Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Wenlin Hao"'
Autor:
Wenlin Hao, Qinghua Luo, Inge Tomic, Wenqiang Quan, Tobias Hartmann, Michael D. Menger, Klaus Fassbender, Yang Liu
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Gut bacteria regulate brain pathology of Alzheimer’s disease (AD) patients and animal models; however, the underlying mechanism remains unclear. In this study, 3-month-old APP-transgenic female mice with and without knock-out of Il-17a gene were tr
Externí odkaz:
https://doaj.org/article/a7645f6f4bcd48c2a45ea25bcddf52f3
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Antiplatelet and anticoagulation drugs complicate acute gastrointestinal bleeding (GIB) patients. Limited data about the risk factors and patient management has been presented. This study explored the association between previous
Externí odkaz:
https://doaj.org/article/c161802ecb8341efbda0995cf73ea483
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Multiple sclerosis (MS) is a chronic autoimmune disease driven by T and B lymphocytes. The remyelination failure and neurodegeneration results in permanent clinical disability in MS patients. A desirable therapy should not only modulate the immune sy
Externí odkaz:
https://doaj.org/article/5696d1ab3df44435914c4f12942b80d1
Autor:
Laura Schnöder, Wenqiang Quan, Ye Yu, Inge Tomic, Qinghua Luo, Wenlin Hao, Guoping Peng, Dong Li, Klaus Fassbender, Yang Liu
Publikováno v:
The FASEB Journal. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7c764cd5fc3d3d29cdfee0ff24994ce
https://doi.org/10.1096/fj.202201512r
https://doi.org/10.1096/fj.202201512r
Autor:
Qinghua Luo, Laura Schnöder, Wenlin Hao, Kathrin Litzenburger, Yann Decker, Inge Tomic, Michael D. Menger, Yang Liu, Klaus Fassbender
Publikováno v:
Aging Cell. 21
Alzheimer's disease (AD), the most common cause of dementia in the elderly, is pathologically characterized by extracellular deposition of amyloid-β peptides (Aβ) and microglia-dominated inflammatory activation in the brain. p38α-MAPK is activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e682c1712fab623a63159b5c3a0d725e
https://doi.org/10.1111/acel.13679
https://doi.org/10.1111/acel.13679
Autor:
Tomomi Furihata, Wenqiang Quan, Wenlin Hao, Inge Tomic, Walter Schulz-Schäffer, Yang Liu, Klaus Fassbender, Michael D. Menger, Qinghua Luo
Publikováno v:
Glia. 69:1987-2005
Growing evidence indicates that innate immune molecules regulate microglial activation in Alzheimer's disease (AD); however, their effects on amyloid pathology and neurodegeneration remain inconclusive. Here, we conditionally deleted one allele of my
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f78961558a60e3dcf94aeeef63f176
https://doi.org/10.1002/glia.24007
https://doi.org/10.1002/glia.24007
Autor:
Laura Schnöder, Wenqiang Quan, Ye Yu, Inge Tomic, Qinghua Luo, Wenlin Hao, Guoping Peng, Dong Li, Klaus Fassbender, Yang Liu
Background: Alzheimer’s disease (AD) is pathologically characterized by extracellular deposition of amyloid β peptide (Aβ), intracellular neurofibrillary tangles (composed mainly of phosphorylated tau [p-tau]) and neuroinflammation. The pathogeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f4ad17b5185f4002bf6300e9df99a61
https://doi.org/10.21203/rs.3.rs-1696103/v1
https://doi.org/10.21203/rs.3.rs-1696103/v1
Autor:
Michael D. Menger, Wenlin Hao, Laura Schnöder, Kathrin Litzenburger, Qinghua Luo, Yann Decker, Inge Tomic, Klaus Fassbender, Yang Liu
Microglial activation is a hall marker of Alzheimer’s disease (AD); its pathogenic role and regulating mechanisms are unclear. p38α-MAPK, a stress-responding kinase, is activated in AD brain in early disease stages. In APP-transgenic mice, we dele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eba4a6ce5fcc751f49f71f0c524f078
https://doi.org/10.1101/2021.10.18.464870
https://doi.org/10.1101/2021.10.18.464870
Autor:
Schnöder, Laura, Wenqiang Quan, Ye Yu, Tomic, Inge, Qinghua Luo, Wenlin Hao, Guoping Peng, Dong Li, Fassbender, Klaus, Yang Liu
Publikováno v:
FASEB Journal; Feb2023, Vol. 37 Issue 2, p1-22, 22p
Autor:
Inge Tomic, Chun-Feng Liu, Wenlin Hao, Yiren Qin, Yang Liu, Yu Zhang, Michael D. Menger, Klaus Fassbender
Publikováno v:
Journal of Alzheimer's Disease. 65:243-263
Alzheimer's disease (AD) is a neurodegenerative disease pathologically characterized by extracellular amyloid-β (Aβ) deposits and intracellular neurofibrillary tangles (NFT) in many brain regions. NFT are primarily composed of hyperphosphorylated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb109e488046b9fb7b9bdf8d3e41b7fb
https://doi.org/10.3233/jad-180426
https://doi.org/10.3233/jad-180426