Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Wenping Dai"'
Autor:
George W. Elgart, Niramol Savaraj, Yingjie Wei, Yen Chiu Lin-Lee, M. Tien Kuo, Sheng Zhao, Feyruz V. Rassool, Xinlin Yang, Lynn G. Feun, Wenping Dai
Publikováno v:
Gene. 372:44-52
DNA amplification plays important roles in the development of drug resistance and tumor progression. One mechanism of DNA amplification involves the breakage-fusion-bridge (BFB) cycle. We previously reported that in Chinese hamster ovary (CHO) cell l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de6ad867a79ee86232d5ac14d4ade77
https://doi.org/10.1016/j.gene.2005.12.024
https://doi.org/10.1016/j.gene.2005.12.024
Autor:
Robert H. Moore, Tuan M. Tran, Veronica Godines, Richard B. Clark, Jacqueline Friedman, David Vaughan, Brian J. Knoll, Wenping Dai, Ellen E. Millman
Publikováno v:
Journal of Biological Chemistry. 281:7684-7692
There is considerable evidence for the role of carboxyl-terminal serines 355, 356, and 364 in G protein-coupled receptor kinase (GRK)-mediated phosphorylation and desensitization of beta(2)-adrenergic receptors (beta(2)ARs). In this study we used rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41736d089ac8983a54db60dd30919c91
https://doi.org/10.1074/jbc.m500328200
https://doi.org/10.1074/jbc.m500328200
Publikováno v:
British Journal of Pharmacology. 147:249-259
Activated beta2-adrenoceptors are rapidly desensitized by phosphorylation of Ser262 by protein kinase A (PKA) and of Ser355,356 by G-protein-coupled receptor kinase (GRK). We sought to determine whether the phosphorylation and subsequent dephosphoryl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7afd39448dfd3d6e480d28363211accf
https://doi.org/10.1038/sj.bjp.0706551
https://doi.org/10.1038/sj.bjp.0706551
Autor:
Ellen E. Millman, Richard B. Clark, Robert H. Moore, Brian J. Knoll, Wenping Dai, Estrella Alpizar-Foster, Jennifer L. Rosenfeld, David Vaughan, Jacqueline Nguyen
Publikováno v:
British Journal of Pharmacology. 141:277-284
We have investigated the role of G protein-coupled receptor kinase 5 (GRK5) in the regulation of endosome sorting of human β2-adrenoceptors. Expressing GRK5 at a high level significantly increased the extent of internalization of wild-type β2-adren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac2576a5189855ce8d7ee2730250d8bc
https://doi.org/10.1038/sj.bjp.0705504
https://doi.org/10.1038/sj.bjp.0705504
Autor:
P. D. Stahl, S. Hoffenberg, Wenping Dai, H. S. Hall, L. Nikolova, Brian J. Knoll, M. A. Barbieri, R. E. Baughn, Burton F. Dickey, X. Liu, Alejandro Aballay
Publikováno v:
Journal of Biological Chemistry. 275:24661-24669
The ras-related GTPase rab5 is rate-limiting for homotypic early endosome fusion. We used a yeast two-hybrid screen to identify a rab5 interacting protein, rab5ip. The cDNA sequence encodes a ubiquitous 75-kDa protein with an N-terminal transmembrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3ddf80d763d90d64f8f0c580094ff9
https://doi.org/10.1074/jbc.m909600199
https://doi.org/10.1074/jbc.m909600199
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
The nuclease of Serratia marcescens is an extracellular protein encoded by the nucA gene. Pre-nuclease carries a typical 21-amino-acid N-terminal signal sequence that interacts with the Sec machinery to allow the translocation of nuclease to the peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2843be5098b5b68089f0e747e0b7bbea
https://doi.org/10.1099/13500872-145-5-1209
https://doi.org/10.1099/13500872-145-5-1209
Publikováno v:
European Journal of Pharmacology. 369:113-123
Agonist-activated beta2-adrenoceptors rapidly internalize and then recycle to the cell surface, however chronic agonist eventually causes receptor downregulation. To characterize beta2-adrenoceptor trafficking kinetics and intracellular sorting durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06bf5d8f1d13bbf827351b03c139207
https://doi.org/10.1016/s0014-2999(99)00055-2
https://doi.org/10.1016/s0014-2999(99)00055-2
Publikováno v:
Journal of Bacteriology. 180:2262-2264
A family of mutants overexpressing the Serratia marcescens extracellular nuclease has been known for decades. A number of these alleles are characterized here at the molecular level, and the mutant genes are identified, yielding a likely model for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73712b318157bca95d3af12895ade462
https://doi.org/10.1128/jb.180.8.2262-2264.1998
https://doi.org/10.1128/jb.180.8.2262-2264.1998
Publikováno v:
The Journal of biological chemistry. 280(31)
Expression of the gamma-glutamylcysteine synthetase heavy subunit (gamma-GCSh), which encodes the rate-limiting enzymes for glutathione biosynthesis, is regulated by many cytotoxic agents. Moreover, gamma-GCSh mRNA expression is elevated in colorecta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da548620beb68dee0109e4b1a166a42
https://pubmed.ncbi.nlm.nih.gov/15946948
https://pubmed.ncbi.nlm.nih.gov/15946948
Publikováno v:
Journal of cell science. 117(Pt 15)
The pericentriolar recycling endosome (RE) may be an alternative compartment through which some beta2-adrenergic receptors (beta2ARs) recycle from early endosomes to the cell surface during prolonged exposure to agonist. For the transferrin receptor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439727e2a62ed7dfa20477460bd4f25f
https://pubmed.ncbi.nlm.nih.gov/15190120
https://pubmed.ncbi.nlm.nih.gov/15190120