Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Wentian Yang"'
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-19 (2022)
Abstract Skeletal development and homeostasis in mammals are modulated by finely coordinated processes of migration, proliferation, differentiation, and death of skeletogenic cells originating from the mesoderm and neural crest. Numerous molecular me
Externí odkaz:
https://doaj.org/article/e65a89914ce649948cd6bbe051d5f671
Autor:
Lijun Wang, Huiliang Yang, Jiahui Huang, Shaopeng Pei, Liyun Wang, Jian Q. Feng, Dian Jing, Hu Zhao, Henry M. Kronenberg, Douglas C. Moore, Wentian Yang
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-11 (2021)
Abstract The maturation and function of osteoblasts (OBs) rely heavily on the reversible phosphorylation of signaling proteins. To date, most of the work in OBs has focused on phosphorylation by tyrosyl kinases, but little has been revealed about dep
Externí odkaz:
https://doaj.org/article/352a3e3dbf384d0f86f567f4fe9415d2
Autor:
Charlène Niogret, S. M. Shahjahan Miah, Giorgia Rota, Nicolas P. Fonta, Haiping Wang, Werner Held, Walter Birchmeier, Veronica Sexl, Wentian Yang, Eric Vivier, Ping-Chih Ho, Laurent Brossay, Greta Guarda
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The phosphatase Shp-2 was implicated in NK cell education due to its reported association with inhibitory receptors, but its function in this context is unclear. Here the authors show that Shp-2 is not required for NK cell function, but is necessary
Externí odkaz:
https://doaj.org/article/41cf5051ab934c2b9282cb0fc85ec566
Autor:
S. M. Shahjahan Miah, Chathuraka T. Jayasuriya, Alexander I. Salter, Emma C. Reilly, Céline Fugere, Wentian Yang, Qian Chen, Laurent Brossay
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The ubiquitously expressed tyrosine phosphatase Src homology region 2 domain-containing phosphatase-2 (SHP-2, encoded by Ptpn11) is required for constitutive cellular processes including proliferation, differentiation, and the regulation of immune re
Externí odkaz:
https://doaj.org/article/50a394ed81284e4b95a06f6f2878920e
Autor:
Alexander Vesprey, Wentian Yang
Publikováno v:
Bio-Protocol, Vol 6, Iss 12 (2016)
Although it is possible to use a tartrate-resistant acid phosphatase (TRAP) stain to assist in identifying osteoclasts, a separate method is needed to determine the bone resorption activity of osteoclasts. Since osteoclasts leave “pits” after bon
Externí odkaz:
https://doaj.org/article/5570ae72f22841f6a68200473c0cc3ee
Publikováno v:
PLoS Genetics, Vol 10, Iss 5, p e1004364 (2014)
Loss of PTPN11/SHP2 in mice or in human metachondromatosis (MC) patients causes benign cartilage tumors on the bone surface (exostoses) and within bones (enchondromas). To elucidate the mechanisms underlying cartilage tumor formation, we investigated
Externí odkaz:
https://doaj.org/article/161d62f3c19a435bb3f2b0e5cc792c22
Publikováno v:
Bone Research
Bone Research, Vol 10, Iss 1, Pp 1-19 (2022)
Bone Research, Vol 10, Iss 1, Pp 1-19 (2022)
Skeletal development and homeostasis in mammals are modulated by finely coordinated processes of migration, proliferation, differentiation, and death of skeletogenic cells originating from the mesoderm and neural crest. Numerous molecular mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e55bc37b930ccb999e5c3db24753d20
https://pubmed.ncbi.nlm.nih.gov/35091552
https://pubmed.ncbi.nlm.nih.gov/35091552
Autor:
Liyun Wang, Lijun Wang, Henry M. Kronenberg, Hu Zhao, Huiliang Yang, Douglas C. Moore, Wentian Yang, Shaopeng Pei, Dian Jing, Jiahui Huang, Jian Q. Feng
Publikováno v:
Bone Research
Bone Research, Vol 9, Iss 1, Pp 1-11 (2021)
Bone Research, Vol 9, Iss 1, Pp 1-11 (2021)
The maturation and function of osteoblasts (OBs) rely heavily on the reversible phosphorylation of signaling proteins. To date, most of the work in OBs has focused on phosphorylation by tyrosyl kinases, but little has been revealed about dephosphoryl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657b2118cfef1a27724e7946bf3ee39f
https://doi.org/10.1038/s41413-020-00129-7
https://doi.org/10.1038/s41413-020-00129-7
Autor:
Wentian Yang, Peter J. Quesenberry, Hu Zhao, Lijun Wang, Weibiao Cao, Jiahui Huang, Cynthia L. Jackson, Jerry D-H Yue, Douglas C. Moore, Yuhong Wang
Publikováno v:
The FASEB Journal. 35
The protein tyrosine phosphatase SHP2, encoded by PTPN11, is ubiquitously expressed and essential for the development and/or maintenance of multiple tissues and organs. SHP2 is involved in gastrointestinal (GI) epithelium development and homeostasis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c12f00d359f57b8dffb5bf52c4457b6
https://doi.org/10.1096/fj.202001091r
https://doi.org/10.1096/fj.202001091r
Publikováno v:
RNA (New York, N.Y.).
Fluorescent reporters have been widely used in modern biology as a powerful tool in cell lineage tracing during development and in studying the pathogenesis of diseases. RNAscope is a recently developed RNA in situ hybridization method with high spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6ba68818e0a8b959443d39b5991c35
https://pubmed.ncbi.nlm.nih.gov/33277438
https://pubmed.ncbi.nlm.nih.gov/33277438