Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Wenli, Fang"'
Autor:
Wenli Fang, Liyan Li, Zhongda Lin, Yuli Zhang, Zhangyan Jing, Yuan Li, Zhirang Zhang, Linlin Hou, Xin Liang, Xingding Zhang, Xudong Zhang
Publikováno v:
Extracellular Vesicle, Vol 2, Iss , Pp 100021- (2023)
Interleukin 15 (IL-15) is a pivotal immune cytokine that responses to cancer stress signals and maintains tissue-resident memory T (TRM) cells. It is therefore considered as a potent therapeutic immunomodulator agonist cancer. However, in addition to
Externí odkaz:
https://doaj.org/article/a7346331fdc34843ba16d5b08590b4a2
Autor:
Yuting Ruan, Ying Xiong, Wenli Fang, Qun Yu, Yingren Mai, Zhiyu Cao, Kexi Wang, Ming Lei, Jiaxin Xu, Yan Liu, Xingcai Zhang, Wang Liao, Jun Liu
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-21 (2022)
Abstract Background Alzheimer's disease (AD) is the most common neurodegenerative disorder without effective therapy and lack diagnosis strategy for preclinical AD patients. There is an urgent need for development of both early diagnosis and therapeu
Externí odkaz:
https://doaj.org/article/6c30e63b300b4b2a971511e6f8cb7776
Autor:
Husun Qian, Ting Zhou, Yixin Fu, Minkang Guo, Wu Yang, Dian Zhang, Wenli Fang, Mengli Yao, He Shi, Chengsen Chai, Wei Cheng, Shijia Ding, Tingmei Chen
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 763-773 (2022)
There is increasing interest in depleting or repolarizing tumor-associated macrophages (TAMs) to generate a proinflammatory effect. However, TAMs usually display an immunosuppressive M2-like phenotype in the tumor microenvironment. Apparently, develo
Externí odkaz:
https://doaj.org/article/1064384c6c2a43e7b42fd44335118f83
Autor:
Wenli Fang, Ting Zhou, He Shi, Mengli Yao, Dian Zhang, Husun Qian, Qian Zeng, Yange Wang, Fangfang Jin, Chengsen Chai, Tingmei Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-11 (2021)
Abstract Background Progranulin (PGRN), as a multifunctional growth factor, is overexpressed in multiple tumors, but the role of PGRN on tumor immunity is still unclear. Here, we studied the effect of PGRN on breast cancer tumor immunity and its poss
Externí odkaz:
https://doaj.org/article/1f3b7095807644b78563ed3fafea797a
Autor:
Qun Yu, Yingren Mai, Yuting Ruan, Yishan Luo, Lei Zhao, Wenli Fang, Zhiyu Cao, Yi Li, Wang Liao, Songhua Xiao, Vincent C. T. Mok, Lin Shi, Jun Liu, the National Alzheimer’s Coordinating Center, the Alzheimer’s Disease Neuroimaging Initiative, the Frontotemporal Lobar Degeneration Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2021)
Abstract Background The differential diagnosis of frontotemporal dementia (FTD) and Alzheimer’s disease (AD) is difficult due to the overlaps of clinical symptoms. Structural magnetic resonance imaging (sMRI) presents distinct brain atrophy and pot
Externí odkaz:
https://doaj.org/article/2e085d3e34f44ad592482df6ecc36800
Autor:
Zhiyu Cao, Yingren Mai, Wenli Fang, Ming Lei, Yishan Luo, Lei Zhao, Wang Liao, Qun Yu, Jiaxin Xu, Yuting Ruan, Songhua Xiao, Vincent C. T. Mok, Lin Shi, Jun Liu, The Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Frontiers in Human Neuroscience, Vol 16 (2022)
BackgroundWhite matter hyperintensities (WMHs) and regional brain lobe atrophy coexist in the brain of patients with Alzheimer's disease (AD), but the association between them in patients with AD still lacks comprehensive investigation and solid imag
Externí odkaz:
https://doaj.org/article/c1445bd80bc14ce1aa7069d8ca3f45ef
Autor:
Yingren Mai, Zhiyu Cao, Jiaxin Xu, Qun Yu, Shaoqing Yang, Jingyi Tang, Lei Zhao, Wenli Fang, Yishan Luo, Ming Lei, Vincent C. T. Mok, Lin Shi, Wang Liao, Jun Liu, the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Background and ObjectiveEarly identification is important for timely Alzheimer’s disease (AD) treatment. Apolipoprotein E ε4 allele (APOE-ε4) is an important genetic risk factor for sporadic AD. The AD-Resemblance Atrophy Index (RAI)—a structur
Externí odkaz:
https://doaj.org/article/bc3f1dbae7884e01bb6f8339dac806ee
Autor:
Wenli Fang, Ting Zhou, He Shi, Mengli Yao, Dian Zhang, Husun Qian, Qian Zeng, Yange Wang, Fangfang Jin, Chengsen Chai, Tingmei Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/d0d1e4ce50424d3184a9c674891eca1f
Autor:
Yuqiu Zheng, Wenli Fang, Shengnuo Fan, Wang Liao, Ying Xiong, Shaowei Liao, Yi Li, Songhua Xiao, Jun Liu
Publikováno v:
Journal of Pharmacological Sciences, Vol 136, Iss 4, Pp 242-248 (2018)
Neurotropin (NTP) is a widely used drug in China and Japan mainly for the treatment of chronic pain and peripheral inflammation. Nevertheless, the effects of NTP on neuroinflammation have not been explored. In this study, we investigated the anti-inf
Externí odkaz:
https://doaj.org/article/a368fecca51b4c3d8be5204d7b4fd8ff
Autor:
Shengnuo Fan, Yuqiu Zheng, Xuan Liu, Wenli Fang, Xiaoyu Chen, Wang Liao, Xiuna Jing, Ming Lei, Enxiang Tao, Qiulan Ma, Xingmei Zhang, Rui Guo, Jun Liu
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1091-1102 (2018)
Alzheimer’s disease is a neurodegenerative disorder mainly characterized by β-amyloid deposit and tau hyperphosphorylation with no curative treatments. Curcumin (Cur) has been proved to have potential use in Alzheimer’s disease with its anti-amy
Externí odkaz:
https://doaj.org/article/5a8568acd3c64032a59acc4889930994