Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Wenmao Huang"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Titin N2B unique sequence (N2B-us) is a 572 amino acid sequence that acts as an elastic spring to regulate muscle passive elasticity. It is thought to lack stable tertiary structures and is a force-bearing region that is regulated by mechani
Externí odkaz:
https://doaj.org/article/76be120cb7bd4727bbca2eb7ffe8917a
Publikováno v:
APL Bioengineering, Vol 8, Iss 1, Pp 016114-016114-11 (2024)
α-Synuclein aggregation is a common trait in synucleinopathies, including Parkinson's disease. Being an unstructured protein, α-synuclein exists in several distinct conformational intermediates, contributing to both its function and pathogenesis. H
Externí odkaz:
https://doaj.org/article/bf6630149bac433a8918b1693654d2db
Actin polymerisation and crosslinking drive left-right asymmetry in single cell and cell collectives
Autor:
Yee Han Tee, Wei Jia Goh, Xianbin Yong, Hui Ting Ong, Jinrong Hu, Ignacius Yan Yun Tay, Shidong Shi, Salma Jalal, Samuel F. H. Barnett, Pakorn Kanchanawong, Wenmao Huang, Jie Yan, Yong Ann Ben Lim, Visalatchi Thiagarajan, Alex Mogilner, Alexander D. Bershadsky
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
In this work, the authors identify regulators of actin filament assembly involved in chiral organisation of the actin cytoskeleton in single cells and chiral alignment of cells in groups. This provides insights into how actin-driven chirality underli
Externí odkaz:
https://doaj.org/article/a04bac554ea94ed8891bb4b8355d7cab
Autor:
Aravindh Subramani, Weiyingqi Cui, Yuanyuan Zhang, Tomas Friman, Zhihai Zhao, Wenmao Huang, Pedro Fonseca, Weng-Onn Lui, Vani Narayanan, Justyna Bobrowska, Małgorzata Lekka, Jie Yan, Daniel E. Conway, Lars Holmgren
Publikováno v:
Cells, Vol 12, Iss 13, p 1682 (2023)
The spread of tumor cells and the formation of distant metastasis remain the main causes of mortality in cancer patients. However, the mechanisms governing the release of cells from micro-environmental constraints remain unclear. E-cadherin negativel
Externí odkaz:
https://doaj.org/article/9df467c8a30547e1b7d9973ac51c9dde
Publikováno v:
ACS Sensors. 8:704-711
Publikováno v:
Journal of the American Chemical Society. 144:16808-16818
The adhesions between Gram-positive bacteria and their hosts are exposed to varying magnitudes of tensile forces. Here, using an ultrastable magnetic tweezer-based single-molecule approach, we show the catch-bond kinetics of the prototypical adhesion
Autor:
Holmgren, Aravindh Subramani, Weiyingqi Cui, Yuanyuan Zhang, Tomas Friman, Zhihai Zhao, Wenmao Huang, Pedro Fonseca, Weng-Onn Lui, Vani Narayanan, Justyna Bobrowska, Małgorzata Lekka, Jie Yan, Daniel E. Conway, Lars
Publikováno v:
Cells; Volume 12; Issue 13; Pages: 1682
The spread of tumor cells and the formation of distant metastasis remain the main causes of mortality in cancer patients. However, the mechanisms governing the release of cells from micro-environmental constraints remain unclear. E-cadherin negativel
Autor:
Jingjing Wang, Yuheng Fu, Wenmao Huang, Ritusree Biswas, Avinanda Banerjee, Joshua A. Broussard, Zhihai Zhao, Dongmei Wang, Glen Bjerke, Srikala Raghavan, Jie Yan, Kathleen J. Green, Rui Yi
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Stiffness and actomyosin contractility are intrinsic mechanical properties of animal cells required for the shaping of tissues. However, whether tissue stem cells (SCs) and progenitors located within SC niche have different mechanical properties that
Autor:
Florian Rouaud, Wenmao Huang, Arielle Flinois, Kunalika Jain, Ekaterina Vasileva, Thomas Di Mattia, Marine Mauperin, David A.D. Parry, Vera Dugina, Christine Chaponnier, Isabelle Méan, Sylvie Montessuit, Annick Mutero-Maeda, Jie Yan, Sandra Citi
Publikováno v:
Journal of Cell Biology. 222
The mechanisms that regulate the spatial sorting of nonmuscle myosins-2 (NM2) isoforms and couple them mechanically to the plasma membrane are unclear. Here we show that the cytoplasmic junctional proteins cingulin (CGN) and paracingulin (CGNL1) inte
Autor:
Chaoyu Fu, Wenmao Huang, Qingnan Tang, Minghui Niu, Shiwen Guo, Tobias Langenhan, Gaojie Song, Jie Yan
Adhesion G protein-coupled receptors (aGPCRs) are a large family within the superfamily of G protein-coupled receptors involved in various physiological processes. One unique feature of aGPCRs is their long N-terminal extracellular regions (ECRs), wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e586436388bf69a583aef786bef1d41
https://doi.org/10.1101/2023.03.14.532526
https://doi.org/10.1101/2023.03.14.532526