Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Wenkuan, Xin"'
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Previous studies showed that berberine, an alkaloid from Coptis Chinensis Franch, might exert a positive inotropic effect on the heart. However, the underlying mechanisms were unclear. Here, we reported that berberine at 10–20 µM increased the lef
Externí odkaz:
https://doaj.org/article/dc98198abce4419eb986f8c220655ab9
Hippocampal protein kinase D1 is necessary for DHPG-induced learning and memory impairments in rats.
Autor:
Wei Wang, Florian Duclot, Bradley R Groveman, Nicole Carrier, Haifa Qiao, Xiao-Qian Fang, Hui Wang, Wenkuan Xin, Xing-Hong Jiang, Michael W Salter, Xin-Sheng Ding, Mohamed Kabbaj, Xian-Min Yu
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195095 (2018)
BackgroundUnderstanding molecular mechanisms underlying the induction of learning and memory impairments remains a challenge. Recent investigations have shown that the activation of group I mGluRs (mGluR1 and mGluR5) in cultured hippocampal neurons b
Externí odkaz:
https://doaj.org/article/715f30ef33074c678a955ad5a7673164
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2483
In the last 20 years tremendous progress has been made in the development of single cell cAMP sensors. Sensors are based upon cAMP binding proteins that have been modified to transduce cAMP concentrations into electrical or fluorescent readouts that
Publikováno v:
cAMP Signaling ISBN: 9781071622445
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40ceed6a0a370b20a2bfd6474eb429af
https://doi.org/10.1007/978-1-0716-2245-2_17
https://doi.org/10.1007/978-1-0716-2245-2_17
Publikováno v:
The FASEB Journal. 35
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Previous studies showed that berberine, an alkaloid from Coptis Chinensis Franch, might exert a positive inotropic effect on the heart. However, the underlying mechanisms were unclear. Here, we reported that berberine at 10-20 µM increased the left
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 394(4)
Bile acids are endogenous amphiphilic steroids from the metabolites of cholesterol. Studies showed that they might contribute to the pathogenesis of cardiopathy in cholestatic liver diseases. Chenodeoxycholic acid (CDCA) and deoxycholic acid (DCA) is
Publikováno v:
European journal of pharmacology. 876
Bitter taste receptors (Tas2rs), the members of the G-protein-coupled receptors, mediate the bitter taste and express in extra-oral tissues. Previous studies have shown that Tas2r mRNAs are expressed in the whole heart and cultured cardiomyocytes of
Publikováno v:
Frontiers in Pharmacology
Previous studies showed that berberine, an alkaloid from Coptis Chinensis Franch, might exert a positive inotropic effect on the heart. However, the underlying mechanisms were unclear. Here, we reported that berberine at 10–20 µM increased the lef
Publikováno v:
American Journal of Physiology-Renal Physiology. 310:F994-F999
Large-conductance Ca2+-activated K+ (BK) channels are critical regulators of detrusor smooth muscle (DSM) function. We aimed to investigate phosphodiesterase type 1 (PDE1) interactions with BK channels in human DSM to determine the mechanism by which