Výsledky vyhledávání

Metabonomics Indicates Inhibition of Fatty Acid Synthesis, β-Oxidation, and Tricarboxylic Acid Cycle in Triclocarban-Induced Cardiac Metabolic Alterations in Male Mice

Autor: Wenping Xie, Xiaomei Zhuang, Wenlian Yu, Yuan Cui, Wentao Li, Zhenqing Zhang, Wenpeng Zhang, Huiming Chen, Haishan Li, Guolin Shen, Juan Ren, Lili Zhou

Publikováno v: Journal of Agricultural and Food Chemistry. 66:1533-1542

Triclocarban (TCC) has been identified as a new environmental pollutant that is potentially hazardous to human health; however, the effects of short-term TCC exposure on cardiac function are not known. The aim of this study was to use metabonomics an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a77dc9e6b1d9ff1ad51bcbc77a321ee
https://doi.org/10.1021/acs.jafc.7b05220

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Evaluation of the migration of UV-ink photoinitiators from polyethylene food packaging by supercritical fluid chromatography combined with photodiode array detector and tandem mass spectrometry

Autor: Qiaozhen Guo, Zhenxia Du, Huijie Wu, Xueming Xia, Wenlian Yu, Yun Zhang

Publikováno v: Polymer Testing. 53:276-282

UV-ink photoinitiators (PIs), which are used to initiate polymerization reaction for the curing of inks and lacquers, have become a kind of contaminant residues in printing plastic food packaging. The residual PIs in packaging may pose a potential th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd09d0529a1a89c802c05f1eef716463
https://doi.org/10.1016/j.polymertesting.2016.06.008

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Detection and Identification of Leachables in Vaccine from Plastic Packaging Materials Using UPLC-QTOF MS with Self-Built Polymer Additives Library

Autor: Shuqi Sun, Zhenxia Du, Qiaozhen Guo, Yun Zhang, Wenlian Yu, Xuebin Xing

Publikováno v: Analytical Chemistry. 88:6749-6757

The direct contact of plastic parts with the medical products raises the possibility that plastic-related contaminants (leachables) may be present in the finished medical product. The leachable components from plastic materials may impact the safety

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457511548336b23d5bf62923d3d4dffa
https://doi.org/10.1021/acs.analchem.6b01027

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CYP450 Enzyme-Mediated Metabolism of TCAS and Its Inhibitory and Induced Effects on Metabolized Enzymes in Vitro

Autor: Huiming Chen, Wenlian Yu, Lei Li, Lili Zhou, Guolin Shen, Haishan Li, Cheng Wang

Publikováno v: International Journal of Environmental Research and Public Health
Volume 12
Issue 9
Pages 10783-10793
International Journal of Environmental Research and Public Health, Vol 12, Iss 9, Pp 10783-10793 (2015)

In this study, we investigated the enzymes catalyzing the phase I metabolism of thiacalixarene (TCAS) based on in vitro system including cDNA-expressed P450 enzymes, human liver microsomes plus inhibitors and monoclonal antibodies. In addition, the i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b46dd175637f7f6ff150f5044c6ebf6
https://doi.org/10.3390/ijerph120910783

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Development of a rapid detection method for eight organophosphate esters in plastic samples from automobile interiors using ultra-performance liquid chromatography tandem mass spectrometry with microwave assisted extraction

Autor: Yun Zhang, Wenlian Yu, Yiping Wang, Lili Zhou, Zhenxia Du

Publikováno v: Analytical Methods. 7:9861-9866

A rapid, effective and eco-friendly method for determination of eight organophosphate esters in plastic samples from car interiors by microwave assisted extraction followed by ultra-high performance liquid chromatography combined with tandem mass spe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::18df26f4d0659e41735d1e8a54124277
https://doi.org/10.1039/c5ay02077h

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Toxicity assessment of the extractables from multi-layer coextrusion poly ethylene bags exposed to pH=5 solution containing 4% benzyl alcohol and 0.1 M sodium acetate

Autor: Yan Dong, Sajid Hussain Siyal, Jingcong Zhuang, Zhenxia Du, Xuebin Xing, Di Wang, Wenlian Yu, Jianfeng Wang

Publikováno v: Regulatory toxicology and pharmacology : RTP. 94

A non-target analysis was developed for the analysis of extractables from multi-layer coextrusion bags exposed to 4% benzyl alcohol solution and 0.1 M sodium acetate at pH = 5 for defined periods (15 day, 45 day and 90 day) according to manufacturer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60fe8b35d27ee72a947997fb0fdb9b29
https://pubmed.ncbi.nlm.nih.gov/29360483

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Development of a plug-type IMS-MS instrument and its applications in resolving problems existing in in-situ detection of illicit drugs and explosives by IMS

Autor: Jianan Zhao, Zhongxia Zhang, Di Wang, Zhenxia Du, Wenlian Yu, Tangqiang Sun

Publikováno v: Talanta. 184

Ion mobility spectrometry (IMS) which acts as a rapid analysis technique is widely used in the field detection of illicit drugs and explosives. Due to limited separation abilities of the pint-sized IMS challenges and problems still exist regarding hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e11ef602f115644608ea83c79b9d67
https://pubmed.ncbi.nlm.nih.gov/29674084

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Di(2-ethylhexyl)phthalate Alters the Synthesis and β-Oxidation of Fatty Acids and Hinders ATP Supply in Mouse Testes via UPLC-Q-Exactive Orbitrap MS-Based Metabonomics Study

Autor: Wenlian Yu, Wenping Xie, Wei Liu, Haishan Li, Yuan Cui, Huiming Chen, Lili Zhou, Guolin Shen, Wentao Li

Publikováno v: Journal of agricultural and food chemistry. 65(24)

Di(2-ethylhexyl) phthalate (DEHP) is considered to be an environmental endocrine disruptor at high levels of general exposure. Studies show that DEHP may cause testicular toxicity on human being. In this study, metabonomics techniques were used to id

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b113d72ba6b4e84415863a3ce3ee8ef
https://pubmed.ncbi.nlm.nih.gov/28609104

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Tributyl phosphate impairs the urea cycle and alters liver pathology and metabolism in mice after short-term exposure based on a metabonomics study

Autor: Wenping Xie, Wenpeng Zhang, Haishan Li, Huiming Chen, Lili Zhou, Wenlian Yu, Guolin Shen

Publikováno v: The Science of the total environment.

As a newly emerging environmental contaminant, tributyl phosphate (TBP) is of increasing concern because of the environmental problems it can cause. Studies have suggested that TBP induces hepatocellular adenomas and has malignant potential for hepat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4970547df36d8184695735bc82dc8eda
https://pubmed.ncbi.nlm.nih.gov/28623793

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Simultaneous determination of bisphenol A, tetrabromobisphenol A, and perfluorooctanoic acid in small household electronics appliances of 'Prohibition on Certain Hazardous Substances in Consumer Products' instruction using ultra-performance liquid chromat

Autor: Wenlian Yu, Xiaoyu Lu, Zhenxia Du, Jinhua Wang, Qiaozhen Guo, Yun Zhang

Publikováno v: Journal of Separation Science. 36:677-683

Simultaneous determination of bisphenol A, tetrabromobisphenol A, and perfluorooctanoic acid in small household electronics appliances by accelerated solvent extraction-ultra-performance liquid chromatography-tandem mass spectrometry was established.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b972e0d06fa20316db7842d7fa265f96
https://doi.org/10.1002/jssc.201200730

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