Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Wenjie Shu"'
Autor:
Xiaolong Qi, Lei Tan, Xu Zhang, Jiachuan Jin, Weining Kong, Wei Chen, Jianying Wang, Wei Dong, Lijuan Gao, Lijun Luo, Dan Lu, Jianan Gong, Feifei Guan, Wenjie Shu, Xingxu Huang, Lianfeng Zhang, Shengqi Wang, Bin Shen, Yuanwu Ma
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 1-12 (2023)
An animal model harboring pathogenic mitochondrial DNA (mtDNA) mutations is important to understand the biological links between mtDNA variation and mitochondrial diseases. DdCBE, a DddA-derived cytosine base editor, has been utilized in zebrafish, m
Externí odkaz:
https://doaj.org/article/5fec15f903074ea0bb43ff47c0829dd7
Autor:
Liangchen Yue, Feng Liu, Jiongsong Hu, Pin Yang, Yuxiang Wang, Junguo Dong, Wenjie Shu, Xingxu Huang, Shengqi Wang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 940-955 (2023)
Advances in transcriptomic technologies have deepened our understanding of the cellular gene expression programs of multicellular organisms and provided a theoretical basis for disease diagnosis and therapy. However, both bulk and single-cell RNA seq
Externí odkaz:
https://doaj.org/article/b2ffdea997f54a478e6a731919f4c5bb
Autor:
Jiao Fan, Yige Ding, Chao Ren, Ziguo Song, Jie Yuan, Qiuzhen Chen, Chenchen Du, Chao Li, Xiaolong Wang, Wenjie Shu
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Jiao Fan, Yige Ding, et al. examine the impact of cytosine and adenine deaminases on transcriptome-wide gene expression and splicing in HeLa and HEK293T cells. They found that both kinds of editors could induce broad changes in expression and splicin
Externí odkaz:
https://doaj.org/article/d7eb1dadf68045f89f9b6517005e2443
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/b15cc969cf6841e68372b838c11a7126
Autor:
Yunbo Qiao, Chao Ren, Shisheng Huang, Jie Yuan, Xingchen Liu, Jiao Fan, Jianxiang Lin, Susu Wu, Qiuzhen Chen, Xiaochen Bo, Xiangyang Li, Xingxu Huang, Zhen Liu, Wenjie Shu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Until now, the transcriptome of preimplantation mouse embryos has only been analysed by short-read sequencing. Here, the authors perform long-read sequencing to provide a more detailed transcriptome of the preimplantation mouse embryo, identifying va
Externí odkaz:
https://doaj.org/article/8037144ef5c94845a8eb375c83c2098a
Autor:
Chensi Cao, Feng Liu, Hai Tan, Deshou Song, Wenjie Shu, Weizhong Li, Yiming Zhou, Xiaochen Bo, Zhi Xie
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 16, Iss 1, Pp 17-32 (2018)
Advances in biological and medical technologies have been providing us explosive volumes of biological and physiological data, such as medical images, electroencephalography, genomic and protein sequences. Learning from these data facilitates the und
Externí odkaz:
https://doaj.org/article/f39538e8327345219d9feb75d33d2ddd
Autor:
Yunbo Qiao, Chao Ren, Shisheng Huang, Jie Yuan, Xingchen Liu, Jiao Fan, Jianxiang Lin, Susu Wu, Qiuzhen Chen, Xiaochen Bo, Xiangyang Li, Xingxu Huang, Zhen Liu, Wenjie Shu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-22148-6
Externí odkaz:
https://doaj.org/article/edec88eab53c443e831af5fbe98f1037
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168607 (2016)
Accurately identifying the binding sites of transcription factors (TFs) is crucial to understanding the mechanisms of transcriptional regulation and human disease. We present incorporating Find Occurrence of Regulatory Motifs (iFORM), an easy-to-use
Externí odkaz:
https://doaj.org/article/fdd332da954e4582936ae829575df9d1
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41374 (2012)
Chromatin insulators are DNA elements that regulate the level of gene expression either by preventing gene silencing through the maintenance of heterochromatin boundaries or by preventing gene activation by blocking interactions between enhancers and
Externí odkaz:
https://doaj.org/article/9f5567b2bb7c47e99da0cbaa93ec6426
Autor:
wenjie shu, 徐文杰
88
Conventional design of pile groups is based on the trial-and-error procedures. Although the design results can satisfy safety requirements, it is not a minimum cost design. The purpose of this study is to apply nonlinear programming methods f
Conventional design of pile groups is based on the trial-and-error procedures. Although the design results can satisfy safety requirements, it is not a minimum cost design. The purpose of this study is to apply nonlinear programming methods f
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/66458229943177767909