Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Wenya Shao"'
Autor:
Yu Zhang, Yihua Jiang, Yinhan Li, Zhen Yu, Xinpei Lin, Fuli Zheng, Hong Hu, Wenya Shao, Guangxia Yu, Zhenkun Guo, Siying Wu, Huangyuan Li
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 286, Iss , Pp 117193- (2024)
Paraquat (PQ), a commonly used herbicide, is a potent environmental neurotoxin associated with Parkinson’s disease (PD) and major depressive disorder (MDD). While the involvement of various brain cell types in the etiology of each disorder is well
Externí odkaz:
https://doaj.org/article/ab21356516814419bef0b75491c2d2fe
Autor:
Qianqian Su, Lingyan Wu, Chunyan Zheng, Xianqi Ji, Xinpei Lin, Yu Zhang, Fuli Zheng, Zhenkun Guo, Wenya Shao, Hong Hu, Jinfu Zhou, Yu Jiang, Ying Tang, Siying Wu, Michael Aschner, Huangyuan Li, Guangxia Yu
Publikováno v:
Environment International, Vol 190, Iss , Pp 108897- (2024)
The utilization of Cobalt (Co) has surged due to it is critical role in renewable energy technologies and other high-tech applications. Concurrently, the potential health risks associated with Co exposure have raised concerns. Previous studies, inclu
Externí odkaz:
https://doaj.org/article/0bd3673a5f8f4bff913706bfd054e642
Autor:
Xinpei Lin, Wei Wang, Xiangyu Chang, Cheng Chen, Zhenkun Guo, Guangxia Yu, Wenya Shao, Siying Wu, Qunwei Zhang, Fuli Zheng, Huangyuan Li
Publikováno v:
Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background As the demand and application of engineered nanomaterials have increased, their potential toxicity to the central nervous system has drawn increasing attention. Tunneling nanotubes (TNTs) are novel cell–cell communication that p
Externí odkaz:
https://doaj.org/article/43897ee5bd56444b9c05bf2efba7e0d0
Autor:
Yali Weng, Yu Zhang, Yinhan Li, Xinpei Lin, Zhenkun Guo, Hong Hu, Wenya Shao, Guangxia Yu, Fuli Zheng, Ping Cai, Huangyuan Li, Siying Wu
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 273, Iss , Pp 116169- (2024)
Parkinson's disease (PD) is among the most prevalent neurodegenerative diseases, and approximately one third of patients with PD are estimated to have depression. Paraquat (PQ) exposure is an important environmental risk factor for PD. In this study,
Externí odkaz:
https://doaj.org/article/c4b6a3a2d48a4b7c92122975c1c99d67
Autor:
Xu Liu, Qingqing Wu, Jingwen Wu, Jianxi Liu, Fuli Zheng, Guangxia Yu, Hong Hu, Zhenkun Guo, Siying Wu, Huangyuan Li, Wenya Shao
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 263, Iss , Pp 115356- (2023)
Paraquat (PQ) is an environmental poison that causes clinical symptoms similar to those of Parkinson's disease (PD) in vitro and in rodents. It can lead to the activation of microglia and apoptosis of dopaminergic neurons. However, the exact role and
Externí odkaz:
https://doaj.org/article/12a44c7d891140b0b75da6522a60ab1d
Autor:
Junxiang Wang, Yali Weng, Yinhan Li, Yu Zhang, Jinfu Zhou, Jianping Tang, Xinpei Lin, Zhenkun Guo, Fuli Zheng, Guangxia Yu, Wenya Shao, Hong Hu, Ping Cai, Siying Wu, Huangyuan Li
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 255, Iss , Pp 114804- (2023)
Paraquat (PQ) has been widely acknowledged as an environmental risk factor for Parkinson's disease (PD). However, the interaction between splicing factor and long non-coding RNA (lncRNA) in the process of PQ-induced PD has rarely been studied. Based
Externí odkaz:
https://doaj.org/article/64309b3620784205aab41c96293cb66a
Autor:
Qianqian Su, Nengzhou Chen, Jianping Tang, Junxiang Wang, Wei-Chun Chou, Fuli Zheng, Wenya Shao, Guangxia Yu, Ping Cai, Zhenkun Guo, Minghua He, Huangyuan Li, Siying Wu
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 237, Iss , Pp 113503- (2022)
Paraquat (PQ) is a ubiquitously applied herbicide. Long-term PQ exposure with low dose has been reported to induce abnormal expression of long non-coding RNAs (lncRNAs) in brain nerve cells, which could further lead to Parkinson's disease (PD). N6-me
Externí odkaz:
https://doaj.org/article/13d2bb88b05346699b3c0ef11bd89753
Autor:
Zhenkun Guo, Jianping Tang, Junxiang Wang, Fuli Zheng, Chunchun Zhang, Yuan-Liang Wang, Ping Cai, Wenya Shao, Guangxia Yu, Siying Wu, Huangyuan Li
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 209, Iss , Pp 111832- (2021)
Cobalt has been known for its neurotoxicity in numerous studies. However, the molecular mechanism underlying cobalt-induced neurotoxicity remains largely unknown. In this study, two neuroblastoma (SHSY5Y and N2a) cell lines and a phaeochromocytoma (P
Externí odkaz:
https://doaj.org/article/1847f0e6d9a4447cad794a0fa5287e66
Autor:
Yinyin Zhang, Wenya Shao, Jingwen Wu, Shouxiong Huang, Hongyu Yang, Zhousong Luo, Fuli Zheng, Yuan-Liang Wang, Ping Cai, Zhenkun Guo, Siying Wu, Huangyuan Li
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 208, Iss , Pp 111424- (2021)
Emerging evidences having suggested that particular lncRNAs have a potential effect on PD progression through provoking damage and inflammatory responses of microglia/ dopaminergic cells. In addition, paraquat can be accumulated in human body through
Externí odkaz:
https://doaj.org/article/60a2e9ca2fec424abf64bdd0811a4686
Autor:
Fuli Zheng, Zhousong Luo, Xinpei Lin, Wei Wang, Michael Aschner, Ping Cai, Yuan-Liang Wang, Wenya Shao, Guangxia Yu, Zhenkun Guo, Siying Wu, Huangyuan Li
Publikováno v:
Nanotoxicology
Broad applications of cobalt nanoparticles (CoNPs) have raised increased concerns regarding their potential toxicity. However, the underlining mechanisms of their toxicity have yet to be characterized. Here, we demonstrated that CoNPs reduced cell vi