Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Wenqing Shui"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Many software suites and spectral libraries have been developed for DIA proteomics data analysis. Here, the authors create benchmark data sets to evaluate four commonly used software tools combined with seven spectral libraries in both global proteom
Externí odkaz:
https://doaj.org/article/1ddc8e335f7b40868b2f2f3f64f66a60
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The coverage and throughput of data-independent acquisition (DIA)-based phosphoproteomics is limited by its dependence on experimental spectral libraries. Here the authors develop a DIA workflow based on in silico spectral libraries generated by a no
Externí odkaz:
https://doaj.org/article/70e7e24906674cd4a67e2516deeb2150
Autor:
Dehua Yang, Qingtong Zhou, Viktorija Labroska, Shanshan Qin, Sanaz Darbalaei, Yiran Wu, Elita Yuliantie, Linshan Xie, Houchao Tao, Jianjun Cheng, Qing Liu, Suwen Zhao, Wenqing Shui, Yi Jiang, Ming-Wei Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-27 (2021)
Abstract As one of the most successful therapeutic target families, G protein-coupled receptors (GPCRs) have experienced a transformation from random ligand screening to knowledge-driven drug design. We are eye-witnessing tremendous progresses made r
Externí odkaz:
https://doaj.org/article/5105491674ff49e3b4dcfd70db593de2
Autor:
Hui Li, Jie Yang, Cuiping Tian, Min Diao, Quan Wang, Simeng Zhao, Shanshan Li, Fangzhi Tan, Tian Hua, Ya Qin, Chao-Po Lin, Dylan Deska-Gauthier, Garth J. Thompson, Ying Zhang, Wenqing Shui, Zhi-Jie Liu, Tong Wang, Guisheng Zhong
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Despite the importance of G-protein-coupled receptors in many cellular functions, their intracellular organisation is largely unknown. The authors identified periodically repeating clusters of cannabinoid receptor 1 hotspots within neuronal axons tha
Externí odkaz:
https://doaj.org/article/16d642a130464ca1a75800a5fd41828b
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
G protein–coupled receptors (GPCRs) are a protein superfamily comprising >800 members that regulate numerous cellular and physiologic responses. GPCRs represent the largest class of therapeutic targets with implications in various diseases. Althoug
Externí odkaz:
https://doaj.org/article/302ae59179c04fc4bfb5c98b463408bb
Autor:
Bingjie Zhang, Simeng Zhao, Dehua Yang, Yiran Wu, Ye Xin, Haijie Cao, Xi-Ping Huang, Xiaoqing Cai, Wen Sun, Na Ye, Yueming Xu, Yao Peng, Suwen Zhao, Zhi-Jie Liu, Guisheng Zhong, Ming-Wei Wang, Wenqing Shui
Publikováno v:
ACS Central Science, Vol 6, Iss 2, Pp 213-225 (2020)
Externí odkaz:
https://doaj.org/article/f913f83afcbe47449810dd570d7d282f
Autor:
Ronghui Lou, Pan Tang, Kang Ding, Shanshan Li, Cuiping Tian, Yunxia Li, Suwen Zhao, Yaoyang Zhang, Wenqing Shui
Publikováno v:
iScience, Vol 23, Iss 3, Pp - (2020)
Summary: Data-independent acquisition mass spectrometry (DIA-MS) is a powerful technique that enables relatively deep proteomic profiling with superior quantification reproducibility. DIA data mining predominantly relies on a spectral library of suff
Externí odkaz:
https://doaj.org/article/70294ed79e2148b7900943eb9b484b68
Autor:
Qingtong Zhou, Wanjing Guo, Antao Dai, Xiaoqing Cai, Márton Vass, Chris de Graaf, Wenqing Shui, Suwen Zhao, Dehua Yang, Ming-Wei Wang
Publikováno v:
Biomolecules, Vol 11, Iss 7, p 929 (2021)
Allosteric modulators have emerged with many potential pharmacological advantages as they do not compete the binding of agonist or antagonist to the orthosteric sites but ultimately affect downstream signaling. To identify allosteric modulators targe
Externí odkaz:
https://doaj.org/article/e0f406affb7b466fa714fe033544fada
Autor:
Bingjie Zhang, Simeng Zhao, Dehua Yang, Yiran Wu, Ye Xin, Haijie Cao, Xi-Ping Huang, Xiaoqing Cai, Wen Sun, Na Ye, Yueming Xu, Yao Peng, Suwen Zhao, Zhi-Jie Liu, Guisheng Zhong, Ming-Wei Wang, Wenqing Shui
Publikováno v:
ACS Central Science, Vol 6, Iss 5, Pp 823-824 (2020)
Externí odkaz:
https://doaj.org/article/8bc1744993334899930c65156a769afb
Publikováno v:
eLife, Vol 6 (2017)
The tubular network is a critical part of the endoplasmic reticulum (ER). The network is shaped by the reticulons and REEPs/Yop1p that generate tubules by inducing high membrane curvature, and the dynamin-like GTPases atlastin and Sey1p/RHD3 that con
Externí odkaz:
https://doaj.org/article/cd55ab4a35204496a6acbcf56931b610