Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Wenjie Shu"'
Autor:
Xiaolong Qi, Lei Tan, Xu Zhang, Jiachuan Jin, Weining Kong, Wei Chen, Jianying Wang, Wei Dong, Lijuan Gao, Lijun Luo, Dan Lu, Jianan Gong, Feifei Guan, Wenjie Shu, Xingxu Huang, Lianfeng Zhang, Shengqi Wang, Bin Shen, Yuanwu Ma
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 1-12 (2023)
An animal model harboring pathogenic mitochondrial DNA (mtDNA) mutations is important to understand the biological links between mtDNA variation and mitochondrial diseases. DdCBE, a DddA-derived cytosine base editor, has been utilized in zebrafish, m
Externí odkaz:
https://doaj.org/article/5fec15f903074ea0bb43ff47c0829dd7
Autor:
Liangchen Yue, Feng Liu, Jiongsong Hu, Pin Yang, Yuxiang Wang, Junguo Dong, Wenjie Shu, Xingxu Huang, Shengqi Wang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 940-955 (2023)
Advances in transcriptomic technologies have deepened our understanding of the cellular gene expression programs of multicellular organisms and provided a theoretical basis for disease diagnosis and therapy. However, both bulk and single-cell RNA seq
Externí odkaz:
https://doaj.org/article/b2ffdea997f54a478e6a731919f4c5bb
Autor:
Jiao Fan, Yige Ding, Chao Ren, Ziguo Song, Jie Yuan, Qiuzhen Chen, Chenchen Du, Chao Li, Xiaolong Wang, Wenjie Shu
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Jiao Fan, Yige Ding, et al. examine the impact of cytosine and adenine deaminases on transcriptome-wide gene expression and splicing in HeLa and HEK293T cells. They found that both kinds of editors could induce broad changes in expression and splicin
Externí odkaz:
https://doaj.org/article/d7eb1dadf68045f89f9b6517005e2443
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/b15cc969cf6841e68372b838c11a7126
Autor:
Yunbo Qiao, Chao Ren, Shisheng Huang, Jie Yuan, Xingchen Liu, Jiao Fan, Jianxiang Lin, Susu Wu, Qiuzhen Chen, Xiaochen Bo, Xiangyang Li, Xingxu Huang, Zhen Liu, Wenjie Shu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Until now, the transcriptome of preimplantation mouse embryos has only been analysed by short-read sequencing. Here, the authors perform long-read sequencing to provide a more detailed transcriptome of the preimplantation mouse embryo, identifying va
Externí odkaz:
https://doaj.org/article/8037144ef5c94845a8eb375c83c2098a
Publikováno v:
Analytical Chemistry. 95:6748-6756
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::466383ba3f34c8d498e8c079644f9f5b
https://doi.org/10.1021/acs.analchem.3c00873
https://doi.org/10.1021/acs.analchem.3c00873
Autor:
Chensi Cao, Feng Liu, Hai Tan, Deshou Song, Wenjie Shu, Weizhong Li, Yiming Zhou, Xiaochen Bo, Zhi Xie
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 16, Iss 1, Pp 17-32 (2018)
Advances in biological and medical technologies have been providing us explosive volumes of biological and physiological data, such as medical images, electroencephalography, genomic and protein sequences. Learning from these data facilitates the und
Externí odkaz:
https://doaj.org/article/f39538e8327345219d9feb75d33d2ddd
Autor:
Yunbo Qiao, Chao Ren, Shisheng Huang, Jie Yuan, Xingchen Liu, Jiao Fan, Jianxiang Lin, Susu Wu, Qiuzhen Chen, Xiaochen Bo, Xiangyang Li, Xingxu Huang, Zhen Liu, Wenjie Shu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-22148-6
Externí odkaz:
https://doaj.org/article/edec88eab53c443e831af5fbe98f1037
Autor:
Wenjie Shu, Feng Liu, Shuhong Huang, Jiongsong Hu, Xiaozhou Chen, Ziguo Song, Junguo Dong, Yao Liu, Xingxu Huang, Xiaolong Wang, Shengqi Wang
Prime editors (PEs) are promising genome editing tools, but efficiency pre-testing of prime editing guide RNA (pegRNA) design is still laborious and time-consuming due to the lack of accurate and universal approaches. Here, we design a customized att
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff235338437a1da46f170b4e9d9d59ae
https://doi.org/10.21203/rs.3.rs-2340162/v1
https://doi.org/10.21203/rs.3.rs-2340162/v1
Engineering synthetic CopT/A-based genetic circuits for miRNA imaging and functional gene regulation
Synthetic genetic circuits that can operate at the transcriptional and translation levels have been widely applied in the control of cellular behaviors and functions. However, the regulation of genetic circuits is often accompanied by the introductio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e20b22703421973d2053599666676df3
https://doi.org/10.1101/2023.01.25.525516
https://doi.org/10.1101/2023.01.25.525516