Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Wenjun Guan"'
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 10, Pp n/a-n/a (2024)
Abstract Streptomyces genus produces a large number of antibiotics, which are always synthesized by specific biosynthetic gene clusters (BGCs). To resist autotoxicity, transporters encoded by genes located within BGC occasionally pump antibiotic alon
Externí odkaz:
https://doaj.org/article/069cf252a9934b0a807cdd55dd5a1f01
Autor:
Quanchao Zhu, Zuyuan Jia, Yuchao Song, Weiwang Dou, Daniel Henry Scharf, Xiaodan Wu, Zhihao Xu, Wenjun Guan
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT In order to produce therapeutic glycoproteins modified with human-like N-glycan structures, much progress has been achieved toward the humanization of N-glycosylation pathways in yeasts. In this study, a Pichia pastoris mutant Glyco4, which
Externí odkaz:
https://doaj.org/article/fc638752436141c7a673146bf34994f0
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 12, Pp 2890-2904 (2022)
Abstract Streptomyces is well known for synthesis of many biologically active secondary metabolites, such as polyketides and non‐ribosomal peptides. Understanding the coupling mechanisms of primary and secondary metabolism can help develop strategi
Externí odkaz:
https://doaj.org/article/f0481ad06c37480a97037364e1cfbc9d
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-12 (2021)
Abstract Background Due to its ability to perform fast and high-density fermentation, Pichia pastoris is not only used as an excellent host for heterologous protein expression but also exhibits good potential for efficient biosynthesis of small-molec
Externí odkaz:
https://doaj.org/article/7d3324e159e644008221d7c0b881e30c
Publikováno v:
Biosensors, Vol 11, Iss 1, p 13 (2020)
High levels of blood glucose are always associated with numerous complications including cholesterol abnormalities. Therefore, it is important to simultaneously monitor blood glucose and cholesterol levels in patients with diabetes during the managem
Externí odkaz:
https://doaj.org/article/8850e1ceb09a4ec69ed09873f23eadc6
Publikováno v:
Sensors, Vol 8, Iss 3, Pp 1712-1718 (2008)
A novel needle-type biosensor based on carbon nanotubes is reported. Thebiosensor was prepared by packing a mixture of multi-wall carbon nanotubes (MWCNTs),graphite powder and glucose oxidase (Gox) freeze-dried powder into a glass capillary of 0.5mm
Externí odkaz:
https://doaj.org/article/44856d3dd3e14940aec582f6303d77c2
Autor:
Xiaoxian Guo, Jingkai Li, Tanjun Wang, Zhenhua Liu, Xin Chen, Yudong Li, Zhenglong Gu, Xuming Mao, Wenjun Guan, Yongquan Li
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29520 (2012)
Multidrug resistance protein Pdr5p is a yeast ATP-binding cassette (ABC) transporter in the plasma membrane. It confers multidrug resistance by active efflux of intracellular drugs. However, the highly polymorphic Pdr5p from clinical strain YJM789 lo
Externí odkaz:
https://doaj.org/article/6438c171d6654021b74b6c19179b3d6a
Publikováno v:
PLoS Genetics, Vol 6, Iss 7, p e1001030 (2010)
Genome-wide studies of post-transcriptional mRNA regulation in model organisms indicate a "post-transcriptional RNA regulon" model, in which a set of functionally related genes is regulated by mRNA-binding RNAs or proteins. One well-studied post-tran
Externí odkaz:
https://doaj.org/article/9ccd8b0caf634f728a166293dbbc895a
Autor:
Wenjun Guan, Huifeng Jiang, Xiaoxian Guo, Eugenio Mancera, Lin Xu, Yudong Li, Lars Steinmetz, Yongquan Li, Zhenglong Gu
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11309 (2010)
Fungal pathogens can be lethal, especially among immunocompromised populations, such as patients with AIDS and recipients of tissue transplantation or chemotherapy. Prolonged usage of antifungal reagents can lead to drug resistance and treatment fail
Externí odkaz:
https://doaj.org/article/364991c3e64046fe93c5bb6078390fc7
Publikováno v:
Microbial Biotechnology. 15:2890-2904
Streptomyces is well known for synthesis of many biologically active secondary metabolites, such as polyketides and non-ribosomal peptides. Understanding the coupling mechanisms of primary and secondary metabolism can help develop strategies to impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659b2a7ba5dd860d49452ea9ac1c45d8
https://doi.org/10.1111/1751-7915.14145
https://doi.org/10.1111/1751-7915.14145