Zobrazeno 1 - 10
of 424
pro vyhledávání: '"Wenrong Xu"'
Autor:
Linru Shi, Yuyan Hu, Houcheng Zeng, Hui Shi, Wenrong Xu, Yaoxiang Sun, Hong Chu, Cheng Ji, Hui Qian
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Renal interstitial fibrosis (RIF) is a prevalent consequence of chronic renal diseases, characterized by excessive extracellular matrix (ECM) deposition. A Disintegrin and Metalloprotease 17 (ADAM17), a transmembrane metalloproteinase, plays
Externí odkaz:
https://doaj.org/article/e543d179b91747d2a8f8814e73f3dc6a
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Diabetic kidney disease (DKD), a chronic kidney disease, is characterized by progressive fibrosis caused due to persistent hyperglycemia. The development of fibrosis in DKD determines the patient prognosis, but no particularly effective trea
Externí odkaz:
https://doaj.org/article/45e72714c7c74a2e860d4ab76a599d91
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract This study aims to evaluate the safety of Alprazolam by analyzing the FAERS database, provide data analysis for monitoring adverse drug reactions. This research encompasses adverse event (AE) reports related to Alprazolam from the first quar
Externí odkaz:
https://doaj.org/article/e2f78a8b10e54e3e811cd17a9cf48454
Autor:
Fengtian Sun, Yuntong Sun, Xiaoling Wang, Junyan Zhu, Shenyuan Chen, Yifan Yu, Mengyao Zhu, Wenrong Xu, Hui Qian
Publikováno v:
Bioactive Materials, Vol 33, Iss , Pp 444-459 (2024)
Diabetic retinopathy (DR) is a leading cause of blindness worldwide with limited treatment options. Mesenchymal stem cell-derived small extracellular vesicles (MSC-sEVs) hold promise as a cell-free therapy for retinal diseases. In this study, we pres
Externí odkaz:
https://doaj.org/article/5dc3bb7682334fc1bc2c5fe338a67e66
Autor:
Xueyan Zang, Rongrong Wang, Ziyi Wang, Shuangyang Qiu, Fan Zhang, Le Zhou, Ye Shen, Hui Qian, Wenrong Xu, Jiajia Jiang
Publikováno v:
Translational Oncology, Vol 45, Iss , Pp 101969- (2024)
Background: Exosomes, one of small extracellular vesicles, play a vital role in cell to cell communication and contribute to the advancement of tumors through their cargo molecules. Exosomal circRNAs have emerged as significant players in various typ
Externí odkaz:
https://doaj.org/article/fb45c0b1ccc04c4c9a66cc18fe33b189
Publikováno v:
npj Regenerative Medicine, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Renal interstitial fibrosis (RIF) is a fundamental pathological feature of chronic kidney disease (CKD). However, toxicity and poor renal enrichment of fibrosis inhibitors limit their further applications. In this study, a platform for CKD t
Externí odkaz:
https://doaj.org/article/e7975e1dc9fb40d592e7cd43753b428f
Autor:
Peiwen Fu, Yumeng Guo, Yanan Luo, Michael Mak, Jianguo Zhang, Wenrong Xu, Hui Qian, Zhimin Tao
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract MicroRNA (miRNA) delivery by extracellular vesicles (EVs) has recently inspired tremendous developments in cancer treatments. However, hybridization between miRNA and its target mRNA is still difficult to be imaged in vivo to assess the ther
Externí odkaz:
https://doaj.org/article/b4b2a404cc824518bf039cba06cc8c80
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-25 (2023)
Abstract Exosomal circRNA serves a novel genetic information molecule, facilitating communication between tumor cells and microenvironmental cells, such as immune cells, fibroblasts, and other components, thereby regulating critical aspects of cancer
Externí odkaz:
https://doaj.org/article/4d570b3896eb40cf9ff46fee73af2f8d
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Extracellular vesicles (EVs), a cluster of cell-secreted lipid bilayer nanoscale particles, universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past years, increasing attention have been paid to the im
Externí odkaz:
https://doaj.org/article/3fad29d13a6b4a9297a7cb055e8845cc
Autor:
Hong Zhang, Rui Chen, Xiaohong Xu, Minxing Yang, Wenrong Xu, Shoukui Xiang, Long Wang, Xiaohong Jiang, Fei Hua, Xiaolin Huang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background The impact of metabolically healthy obesity (MHO) on kidney dysfunction remains debatable. Moreover, few studies have focused on the early stages of kidney dysfunction indicated by hyperfiltration and mildly reduced eGFR. Thus, we
Externí odkaz:
https://doaj.org/article/0bac5e01cf644f1188481082ca7f10f1