Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Wenkan, Zhang"'
Autor:
Yikan Sun, Eloy Yinwang, Shengdong Wang, Zenan Wang, Fangqian Wang, Yucheng Xue, Wenkan Zhang, Shenzhi Zhao, Haochen Mou, Shixin Chen, Lingxiao Jin, Binghao Li, Zhaoming Ye
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract CD8+ T cells are the workhorses executing adaptive anti-tumour response, and targets of various cancer immunotherapies. Latest advances have unearthed the sheer heterogeneity of CD8+ tumour infiltrating lymphocytes, and made it increasingly
Externí odkaz:
https://doaj.org/article/fdda9f8f7434471a9afa3fccca6f7920
Autor:
Tao Chen, Hao Zhou, Shuming Li, Nong Lin, Yixuan Feng, Zhijian Cai, Chenxiao Qiao, Eloy Yinwang, Shengdong Wang, Xuehuan Wen, Xiangang Jin, Yucheng Xue, Wenkan Zhang, Xianchang Zeng, Zenan Wang, Hangxiang Sun, Lifeng Jiang, Hengyuan Li, Binghao Li, Zhaoming Ye
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 12 (2024)
Background Lung metastasis remains the primary cause of tumor-related mortality, with limited treatment options and unsatisfactory efficacy. In preclinical studies, T helper 9 (TH9) cells have shown promise in treating solid tumors. However, it is un
Externí odkaz:
https://doaj.org/article/b92421f8a0604580b6a9ff63fc5af99b
Autor:
Peng Liao, Long Chen, Hao Zhou, Jiong Mei, Ziming Chen, Bingqi Wang, Jerry Q. Feng, Guangyi Li, Sihan Tong, Jian Zhou, Siyuan Zhu, Yu Qian, Yao Zong, Weiguo Zou, Hao Li, Wenkan Zhang, Meng Yao, Yiyang Ma, Peng Ding, Yidan Pang, Chuan Gao, Jialun Mei, Senyao Zhang, Changqing Zhang, Delin Liu, Minghao Zheng, Junjie Gao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Transcortical vessels (TCVs) provide effective communication between bone marrow vascular system and external circulation. Although osteocytes are in close contact with them, it is not clear whether osteocytes regulate the homeostasis of TCV
Externí odkaz:
https://doaj.org/article/ad943aec28154a83935fa353a33c907a
Autor:
Shixin Chen, Jiangchu Lei, Haochen Mou, Wenkan Zhang, Lingxiao Jin, Senxu Lu, Eloy Yinwang, Yucheng Xue, Zhenxuan Shao, Tao Chen, Fangqian Wang, Shenzhi Zhao, Xupeng Chai, Zenan Wang, Jiahao Zhang, Zengjie Zhang, Zhaoming Ye, Binghao Li
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Bone is a common organ for solid tumor metastasis. Malignant bone tumor becomes insensitive to systemic therapy after colonization, followed by poor prognosis and high relapse rate. Immune and bone cells in situ constitute a unique immune microenviro
Externí odkaz:
https://doaj.org/article/d2f9affd5a4544f18bff4aeeb0e3ca54
Autor:
Tao Chen, Yucheng Xue, Shengdong Wang, Jinwei Lu, Hao Zhou, Wenkan Zhang, Zhiyi Zhou, Binghao Li, Yong Li, Zenan Wang, Changwei Li, Yinwang Eloy, Hangxiang Sun, Yihang Shen, Mohamed Diaty Diarra, Chang Ge, Xupeng Chai, Haochen Mou, Peng Lin, Xiaohua Yu, Zhaoming Ye
Publikováno v:
Bioactive Materials, Vol 23, Iss , Pp 508-523 (2023)
Insufficient infiltration of T cells severely compromises the antitumor efficacy of adoptive cell therapy (ACT) against solid tumors. Here, we present a facile immune cell surface engineering strategy aiming to substantially enhance the anti-tumor ef
Externí odkaz:
https://doaj.org/article/5f5e8f8ff6a1474f944c8a3e823b0570
Autor:
Wenkan Zhang, Hao Zhou, Hengyuan Li, Haochen Mou, Eloy Yinwang, Yucheng Xue, Shengdong Wang, Yongxing Zhang, Zenan Wang, Tao Chen, Hangxiang Sun, Fangqian Wang, Jiahao Zhang, Xupeng Chai, Shixin Chen, Binghao Li, Changqing Zhang, Junjie Gao, Zhaoming Ye
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113464- (2023)
Externí odkaz:
https://doaj.org/article/c1c04bfd7d6c43fb802cf31a6b79191e
Autor:
Zenan Wang, Binghao Li, Shan Li, Wenlong Lin, Zhan Wang, Shengdong Wang, Weida Chen, Wei Shi, Tao Chen, Hao Zhou, Eloy Yinwang, Wenkan Zhang, Haochen Mou, Xupeng Chai, Jiahao Zhang, Zhimin Lu, Zhaoming Ye
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Chemo-resistance and immune evasion are major challenges in osteosarcoma treatment. Here the authors show that doxorubicin promotes IL-18 secretion by tumor associated macrophages inducing LAT2-dependent CD47 upregulation in osteosarcoma cells, sugge
Externí odkaz:
https://doaj.org/article/242307c6508642058c15bbbd18691354
Publikováno v:
Chinese Medicine, Vol 17, Iss 1, Pp 1-13 (2022)
Abstract Background Excessive osteoclast activation is an important cause of imbalanced bone remodeling that leads to pathological bone destruction. This is a clear feature of many osteolytic diseases such as rheumatoid arthritis, osteoporosis, and o
Externí odkaz:
https://doaj.org/article/f4965201b3e94558a67f5c9b96c58740
Publikováno v:
Chinese Medicine, Vol 16, Iss 1, Pp 1-21 (2021)
Abstract Background Osteosarcoma is a malignant tumor of bone and soft tissue in adolescents. Due to its tumor biological behavior pattern, osteosarcoma usually generates poor prognosis. Autophagy is an important self-defense mechanism in osteosarcom
Externí odkaz:
https://doaj.org/article/63bf3f15da5c4a68938498d768b4fa9d
Autor:
Xupeng Chai, Eloy Yinwang, Zenan Wang, Zhan Wang, Yucheng Xue, Binghao Li, Hao Zhou, Wenkan Zhang, Shengdong Wang, Yongxing Zhang, Hengyuan Li, Haochen Mou, Lingling Sun, Hao Qu, Fangqian Wang, Zengjie Zhang, Tao Chen, Zhaoming Ye
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Lung cancer is the leading cause of cancer-related death worldwide. Bone metastasis, which usually accompanies severe skeletal-related events, is the most common site for tumor distant dissemination and detected in more than one-third of patients wit
Externí odkaz:
https://doaj.org/article/03f0ca39ada54e26a4a46b4088495c4f