, Wei Wang, Wenyang Jiang, Ning Li, Qing Geng
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Itaconate, a metabolite produced during inflammatory macrophage activation, has been extensively described to be involved in immunoregulation, oxidative stress, and lipid peroxidation. As a form of iron and lipid hydroperoxide-dependent regu
Externí odkaz:
https://doaj.org/article/2f0a49725c994bff8826064c8c59cfa5
Autor:
Yuyan Xiong, Ruijie Tang, Junyan Xu, Wenyang Jiang, Zhaoting Gong, Lili Zhang, Xiaosong Li, Yu Ning, Peisen Huang, Jun Xu, Guihao Chen, Chen Jin, Xiangdong Li, Haiyan Qian, Yuejin Yang
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-14 (2022)
Abstract Background Bone marrow-derived mesenchymal stem cells (MSCs), which possess immunomodulatory characteristic, are promising candidates for the treatment of acute myocardial infarction (AMI). However, the low retention and survival rate of MSC
Externí odkaz:
https://doaj.org/article/e20c973d3a854e92910dd806e4aa1876
Autor:
Yanyun Du, Qianwen Peng, Du Cheng, Ting Pan, Wanwei Sun, Heping Wang, Xiaojian Ma, Ruirui He, Huazhi Zhang, Zhihui Cui, Xiong Feng, Zhiqiang Liu, Tianxin Zhao, Wenjun Hu, Lei Shen, Wenyang Jiang, Na Gao, Bradley N. Martin, Cun-Jin Zhang, Zhanguo Zhang, Chenhui Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Cancer cells producing ligands for the immune checkpoint molecules PD-1 and CTLA-4 is an important mechanism of tumour immune resistance. Here authors show that BTNL2 expression on cancer cells generates a dysfunctional tumour immune microenvironment
Externí odkaz:
https://doaj.org/article/bc2c48f5c4eb46b6b81e3b0918f911d1
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background Heart failure, which is characterized by cardiac remodelling, is one of the most common chronic diseases in the aged. Stimulator of interferon genes (STING) acts as an indispensable molecule modulating immune response and inflamma
Externí odkaz:
https://doaj.org/article/0540ee358583444eb7a494c04aac8a33
Publikováno v:
Cancer Medicine, Vol 9, Iss 6, Pp 1999-2009 (2020)
Abstract Long intergenic nonprotein coding RNA p53‐induced transcript (LINC‐PINT) has been reported to participate in various cancers. Here, we investigated the effects of LINC‐PINT on lung cancer progression. Firstly, in our study, we implied
Externí odkaz:
https://doaj.org/article/c20091f1144a4a9f84478cab1bc53a4b