Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Wenquan Ou"'
Autor:
Xiaode Qiu, Guangqian Quan, Wenquan Ou, Pengfei Wang, Xing Huang, Xinhua Li, Yufan Shen, Weifeng Yang, Jian Wang, Xiaohua Wu
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: The pathogenic genes of colorectal cancer (CRC) have not yet been fully elucidated, and there is currently a lack of effective therapeutic targets. This study used bioinformatics methods to explore and experimentally validate the most val
Externí odkaz:
https://doaj.org/article/35c397ee9dfd4d56b4b7016e9b40a25f
Autor:
Wenquan Ou, Samantha Stewart, Alisa White, Elyahb A. Kwizera, Jiangsheng Xu, Yuanzhang Fang, James G. Shamul, Changqing Xie, Suliat Nurudeen, Nikki P. Tirada, Xiongbin Lu, Katherine H. R. Tkaczuk, Xiaoming He
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Cryosurgery can represent a therapeutic option for breast cancer treatment. Here the authors report a strategy combining cryosurgery with cold-responsive nanoparticles loaded with the chemotherapeutic drug irinotecan and PD-L1-targeting siRNA, induci
Externí odkaz:
https://doaj.org/article/c0eff733099941e69d7c0e80f527ab61
Autor:
Bin Jiang, Alisa White, Wenquan Ou, Sarah Van Belleghem, Samantha Stewart, James G. Shamul, Shaik O. Rahaman, John P. Fisher, Xiaoming He
Publikováno v:
Bioactive Materials, Vol 16, Iss , Pp 346-358 (2022)
The conventional approach for fabricating polydimethylsiloxane (PDMS) microfluidic devices is a lengthy and inconvenient procedure and may require a clean-room microfabrication facility often not readily available. Furthermore, living cells can't sur
Externí odkaz:
https://doaj.org/article/3103fd262c1a48e987edcb83ef399fbd
Rock inhibitor may compromise human induced pluripotent stem cells for cardiac differentiation in 3D
Autor:
Bin Jiang, Wenquan Ou, James G. Shamul, Hao Chen, Sarah Van Belleghem, Samantha Stewart, Zhenguo Liu, John P. Fisher, Xiaoming He
Publikováno v:
Bioactive Materials, Vol 9, Iss , Pp 508-522 (2022)
Cardiomyocytes differentiated from human induced pluripotent stem cells (iPSCs) are valuable for the understanding/treatment of the deadly heart diseases and their drug screening. However, the very much needed homogeneous 3D cardiac differentiation o
Externí odkaz:
https://doaj.org/article/22f906680eb94587a1c1c05ada832df2
Publikováno v:
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background The operative results of different approaches for the laparoscopic intersphincteric resection (LAISR) of low rectal cancer vary, and the patient characteristics associated with the best outcomes for each procedure have not been re
Externí odkaz:
https://doaj.org/article/790e1600ca934e5593c99afb05a16ef4
Autor:
Bin Jiang, Weijie Li, Samantha Stewart, Wenquan Ou, Baolin Liu, Pierre Comizzoli, Xiaoming He
Publikováno v:
Bioactive Materials, Vol 6, Iss 12, Pp 4377-4388 (2021)
Human induced pluripotent stem cells (hiPSCs) possess tremendous potential for tissue regeneration and banking hiPSCs by cryopreservation for their ready availability is crucial to their widespread use. However, contemporary methods for hiPSC cryopre
Externí odkaz:
https://doaj.org/article/3eda6b804be64982bbe33f14ac9917e4
Autor:
Wenquan Ou, Kang Sik Nam, Dae Hoon Park, Jungho Hwang, Sae Kwang Ku, Chul Soon Yong, Jong Oh Kim, Jeong Hoon Byeon
Publikováno v:
Nano-Micro Letters, Vol 12, Iss 1, Pp 1-19 (2020)
Abstract Because of enhanced efficacy and lower side effects, cancer immunotherapies have recently been extensively investigated in clinical trials to overcome the limitations of conventional cancer monotherapies. Although engineering attempts have b
Externí odkaz:
https://doaj.org/article/3d3f05f97367416f975333345c09149a
Autor:
Zar Chi Soe, Bijay Kumar Poudel, Hanh Thuy Nguyen, Raj Kumar Thapa, Wenquan Ou, Milan Gautam, Kishwor Poudel, Sung Giu Jin, Jee-Heon Jeong, Sae Kwang Ku, Han-Gon Choi, Chul Soon Yong, Jong Oh Kim
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 14, Iss 1, Pp 40-51 (2019)
Folate-targeting self-assembled nanoparticles (NPs) using biocompatible and biodegradable natural polymers chitosan (Cs) and chondroitin sulfate (Chs) were developed to address the major challenge in cancer treatment, the selective delivery of nanopa
Externí odkaz:
https://doaj.org/article/67b2f3ac3ac34daa9f4d169f83b42949
Autor:
Zar Chi Soe, Wenquan Ou, Milan Gautam, Kishwor Poudel, Bo Kyun Kim, Le Minh Pham, Cao Dai Phung, Jee-Heon Jeong, Sung Giu Jin, Han-Gon Choi, Sae Kwang Ku, Chul Soon Yong, Jong Oh Kim
Publikováno v:
Pharmaceutics, Vol 11, Iss 11, p 562 (2019)
In this study, we investigated the active targeted delivery of a hydrophobic drug, paclitaxel (PTX), via receptor-mediated endocytosis by folate receptors expressed on cancer cells using a protein-based nanoparticle system. PTX was loaded on zein nan
Externí odkaz:
https://doaj.org/article/31fcd111e6de4ac69ef9df2a2d212a16
Autor:
Zar Chi Soe, Jun Bum Kwon, Raj Kumar Thapa, Wenquan Ou, Hanh Thuy Nguyen, Milan Gautam, Kyung Taek Oh, Han-Gon Choi, Sae Kwang Ku, Chul Soon Yong, Jong Oh Kim
Publikováno v:
Pharmaceutics, Vol 11, Iss 2, p 63 (2019)
In this study, a transferrin (Tf)-conjugated polymeric nanoparticle was developed for the targeted delivery of the chemotherapeutic agent doxorubicin (Dox) in order to overcome multi-drug resistance in cancer treatment. Our objective was to improve D
Externí odkaz:
https://doaj.org/article/cf38fda9d6084500b7db97c43e006c6f