Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Wenwen Shangguan"'
Autor:
Xiaowan Li, Wenwen Shangguan, Xiaoqian Yang, Xiaoyue Hu, Yanan Li, Wenjie Zhao, Meiqing Feng, Jun Feng
Publikováno v:
Viruses, Vol 16, Iss 5, p 760 (2024)
Acinetobacter baumannii has developed multiple drug resistances, posing a significant threat to antibiotic efficacy. LysECD7, an endolysin derived from phages, could be a promising therapeutic agent against multi-drug resistance A. baumannii. In this
Externí odkaz:
https://doaj.org/article/fba039bb27e34a72b1b28b0f4d0f8afe
Autor:
Jianguang Lu, Wenwen Shangguan, Jin-Hua Zhang, Meiqing Feng, Mengxin Qian, Qingbin Zhang, Yapeng Wang, Jun Feng
Publikováno v:
Bioconjugate Chemistry. 32:615-625
Human Interleukin 2 (IL-2) has already achieved impressive results as a therapeutic agent for cancer and autoimmune diseases. However, one of the limitations associated with the clinical application of IL-2 is its short half-life owing to rapid clear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4ecfc0f921272aeaa062a70a224970
https://doi.org/10.1021/acs.bioconjchem.1c00062
https://doi.org/10.1021/acs.bioconjchem.1c00062
Autor:
Jinhua Zhang, Hongjiang Xu, Yuanzhen Dong, Jun Feng, Minwei Chen, Wenjie Zhao, Tang Hanqing, Wenwen Shangguan
Publikováno v:
The Journal of Antibiotics. 74:133-142
Based on NH2-(AEEA)5-amphotericin B (DMR005; AEEA is 8-amino-3,6-dioxaoctanoic acid), a series of novel esterified and acylated derivatives of DMR005 were synthesized. These derivatives were evaluated for their antifungal activities using the broth d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bf559efc097b19369cb0e1c14b650b5
https://doi.org/10.1038/s41429-020-00365-3
https://doi.org/10.1038/s41429-020-00365-3
Autor:
Wenjie Zhao, Hongjiang Xu, Wenwen Shangguan, Minwei Chen, Yuanzhen Dong, Jun Feng, Jinhua Zhang, You Zhang
Publikováno v:
European journal of medicinal chemistry. 211
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101f9424bf58e4d69110ee22456d11ae
https://pubmed.ncbi.nlm.nih.gov/33360798
https://pubmed.ncbi.nlm.nih.gov/33360798
Autor:
Wenjie Zhao, Yong Wu, Yapeng Wang, Jianguang Lu, Qingbin Zhang, Mengxin Qian, Jun Feng, Wenwen Shangguan
Publikováno v:
European Journal of Pharmacology. 904:174152
Antigen-binding fragments (Fabs) are preferred alternatives to antibodies for medical application, whereas their short half-lives limit therapeutic effectiveness. Albumin binding domain (ABD) with high affinity for albumin possesses a great potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfe92c6121285c5ed80d8ae75347369
https://doi.org/10.1016/j.ejphar.2021.174152
https://doi.org/10.1016/j.ejphar.2021.174152