Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Wenlong Ren"'
Autor:
Wenmin Chen, Yue Wu, Chuanyu Yang, Wenlong Ren, Lei Hou, Huichun Liang, Tingyue Wu, Yanjie Kong, Jiao Wu, Yu Rao, Ceshi Chen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116972- (2024)
Breast cancer is one of the most prevalent malignancies affecting women worldwide, underscoring the urgent need for more effective and specific treatments. Proteolysis-targeting chimeras (PROTACs) have emerged as a promising strategy to develop new l
Externí odkaz:
https://doaj.org/article/6b83428d32704c5497033a2f9e81117e
Autor:
Tingyue Wu, Wenjing Liu, Hui Chen, Lei Hou, Wenlong Ren, Longlong Zhang, Jinhui Hu, Haijun Chen, Ceshi Chen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Triple-negative breast cancer (TNBC) is regarded as the deadliest subtype of breast cancer because of its high heterogeneity, aggressiveness, and limited treatment options. Toxoflavin has been reported to possess antitumor activity. In this
Externí odkaz:
https://doaj.org/article/02fe06658cf745deac4a18f1926b57bb
Autor:
Huan Fang, Wenlong Ren, Qiuxia Cui, Huichun Liang, Chuanyu Yang, Wenjing Liu, Xinye Wang, Xue Liu, Yujie Shi, Jing Feng, Ceshi Chen
Publikováno v:
eLife, Vol 12 (2023)
Anti-tumor drug resistance is a challenge for human triple-negative breast cancer (TNBC) treatment. Our previous work demonstrated that TNFAIP2 activates RAC1 to promote TNBC cell proliferation and migration. However, the mechanism by which TNFAIP2 a
Externí odkaz:
https://doaj.org/article/a47e4ac1b011411da2906874af50c308
Publikováno v:
Genes, Vol 11, Iss 11, p 1286 (2020)
In genome-wide association studies, linear mixed models (LMMs) have been widely used to explore the molecular mechanism of complex traits. However, typical association approaches suffer from several important drawbacks: estimation of variance compone
Externí odkaz:
https://doaj.org/article/18d3e1b7d24b40058f2764bb8b62c69d
Publikováno v:
Organic Letters; 7/26/2024, Vol. 26 Issue 29, p6174-6178, 5p
Autor:
Huan Fang, Wenlong Ren, Qiuxia Cui, Huichun Liang, Chuanyu Yang, Wenjing Liu, Xinye Wang, Xue Liu, Yujie Shi, Jing Feng, Ceshi Chen
SummaryAnti-tumor drug resistance is a challenge for triple-negative breast cancer treatment. Our previous work demonstrated that TNFAIP2 activates Rac1 to promote triple-negative breast cancer cell proliferation and migration. However, the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85743ea1123d21ae526d314da0e1f5ef
https://doi.org/10.1101/2023.04.17.537130
https://doi.org/10.1101/2023.04.17.537130
Autor:
Dewei Jiang, Ting Qiu, Junjiang Peng, Siyuan Li, null Tala, Wenlong Ren, Chuanyu Yang, Yi Wen, Chuan-Huizi Chen, Jian Sun, Yingying Wu, Rong Liu, Jun Zhou, Kongming Wu, Wen Liu, Xiaoyun Mao, Zhongmei Zhou, Ceshi Chen
Publikováno v:
Cell Death Differ
Y-box binding protein 1 (YB-1) is a well-known oncogene highly expressed in various cancers, including basal-like breast cancer (BLBC). Beyond its role as a transcription factor, YB-1 is newly defined as an epigenetic regulator involving RNA 5-methyl
Publikováno v:
European Journal of Organic Chemistry. 2020:1078-1083
Autor:
Yanjie Kong, Wenlong Ren, Huan Fang, Naseer Ali Shah, Yujie Shi, Dingyun You, Chengang Zhou, Dewei Jiang, Chuanyu Yang, Huichun Liang, Wenjin Liu, Luzhen Wang, Wenqiang Gan, Xing Wan, Fubing Li, Zhen Li, Ceshi Chen, Ni Xie
Publikováno v:
International journal of biological sciences. 18(5)
Basal-like breast cancer (BLBC) accounts for approximately 15% of all breast cancer cases, and patients with BLBC have a low survival rate. Our previous study demonstrated that the KLF5 transcription factor promotes BLBC cell proliferation and tumor
Publikováno v:
Organic Letters. 21:5967-5970
An efficient Pd-catalyzed hydrocarboxylation of alkenes with HCOOH is described. A wide variety of linear carboxylic acids bearing various functional groups can be obtained with excellent chemo- and regioselectivities under mild reaction conditions.