Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Wenyan Ren"'
Intranasal boosting with RBD-HR protein vaccine elicits robust mucosal and systemic immune responses
Autor:
Li Chen, Wenyan Ren, Hong Lei, Jiayu Wang, Haiying Que, Dandan Wan, Aqu Alu, Dandan Peng, Minyang Fu, Weiqi Hong, Yuhe Huang, Xiangrong Song, Guangwen Lu, Xiawei Wei
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 101066- (2024)
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has decreased the efficacy of SARS-CoV-2 vaccines in containing coronavirus disease 2019 (COVID-19) over time, and booster vaccination strategies are urgently nece
Externí odkaz:
https://doaj.org/article/de498c355822410c9c314b98a69a739d
Autor:
Hong Lei, Aqu Alu, Jingyun Yang, Xi He, Cai He, Wenyan Ren, Zimin Chen, Weiqi Hong, Li Chen, Xuemei He, Li Yang, Jiong Li, Zhenling Wang, Wei Wang, Yuquan Wei, Shuaiyao Lu, Guangwen Lu, Xiangrong Song, Xiawei Wei
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Mucosal immunity plays a significant role in the first-line defense against viruses transmitted and infected through the respiratory system, such as SARS-CoV-2. However, the lack of effective and safe adjuvants currently limits the developme
Externí odkaz:
https://doaj.org/article/4c7a1a957b664368a7ddf9665976879b
Autor:
Baoshi Yuan, Kexin Shi, Juanmin Zha, Yujia Cai, Yue Gu, Kai Huang, Wenchang Yue, Qiaocheng Zhai, Ning Ding, Wenyan Ren, Weiqi He, Ying Xu, Tao Wang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Osteosarcoma is the most common primary malignant bone tumour in children and adolescents. Chemoresistance leads to poor responses to conventional therapy in patients with osteosarcoma. The discovery of novel effective therapeutic targets an
Externí odkaz:
https://doaj.org/article/74860d71f41b4dd685ee0cce8882e5dc
Autor:
Haiying Que, Weiqi Hong, Tianxia Lan, Hao Zeng, Li Chen, Dandan Wan, Zhenfei Bi, Wenyan Ren, Min Luo, Jingyun Yang, Cai He, Ailing Zhong, Xiawei Wei
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract For coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), 15–30% of patients are likely to develop COVID-19-related acute respiratory distress syndrome (ARDS). There are still few effe
Externí odkaz:
https://doaj.org/article/0b63e69aba434510838814d61e30b2d8
Autor:
Cai He, Jingyun Yang, Weiqi Hong, Zimin Chen, Dandan Peng, Hong Lei, Aqu Alu, Xuemei He, Zhenfei Bi, Xiaohua Jiang, Guowen Jia, Yun Yang, Yanan Zhou, Wenhai Yu, Cong Tang, Qing Huang, Mengli Yang, Bai Li, Jingmei Li, Junbin Wang, Haiying Que, Li Chen, Wenyan Ren, Dandan Wan, Jiong Li, Wei Wang, Guobo Shen, Zhiwei Zhao, Li Yang, Jinliang Yang, Zhenling Wang, Zhaoming Su, Yuquan Wei, Xiaobo Cen, Yoshimasa Tanaka, Xiangrong Song, Shuaiyao Lu, Xiaozhong Peng, Guangwen Lu, Xiawei Wei
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The SARS-CoV-2 Omicron variant has quickly become the predominant circulating variant, due to the high transmissibility and immune escape. Here, the authors develop a trimeric protein vaccine candidate and show a sustained humoral immune response, an
Externí odkaz:
https://doaj.org/article/6931d87e1b9f415882b4ac5ac20fee24
Autor:
Dandan Peng, Tingmei Zhao, Weiqi Hong, Minyang Fu, Cai He, Li Chen, Wenyan Ren, Hong Lei, Jingyun Yang, Aqu Alu, Yanghong Ni, Jian Liu, Jiong Li, Wei Wang, Guobo Shen, Zhiwei Zhao, Li Yang, Jinliang Yang, Zhenling Wang, Yoshimasa Tanaka, Guangwen Lu, Xiangrong Song, Xiawei Wei
Publikováno v:
MedComm, Vol 4, Iss 2, Pp n/a-n/a (2023)
Abstract BA.4 and BA.5 (BA.4/5), the subvariants of Omicron, are more transmissible than BA.1 with more robust immune evasion capability because of its unique spike protein mutations. In light of such situation, the vaccination against severe acute r
Externí odkaz:
https://doaj.org/article/c5d5e2397951419799d42876e6ce0022
Autor:
Yu Liu, Zhe Zhang, Min Luo, Hao Zeng, Yuquan Wei, Siyuan Chen, Xiaohe Tian, Tianqi Lu, Ziqi Zhang, Zhenfei Bi, Tianxia Lan, Fei Mo, Jingyun Yang, Xuemei He, Weiqi Hong, Ruyu Pi, Wenyan Ren, Xiawei Wei
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Background Mitochondrial transcription factor A (TFAM) is a transcription factor that maintains mitochondrial DNA (mtDNA) stabilization and initiates mtDNA replication. However, little is known about the immune regulation function and TFAM expression
Externí odkaz:
https://doaj.org/article/26abb994be4d4725a769046a4d5da383
Autor:
Hong Lei, Aqu Alu, Jingyun Yang, Wenyan Ren, Cai He, Tianxia Lan, Xuemei He, Li Yang, Jiong Li, Zhenling Wang, Xiangrong Song, Wei Wang, Guangwen Lu, Xiawei Wei
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract The outbreak of coronavirus disease 2019 (COVID-19) has posed great threats to global health and economy. Several effective vaccines are available now, but additional booster immunization is required to retain or increase the immune response
Externí odkaz:
https://doaj.org/article/f07f3ff7a36545fca226aec56d59da94
Autor:
Wenyan Ren1, Weiqi Hong1, Jingyun Yang1, Jun Zou1, Li Chen1, Yanan Zhou2, Hong Lei1, Aqu Alu1, Haiying Que1, Yanqiu Gong1, Zhenfei Bi1, Cai He1, Minyang Fu1, Dandan Peng1, Yun Yang2, Wenhai Yu2, Cong Tang2, Qing Huang2, Mengli Yang2, Bai Li2
Publikováno v:
Journal of Clinical Investigation. 9/17/2024, Vol. 134 Issue 18, p1-14. 14p.
Autor:
Zhenfei Bi, Weiqi Hong, Haiying Que, Cai He, Wenyan Ren, Jingyun Yang, Tianqi Lu, Li Chen, Shuaiyao Lu, Xiaozhong Peng, Xiawei Wei
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract The development of animal models for COVID-19 is essential for basic research and drug/vaccine screening. Previously reported COVID-19 animal models need to be established under a high biosafety level condition for the utilization of live SA
Externí odkaz:
https://doaj.org/article/6972ecfacb72457b9cae2f508bb948eb