Zobrazeno 1 - 10 of 74 pro vyhledávání: '"Wenle Zhao"'
1
Akademický článek
Selecting a randomization method for a multi-center clinical trial with stochastic recruitment considerations
Autor: Oleksandr Sverdlov, Yevgen Ryeznik, Volodymyr Anisimov, Olga M. Kuznetsova, Ruth Knight, Kerstine Carter, Sonja Drescher, Wenle Zhao
Publikováno v: BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-23 (2024)
Abstract Background The design of a multi-center randomized controlled trial (RCT) involves multiple considerations, such as the choice of the sample size, the number of centers and their geographic location, the strategy for recruitment of study par
Externí odkaz: https://doaj.org/article/69347b89448b4b2a859933c3f412fa5c
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2
Akademický článek
Preventing Ischemic Cerebrovascular Events in High-Risk Patients With Non-disabling Ischemic Cerebrovascular Events Using Remote Ischemic Conditioning: A Single-Arm Study
Autor: Shimeng Liu, Zongen Gao, Ran Meng, Haiqing Song, Tianping Tang, Ya Zhao, Rong Chen, Yanzhen Sheng, Qianqian Fan, Fang Jiang, Qian Zhang, Jianping Ding, Xiaoqin Huang, Qingfeng Ma, Kai Dong, Sufang Xue, Zhipeng Yu, Jiangang Duan, Changbiao Chu, Xiaohui Chen, Xingquan Huang, Sijie Li, Bruce Ovbiagele, Wenle Zhao, Xunming Ji, Wuwei Feng
Publikováno v: Frontiers in Neurology, Vol 12 (2021)
Background: Secondary stroke prevention after a high-risk, non-disabling ischemic cerebrovascular event needs to be enhanced. The study was conducted to investigate whether remote ischemic conditioning (RIC) is effective in preventing recurrent ische
Externí odkaz: https://doaj.org/article/ddf434aa69144823a0159faa77b88d73
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3
Akademický článek
Generalization of Wei's urn design to unequal allocations in sequential clinical trials
Autor: Wenle Zhao, Viswanathan Ramakrishnan
Publikováno v: Contemporary Clinical Trials Communications, Vol 2, Iss C, Pp 75-79 (2016)
Wei's urn design was proposed in 1987 for subject randomization in trials comparing m≥2 treatments with equal allocation. In this manuscript, two modified versions of Wei's urn design are presented to accommodate unequal allocations. First one uses
Externí odkaz: https://doaj.org/article/d0140b4b14894614b325ac5c01a395e2
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5
Impact of minimal sufficient balance, minimization, and stratified permuted blocks on bias and power in the estimation of treatment effect in sequential clinical trials with a binary endpoint
Autor: Steven D. Lauzon, Jody D. Ciolino, Wenle Zhao, Michael D. Hill, Paul J. Nietert, Viswanathan Ramakrishnan
Publikováno v: Stat Methods Med Res
Minimization is among the most common methods for controlling baseline covariate imbalance at the randomization phase of clinical trials. Previous studies have found that minimization does not preserve allocation randomness as well as other methods,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba80f67752a95449347c6cb182c1a8f3
https://doi.org/10.1177/09622802211055856
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8
A novel microRNA-based prognostic model outperforms standard prognostic models in patients with acetaminophen-induced acute liver failure
Autor: Oliver D. Tavabie, Constantine J. Karvellas, Siamak Salehi, Jaime L. Speiser, Christopher F. Rose, Krishna Menon, Andreas Prachalias, Michael A. Heneghan, Kosh Agarwal, William M. Lee, Mark J.W. McPhail, Varuna R. Aluvihare, W.M. Lee, Anne M. Larson, Iris Liou, Oren Fix, Michael Schilsky, Timothy McCashland, J. Eileen Hay, Natalie Murray, A. Obaid S. Shaikh, Andres Blei, Daniel Ganger, Atif Zaman, Steven H.B. Han, Robert Fontana, Brendan McGuire, Raymond T. Chung, Alastair Smith, Robert Brown, Jeffrey Crippin, Edwin Harrison, Adrian Reuben, Santiago Munoz, Rajender Reddy, R. Todd Stravitz, Lorenzo Rossaro, Raj Satyanarayana, Tarek Hassanein, Jodi Olson, Ram Subramanian, James Hanje, Bilal Hameed, Ezmina Lalani, Carla Pezzia, Corron Sanders, Nahid Attar, Linda S. Hynan, Valerie Durkalski, Wenle Zhao, Jaime Speiser, Catherine Dillon, Holly Battenhouse, Michelle Gottfried
Publikováno v: Journal of hepatology. 75(2)
Background & Aims Acetaminophen (APAP)-induced acute liver failure (ALF) remains the most common cause of ALF in the Western world. Conventional prognostic models, utilising markers of liver injury and organ failure, lack sensitivity for mortality pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a43ba252019ddf9108b71a7986606fe
https://pubmed.ncbi.nlm.nih.gov/33857547
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10
Bayesian Response Adaptive Randomization in Clinical Trials With a Time-trend: Application to a Real Trial
Autor: Yunyun Jiang, Valerie Durkalski-Mauldin, Wenle Zhao
Background: In clinical trials with a large sample size, time-trend in response rates can affect the performance of Bayesian response adaptive randomization (BRAR).Methods: To evaluate this impact, we utilize data from a previously completed randomiz
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2533c0c4bf5fdd2bfd494f6d15da49dc
https://doi.org/10.21203/rs.3.rs-35671/v1
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