Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Wenlei Ye"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Secondary ovarian tumor [secondary tumor of the ovary (STO)] is not a frequent disease. To date, there is still a lack of standard treatment for STO due to the relative heterogeneity. Liver cancer metastasis to the ovary is extremely rare, with only
Externí odkaz:
https://doaj.org/article/6eb7e00929894fa69a70f7dc82e7348a
Autor:
Mu He, Bing Wu, Wenlei Ye, Daniel D Le, Adriane W Sinclair, Valeria Padovano, Yuzhang Chen, Ke-Xin Li, Rene Sit, Michelle Tan, Michael J Caplan, Norma Neff, Yuh Nung Jan, Spyros Darmanis, Lily Yeh Jan
Publikováno v:
eLife, Vol 9 (2020)
The conducting airway forms a protective mucosal barrier and is the primary target of airway disorders. The molecular events required for the formation and function of the airway mucosal barrier, as well as the mechanisms by which barrier dysfunction
Externí odkaz:
https://doaj.org/article/3a06ea545a1440859b05a65eab370713
Autor:
Ke-Xin Li, Mu He, Wenlei Ye, Jeffrey Simms, Michael Gill, Xuaner Xiang, Yuh Nung Jan, Lily Yeh Jan
Publikováno v:
eLife, Vol 8 (2019)
TMEM16B (ANO2) is the Ca2+-activated chloride channel expressed in multiple brain regions, including the amygdala. Here we report that Ano2 knockout mice exhibit impaired anxiety-related behaviors and context-independent fear memory, thus implicating
Externí odkaz:
https://doaj.org/article/d3acbc4e646f4d7a8b43350142ba315c
Autor:
Shengjie Feng, Shangyu Dang, Tina Wei Han, Wenlei Ye, Peng Jin, Tong Cheng, Junrui Li, Yuh Nung Jan, Lily Yeh Jan, Yifan Cheng
Publikováno v:
Cell Reports, Vol 28, Iss 2, Pp 567-579.e4 (2019)
Summary: As a Ca2+-activated lipid scramblase and ion channel that mediates Ca2+ influx, TMEM16F relies on both functions to facilitate extracellular vesicle generation, blood coagulation, and bone formation. How a bona fide ion channel scrambles lip
Externí odkaz:
https://doaj.org/article/6686448e492142678c042251216769d5
Publikováno v:
eLife, Vol 8 (2019)
TMEM16F is activated by elevated intracellular Ca2+, and functions as a small-conductance ion channel and as a phospholipid scramblase. In contrast to its paralogs, the TMEM16A/B calcium-activated chloride channels, mouse TMEM16F has been reported as
Externí odkaz:
https://doaj.org/article/46e398b2d1634407bc15e1cffcb0e2be
Autor:
Meng, Wu, Zhiyong, Lu, Qingqing, Zhu, Lingwei, Ma, Liru, Xue, Yan, Li, Su, Zhou, Wei, Yan, Wenlei, Ye, Jinjin, Zhang, Aiyue, Luo, Shixuan, Wang
Publikováno v:
Stem Cells. 40:88-101
Ovarian aging is a pacemaker with multiple organ dysfunction. Recently, stem cells with the ability to generate new oocytes have been identified, which provides the possibility of stem cell therapy for ovarian aging. Several studies have revealed the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6dfa66236388ea1db5b22acf669b80
https://doi.org/10.1093/stmcls/sxab002
https://doi.org/10.1093/stmcls/sxab002
Autor:
Samuel T. Slocum, Yongfeng Liu, Bryan L. Roth, Jian Jin, Brian E. Krumm, Brian J. Bender, Reid H.J. Olsen, Hye Jin Kang, Justin G. English, Isha Singh, Jing Liu, Lily Yeh Jan, Wenlei Ye, Brian K. Shoichet, Xi Ping Huang, Byron W. Hayes, Can Cao, John D. McCorvy, Jonathan F. Fay, Katherine Lansu, Soman N. Abraham, Shicheng Zhang, Chengwei Zhang, Wesley K. Kroeze, Kuglae Kim, He Chen, Ryan H. Gumpper, Jeffrey F. DiBerto, Joel Karpiak
Publikováno v:
Nature
Nature, vol 600, iss 7887
Nature, vol 600, iss 7887
The MRGPRX family of receptors (MRGPRX1–4) is a family of mas-related G-protein-coupled receptors that have evolved relatively recently1. Of these, MRGPRX2 and MRGPRX4 are key physiological and pathological mediators of itch and related mast cell-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e74bb609d8bd744fc782cf9ab54a3d
https://doi.org/10.1038/s41586-021-04126-6
https://doi.org/10.1038/s41586-021-04126-6
Activation and closed-state inactivation mechanisms of the human voltage-gated KV4 channel complexes
Publikováno v:
Molecular cell, vol 82, iss 13
The voltage-gated ion channel activity depends on both activation (transition from the resting state to the open state) and inactivation. Inactivation is a self-restraint mechanism to limit ion conduction and is as crucial to membrane excitability as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0fe105c07ee874ae8842dff939cd79
https://escholarship.org/uc/item/0tj7f6hp
https://escholarship.org/uc/item/0tj7f6hp
Autor:
Wenlei, Ye, Hongtu, Zhao, Yaxin, Dai, Yingdi, Wang, Yu-Hua, Lo, Lily Yeh, Jan, Chia-Hsueh, Lee
Publikováno v:
Mol Cell
The voltage-gated ion channel activity depends on both activation (transition from the resting state to the open state) and inactivation. Inactivation is a self-restraint mechanism to limit ion conduction and is as crucial to membrane excitability as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eabd3dad2d5ab261c68481ebad148301
https://pubmed.ncbi.nlm.nih.gov/35597238
https://pubmed.ncbi.nlm.nih.gov/35597238
Autor:
Jinjin Zhang, Meng Wu, Liru Xue, Lingwei Ma, Dan Chen, Shixuan Wang, Aiyue Luo, Xiang Li, Zixin Hong, Yan Jin, Xian Qin, Weicheng Tang, Zhiyong Lu, Wenlei Ye, Yingying Chen
Publikováno v:
Aging (Albany NY)
Chemotherapy-induced ovarian aging not only increases the risk for early menopause-related complications but also results in infertility in young female cancer survivors. Oogonial stem cells have the ability to generate new oocytes and thus provide n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2c528230a8d6c9c7d68a2caa2d3510
https://doi.org/10.18632/aging.102852
https://doi.org/10.18632/aging.102852