Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Wenlie Peng"'
Autor:
Rong Huang, Na Gao, Wenlie Peng, Jinhua Zhao, Longyan Zhao, Li Xu, Sensen Lai, Hong-Bo Qin, Mingyi Wu
Publikováno v:
Carbohydrate Polymers. 98:1514-1523
Fucosylated glycosaminoglycans (FGs) are complex glycosaminoglycans that exhibit potent anticoagulant activity. To study the relationship between molecular size and biological activity, oligosaccharides with (2,5)-anhydro-D-talose units at new reduci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d39883327bb6080d7b1c0b7d6963f2
https://doi.org/10.1016/j.carbpol.2013.07.063
https://doi.org/10.1016/j.carbpol.2013.07.063
Autor:
Wenlie Peng, Ning Huang, Zi Li, Na Gao, Zhigang Zhang, Yong-Tang Zheng, Wu Lian, Mingyi Wu, Chuang Xiao, Jinhua Zhao
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1830:4681-4691
Fucosylated glycosaminoglycan (FG) is a novel glycosaminoglycan with a chondroitin sulfate-like backbone and fucose sulfate branches. The aim of this study is to investigate the mechanism and structure-activity relationships (SAR) of FG for combating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b98a9f452c78d39b919834312822131
https://doi.org/10.1016/j.bbagen.2013.06.003
https://doi.org/10.1016/j.bbagen.2013.06.003
Autor:
Jinhua Zhao, Na Gao, Mingyi Wu, Jun Chen, Lutan Zhou, Wu Lian, Li Xu, Wenlie Peng, Chuang Xiao
Publikováno v:
Thrombosis research. 146
Fucosylated glycosaminoglycan (FG) is a structurally novel glycosaminoglycan derivative, and it has potent anticoagulant activity. Depolymerized FG (dFG) is a selective factor Xase (FXase, FIXa-FVIIIa complex) inhibitor and it has antithrombotic acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791ea7cc2b499808db05413acc368700
https://pubmed.ncbi.nlm.nih.gov/27611497
https://pubmed.ncbi.nlm.nih.gov/27611497
Publikováno v:
Chinese Journal of Chemistry. 19:263-267
The syntheses, characterizations and in vitro cytotoxities of seven soluble silver (I) compounds (1–7) with 2,2′-bipyridine (bpy), 5,5′-dimethyl-2,2′-bipyridine (dmbpy) and 1, 10-phenanthroline (phen) are described. Two of the complexes, [Ag(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::713b7b6e0c6548961e99d2c9fe8975b1
https://doi.org/10.1002/cjoc.20010190310
https://doi.org/10.1002/cjoc.20010190310
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:3876-3879
A series of water-soluble beta-carbolines, bearing a flexible amino side chain, was prepared and evaluated in vitro against a panel of human tumor cell lines. The N(9)-arylated alkyl substituted beta-carbolines represented the most interesting cytoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc985b959291703bcda1ae3b91aa9145
https://doi.org/10.1016/j.bmcl.2010.05.034
https://doi.org/10.1016/j.bmcl.2010.05.034
Publikováno v:
European Journal of Medicinal Chemistry. 45:2503-2515
In a continuing effort to develop novel beta-carbolines endowed with better pharmacological profiles, a series of beta-carboline derivatives were designed and synthesized based on the previously developed SARs. Cytotoxicities in vitro of these compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90825b87f7d3b6806192f98f428d5fe
https://doi.org/10.1016/j.ejmech.2010.02.036
https://doi.org/10.1016/j.ejmech.2010.02.036
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:3254-3258
A series of novel cholinesterase inhibitors, being composed of 4-[(diethylamino)methyl]-phenoxy and secondary amine which were linked with a different length alkyl chain, were designed and synthesized from the starting material p-hydroxybenzaldehyde.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52afd01f1f4b7d8486be45fb60c70bb4
https://doi.org/10.1016/j.bmcl.2010.04.059
https://doi.org/10.1016/j.bmcl.2010.04.059
Autor:
Wenlie Peng, Huacan Song, Chunming Ma, Zhenhua Ren, Rihui Cao, Buxi Shi, Zhiyong Chen, Wei Yi, Shaoxue Li
Publikováno v:
European Journal of Medicinal Chemistry. 45:1515-1523
The beta-carboline alkaloids have been characterized as a class of potential antitumor agents. To further enhance the cytotoxic potency and improve water solubility of beta-carboline, a series of new beta-carboline amino acid ester, beta-carboline am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7cb722a9a97bef71bc04da54b63ecd6
https://doi.org/10.1016/j.ejmech.2009.12.060
https://doi.org/10.1016/j.ejmech.2009.12.060
Publikováno v:
European Journal of Medicinal Chemistry. 44:1737-1744
A series of novel 4-alkylphenyl beta-aldehyde ketones and their derivatives were designed and synthesized on the basis of the chemical structures of Houttuynin and beta-lactam antibiotics. Antibacterial activities of these compounds were investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8121d2591339303571e778e0c0f508f8
https://doi.org/10.1016/j.ejmech.2008.03.010
https://doi.org/10.1016/j.ejmech.2008.03.010
Autor:
Xiangdong Guan, Manxiu Feng, Qifeng Wu, Jinbing Liu, Rihui Cao, Chunming Ma, Huacan Song, Wenlie Peng
Publikováno v:
European Journal of Medicinal Chemistry. 44:533-540
To elucidate further our SARs' study on the chemistry and cytotoxic activity and probe the structural requirement for the potent antitumor activity of beta-carbolines, a series of novel 1,9-disubstituted and 1,3,9-trisubstituted beta-carboline deriva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd1e3f735d97b6d926f87fd875b3efa
https://doi.org/10.1016/j.ejmech.2008.03.030
https://doi.org/10.1016/j.ejmech.2008.03.030