Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Wenke Jin"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 2815-2853 (2024)
Regulated cell death (RCD) is a controlled form of cell death orchestrated by one or more cascading signaling pathways, making it amenable to pharmacological intervention. RCD subroutines can be categorized as apoptotic or non-apoptotic and play esse
Externí odkaz:
https://doaj.org/article/0881ed82ae084982ab8caa3190444a8b
Autor:
Fu Peng, Minru Liao, Wenke Jin, Wei Liu, Zixiang Li, Zhichao Fan, Ling Zou, Siwei Chen, Lingjuan Zhu, Qian Zhao, Gu Zhan, Liang Ouyang, Cheng Peng, Bo Han, Jin Zhang, Leilei Fu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Sirtuin 3 (SIRT3) is well known as a conserved nicotinamide adenine dinucleotide+ (NAD+)-dependent deacetylase located in the mitochondria that may regulate oxidative stress, catabolism and ATP production. Accumulating evidence has recently
Externí odkaz:
https://doaj.org/article/0c9da444ccf442e3b3e6e2e182b75a0c
Publikováno v:
Journal of Advanced Research, Vol 58, Iss , Pp 175-191 (2024)
Background: Autophagy refers to the conserved cellular catabolic process relevant to lysosome activity and plays a vital role in maintaining the dynamic equilibrium of intracellular matter by degrading harmful and abnormally accumulated cellular comp
Externí odkaz:
https://doaj.org/article/d82398263bac4cdfa96121953ed7acd8
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-6 (2022)
Abstract Hepatocellular carcinoma (HCC) is well-known to be a highly prevalent malignant tumor, but the treatment of this pathological state has been still challenging. Solamargine (SM), a traditional Chinese herb-derived compound, has been widely re
Externí odkaz:
https://doaj.org/article/bfb563af3ae84c938161ad0aa86438e4
Autor:
Leilei Fu, Wenke Jin, Jiahui Zhang, Lingjuan Zhu, Jia Lu, Yongqi Zhen, Lan Zhang, Liang Ouyang, Bo Liu, Haiyang Yu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 2, Pp 532-557 (2022)
Drug repurposing or repositioning has been well-known to refer to the therapeutic applications of a drug for another indication other than it was originally approved for. Repurposing non-oncology small-molecule drugs has been increasingly becoming an
Externí odkaz:
https://doaj.org/article/a0d1d39b63ae40929af3862c8cf6140c
Publikováno v:
Drug Discovery Today. 27:2373-2385
Autophagy, an evolutionarily highly conserved cellular degradation process, plays the Janus role (either cytoprotective or death-promoting) in colorectal cancer, so the targeting of several key autophagic pathways with small-molecule compounds may be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f70db47c3d6f54023f391215a98762f
https://doi.org/10.1016/j.drudis.2022.05.011
https://doi.org/10.1016/j.drudis.2022.05.011
Publikováno v:
Journal of Advanced Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::104e8721edae7c815f0e56bee79581c6
https://doi.org/10.1016/j.jare.2023.05.002
https://doi.org/10.1016/j.jare.2023.05.002
Autor:
Bo Liu, Jia Lu, Haiyang Yu, Wenke Jin, Liang Ouyang, Yongqi Zhen, Lan Zhang, Leilei Fu, Jiahui Zhang, Lingjuan Zhu
Publikováno v:
Acta Pharmaceutica Sinica B. 12:532-557
Drug repurposing or repositioning has been well-known to refer to the therapeutic applications of a drug for another indication other than it was originally approved for. Repurposing non-oncology small-molecule drugs has been increasingly becoming an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc524d5a225039d9ef58e98400671c5
https://doi.org/10.1016/j.apsb.2021.09.006
https://doi.org/10.1016/j.apsb.2021.09.006
Publikováno v:
Drug Discovery Today. 27:612-625
Evasion of regulated cell death (RCD), mainly referring to apoptosis, autophagy-dependent cell death, necroptosis, and other subroutines, is one of the well-established hallmarks of cancer cells. Accumulating evidence has revealed several small-molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01dd6d74be2552ae0a8249498ea15fb2
https://doi.org/10.1016/j.drudis.2021.10.011
https://doi.org/10.1016/j.drudis.2021.10.011
Publikováno v:
Pharmacogenetics and Genomics. 32:125-137
Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumors worldwide and there are few crucial regulators and druggable targets for early diagnosis. Therefore, the identification of biomarkers for the early diagnosis and druggable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cbecf063833c3bd85a7ba477f36d41
https://doi.org/10.1097/fpc.0000000000000461
https://doi.org/10.1097/fpc.0000000000000461