Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Wenman, Zhang"'
Autor:
Jason G. Kettle, Sharan K. Bagal, Sue Bickerton, Michael S. Bodnarchuk, Scott Boyd, Jason Breed, Rodrigo J. Carbajo, Doyle J. Cassar, Atanu Chakraborty, Sabina Cosulich, Iain Cumming, Michael Davies, Nichola L. Davies, Andrew Eatherton, Laura Evans, Lyman Feron, Shaun Fillery, Emma S. Gleave, Frederick W. Goldberg, Lyndsey Hanson, Stephanie Harlfinger, Martin Howard, Rachel Howells, Anne Jackson, Paul Kemmitt, Gillian Lamont, Scott Lamont, Hilary J. Lewis, Libin Liu, Michael J. Niedbala, Christopher Phillips, Radek Polanski, Piotr Raubo, Graeme Robb, David M. Robinson, Sarah Ross, Matthew G. Sanders, Michael Tonge, Rebecca Whiteley, Stephen Wilkinson, Junsheng Yang, Wenman Zhang
Publikováno v:
Journal of Medicinal Chemistry. 65:6940-6952
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cb2a4d859543d18252213a2d5a9b54c
https://doi.org/10.1021/acs.jmedchem.2c00369
https://doi.org/10.1021/acs.jmedchem.2c00369
Autor:
Jason G, Kettle, Sharan K, Bagal, Sue, Bickerton, Michael S, Bodnarchuk, Scott, Boyd, Jason, Breed, Rodrigo J, Carbajo, Doyle J, Cassar, Atanu, Chakraborty, Sabina, Cosulich, Iain, Cumming, Michael, Davies, Nichola L, Davies, Andrew, Eatherton, Laura, Evans, Lyman, Feron, Shaun, Fillery, Emma S, Gleave, Frederick W, Goldberg, Lyndsey, Hanson, Stephanie, Harlfinger, Martin, Howard, Rachel, Howells, Anne, Jackson, Paul, Kemmitt, Gillian, Lamont, Scott, Lamont, Hilary J, Lewis, Libin, Liu, Michael J, Niedbala, Christopher, Phillips, Radek, Polanski, Piotr, Raubo, Graeme, Robb, David M, Robinson, Sarah, Ross, Matthew G, Sanders, Michael, Tonge, Rebecca, Whiteley, Stephen, Wilkinson, Junsheng, Yang, Wenman, Zhang
Publikováno v:
Journal of medicinal chemistry. 65(9)
KRAS is an archetypal high-value intractable oncology drug target. The glycine to cysteine mutation at codon 12 represents an Achilles heel that has now rendered this important GTPase druggable. Herein, we report our structure-based drug design appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c82ffa8ba3350b52cfb57034d024ef1
https://pubmed.ncbi.nlm.nih.gov/35471939
https://pubmed.ncbi.nlm.nih.gov/35471939