Rechallenge of immune checkpoint inhibitors in advanced non‐small cell lung cancer

Autor: Gen Lin, Zhijie Wang, Qian Chu, Yi Hu, Dingzhi Huang, Jun Wang, Fan Yang, Wenzhao Zhong, Chengzhi Zhou, Bo Zhu, Xinghao Ai, Baoshan Cao, Yabing Cao, Mingqiu Chen, Xiaohui Chen, Tianqing Chu, Jianchun Duan, Yun Fan, Yong Fang, Shuitu Feng, Weineng Feng, Hui Guo, Chengbo Han, Yong He, Shaodong Hong, Jie Hu, Meijuan Huang, Yan Huang, Da Jiang, Kan Jiang, Richeng Jiang, Bo Jin, Shi Jin, Jisheng Li, Min Li, Ziming Li, Chao Li, Jie Lin, Anwen Liu, Si‐Yang Maggie Liu, Liu Yutao, Zhefeng Liu, Zhe Liu, Zhenhua Liu, Zhentian Liu, Zhigang Liu, Yuping Lu, Tangfeng Lv, Zhiyong Ma, Qian Miao, Min Peng, Xingxiang Pu, Xiu Bao Ren, Jianzhen Shan, Jinlu Shan, Peng Shen, Bo Shen, Meiqi Shi, Yong Song, Zhengbo Song, ChunXia Su, Jianguo Sun, Panwen Tian, Jinliang Wang, Feng Wang, Huijuan Wang, Jialei Wang, Qian Wang, Wenxian Wang, Yan Wang, Lin Wu, Fang Wu, Yang Xia, Congying Xie, Conghua Xie, Tao Xin, Jianping Xiong, Haipeng Xu, Song Xu, Yiquan Xu, Bin Xu, Chunwei Xu, Xiaolong Yan, Zhenzhou Yang, Wenxiu Yao, Yao Yu, Ye Feng, Zongyang Yu, Yongfeng Yu, Dongsheng Yue, Haibo Zhang, HongMei Zhang, Li Zhang, Longfeng Zhang, Qiuyu Zhang, Tongmei Zhang, Bicheng Zhang, Jun Zhao, Mingfang Zhao, Xiaobin Zheng, Qiaofeng Zhong, Jin Zhou, Penghui Zhou, Zhengfei Zhu, Juntao Zou, Zihua Zou

Publikováno v: Thoracic Cancer, Vol 15, Iss 5, Pp 419-426 (2024)

Abstract Immune checkpoint inhibitor (ICI) rechallenge in non‐small cell lung cancer (NSCLC) is a promising therapeutic strategy. The situation for ICI rechallenge can be divided into three categories: adverse events (AEs); resistance to ICIs, and

Externí odkaz: https://doaj.org/article/5593cfcf22cf4de189ad661dbe843899

Circ_0047921 acts as the sponge of miR-1287-5p to stimulate lung cancer progression by regulating proliferation, migration, invasion, and glycolysis of lung cancer cells

Autor: Yuehua Xiao, Shequn Gu, Wenxiu Yao, Ling Qin, Jihui Luo

Publikováno v: World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-13 (2022)

Highlights 1. Circ_0047921 was upregulated in lung cancer tissues and cells. 2. Circ_0047921/miR-1287-5p/LARP1 axis played a key role in proliferation, migration, invasion, EMT and glycolysis of lung cancer cells. 3. Circ_0047921 regulated LARP1 by s

Externí odkaz: https://doaj.org/article/6946f524d954421e99ac248d39492256

Paclitaxel liposome for injection (Lipusu) plus cisplatin versus gemcitabine plus cisplatin in the first‐line treatment of locally advanced or metastatic lung squamous cell carcinoma: A multicenter, randomized, open‐label, parallel controlled clinical study

Autor: Jie Zhang, Yueyin Pan, Qin Shi, Guojun Zhang, Liyan Jiang, Xiaorong Dong, Kangsheng Gu, Huijuan Wang, Xiaochun Zhang, Nong Yang, Yuping Li, Jianping Xiong, Tienan Yi, Min Peng, Yong Song, Yun Fan, Jiuwei Cui, Gongyan Chen, Wei Tan, Aimin Zang, Qisen Guo, Guangqiang Zhao, Ziping Wang, Jianxing He, Wenxiu Yao, Xiaohong Wu, Kai Chen, Xiaohua Hu, Chunhong Hu, Lu Yue, Da Jiang, Guangfa Wang, Junfeng Liu, Guohua Yu, Junling Li, Jianling Bai, Wenmin Xie, Weihong Zhao, Lihong Wu, Caicun Zhou

Publikováno v: Cancer Communications, Vol 42, Iss 1, Pp 3-16 (2022)

Abstract Background Lipusu is the first commercialized liposomal formulation of paclitaxel and has demonstrated promising efficacy against locally advanced lung squamous cell carcinoma (LSCC) in a small‐scale study. Here, we conducted a multicenter

Externí odkaz: https://doaj.org/article/6390005c415f4ea5b107038b3eac3a40

C, N, P, K stoichiometric characteristics of the 'leaf-root-litter-soil' system in dryland plantations

Autor: Yage Li, Xiaoxue Dong, Wenxiu Yao, Chun Han, Shan Sun, Changming Zhao

Publikováno v: Ecological Indicators, Vol 143, Iss , Pp 109371- (2022)

Plantation’s nutrient cycling can regulate and affect the material cycling of ecosystems, which is the key to maintain the sustainable development of the plantation ecosystem. However, the current understanding of the nutrient cycling characteristi

Externí odkaz: https://doaj.org/article/ed1077122fa345bebc270a10b7bff3ce

All-trans retinoic acid reduces cancer stem cell-like cell-mediated resistance to gefitinib in NSCLC adenocarcinoma cells

Autor: Wenxiu Yao, Liyang Wang, Huan Huang, Xin Li, Pinjia Wang, Kun Mi, Jia Cheng, Huifen Liu, Cuirong Gu, Lingxiao Huang, Jianming Huang

Publikováno v: BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)

Abstract Background The enrichment of cancer stem cell-like cells (CSCs) has been considered to be responsible for tumor progression after an initial response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) in patien

Externí odkaz: https://doaj.org/article/c99a0da21d4a44789112c4528646864d