Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Wenxiang Hong"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 4, Pp 1508-1524 (2024)
Macrophage senescence, manifested by the special form of durable cell cycle arrest and chronic low-grade inflammation like senescence-associated secretory phenotype, has long been considered harmful. Persistent senescence of macrophages may lead to m
Externí odkaz:
https://doaj.org/article/07c835cf1fa545d0aabfbabda1972a06
Autor:
Jiajia Wang, Jiaying Wang, Wenxiang Hong, Lulu Zhang, Liqian Song, Qi Shi, Yanfei Shao, Guifeng Hao, Chunyan Fang, Yueping Qiu, Lijun Yang, Zhaoxu Yang, Jincheng Wang, Ji Cao, Bo Yang, Qiaojun He, Qinjie Weng
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Optineurin (OPTN) has been implicated in various biological processes, but its function in dendritic cells (DC) maturation is still unclear. Here the authors show, by characterizing Optn-conditional knockout mice, that the loss of OPTN induces Jak2/S
Externí odkaz:
https://doaj.org/article/ed01766df50a46f3ab6099205d41690e
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
CCR7, collaborated with its ligands CCL19 and CCL21, controls extensive migratory events in the immune system. CCR7-bearing dendritic cells can swarm into T-cell zones in lymph nodes, initiating the antigen presentation and T-cell response. Abnormal
Externí odkaz:
https://doaj.org/article/3e7ddcf80f7e469fa2e2d99d75ba4b6d
Autor:
Zhaoxu Yang, Sheng Wang, Yawen Hong, Renhua Gai, Wenxiang Hong, Bingbing Tang, Chunqin Lin, Xiaomeng Wang, Qiaojing Wang, Chao Chen, Jiajia Wang, Qinjie Weng
Publikováno v:
Toxics, Vol 11, Iss 2, p 114 (2023)
Curcumol, a natural product isolated from the traditional Chinese medicine Rhizoma curcumae, possesses various potential therapeutic values in many diseases. However, evidence of its toxicological profile is currently lacking. In this study, a repeat
Externí odkaz:
https://doaj.org/article/c4c6262b7b874571a658fc9fff729638
Autor:
Lijun Yang, Jian Cao, Yiwen Du, Xunqi Zhang, Wenxiang Hong, Bowen Peng, Jiahe Wu, Qinjie Weng, Jiajia Wang, Jianqing Gao
Publikováno v:
Theranostics; 2024, Vol. 14 Issue 2, p879-891, 13p
Autor:
Wenxiang Hong, Liqian Song, Jincheng Wang, Qi Shi, Lijun Yang, Qiaojun He, Jiajia Wang, Yanfei Shao, Bo Yang, Qinjie Weng, Lulu Zhang, Chunyan Fang, Ji Cao, Guifeng Hao, Zhaoxu Yang, Yueping Qiu, Jiaying Wang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Optineurin (OPTN) has important functions in diverse biological processes and diseases, but its effect on dendritic cell (DC) differentiation and functionality remains elusive. Here we show that OPTN is upregulated in human and mouse DC maturation, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c14d8a98ff9819363d86bb256a05e0
https://doaj.org/article/ed01766df50a46f3ab6099205d41690e
https://doaj.org/article/ed01766df50a46f3ab6099205d41690e
Publikováno v:
Frontiers in pharmacology. 13
CCR7, collaborated with its ligands CCL19 and CCL21, controls extensive migratory events in the immune system. CCR7-bearing dendritic cells can swarm into T-cell zones in lymph nodes, initiating the antigen presentation and T-cell response. Abnormal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e2801d7d3e907d489fc9b2b592a616
https://pubmed.ncbi.nlm.nih.gov/35281921
https://pubmed.ncbi.nlm.nih.gov/35281921
Autor:
Jinxin Che, Dan Li, Wenxiang Hong, Longling Wang, Yu Guo, Mingfei Wu, Jialiang Lu, Lexian Tong, Qinjie Weng, Jiajia Wang, Xiaowu Dong
Publikováno v:
European Journal of Medicinal Chemistry. 243:114732
The M2 polarized macrophages modulation has been described as a beneficial approach to facilitate the myelin repairing and inflammation microenvironment remodeling of multiple sclerosis (MS). Whereas, the M2 polarization involves complex mechanisms,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50fcf0c7858f7d708fb37118d8277e1
https://doi.org/10.1016/j.ejmech.2022.114732
https://doi.org/10.1016/j.ejmech.2022.114732