Zobrazeno 1 - 10
of 839
pro vyhledávání: '"Wenhua HUANG"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder marked by cognitive decline, memory impairment, and behavioral alterations. The N-methyl-D-aspartate (NMDA) receptor has emerged as a promising target for AD pharmacother
Externí odkaz:
https://doaj.org/article/a7a1ee3893954c358e70346b0149d0b0
Autor:
Da Wang, Junsheng Chen, Guanhua Wu, Fei Xiong, Wenzheng Liu, Qi Wang, Yiyang Kuai, Wenhua Huang, Yongqiang Qi, Bing Wang, Ruizhi He, Yongjun Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Cholangiocarcinoma (CCA) is a highly malignant, rapidly progressing tumor of the bile duct. Owing to its chemoresistance, it always has an extremely poor prognosis. Therefore, detailed elucidation of the mechanisms of chemoresista
Externí odkaz:
https://doaj.org/article/1bad50f6a60849b79a8adb98f1b8a30b
Autor:
Junsheng Chen, Da Wang, Guanhua Wu, Fei Xiong, Wenzheng Liu, Qi Wang, Yiyang Kuai, Wenhua Huang, Yongqiang Qi, Bing Wang, Yongjun Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Cholangiocarcinoma (CCA) is a highly malignant tumor characterized by a lack of effective targeted therapeutic strategies. The protein UHRF1 plays a pivotal role in the preservation of DNA methylation and works synergistically wit
Externí odkaz:
https://doaj.org/article/ec3703bda7144579857e33fa9392d7ad
Autor:
Minsi Li, Yi Wei, Wenhua Huang, Cen Wang, Shixi He, Shuwen Bi, Shuangyu Hu, Ling You, Xuanping Huang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Oral squamous cell carcinoma (OSCC) has an extremely poor prognosis. Recent studies have suggested that mitophagy-related genes (MRGs) are closely correlated with the development and occurrence of cancer, but the role they play in oral cance
Externí odkaz:
https://doaj.org/article/06b89fe1122c46678597b848cbec9f3c
Publikováno v:
Geodesy and Geodynamics, Vol 15, Iss 4, Pp 366-378 (2024)
With the gradual development and modernization of satellite navigation systems, using observation information from multi-GNSS has become one of the hot-spot issues in recent years. Multi-system loose combinations form double-difference observation eq
Externí odkaz:
https://doaj.org/article/8555cd816ef54312b1cdbfb33ed330c5
Autor:
Zaopeng He, Guanghua Xu, Guodong Zhang, Zeyu Wang, Jingsong Sun, Wei Li, Dongbo Liu, Yibin Tian, Wenhua Huang, Daozhang Cai
Publikováno v:
Frontiers in Surgery, Vol 11 (2024)
BackgroundImage-guided surgical navigation systems are widely regarded as the benchmark for computer-assisted surgical robotic platforms, yet a persistent challenge remains in addressing intraoperative image drift and mismatch. It can significantly i
Externí odkaz:
https://doaj.org/article/f12f34669dea489081c80f7a312ca1f4
Autor:
Bowen Fu, Jianlin Shen, Xuenong Zou, Nian Sun, Ze Zhang, Zengping Liu, Canjun Zeng, Huan Liu, Wenhua Huang
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-15 (2024)
Abstract Extracellular matrix (ECM) stiffening is a typical characteristic of cartilage aging, which is a quintessential feature of knee osteoarthritis (KOA). However, little is known about how ECM stiffening affects chondrocytes and other molecules
Externí odkaz:
https://doaj.org/article/747c6cde39ff4f918bc8db585082ab46
Autor:
Junsheng Chen, Da Wang, Guanhua Wu, Fei Xiong, Wenzheng Liu, Qi Wang, Yiyang Kuai, Wenhua Huang, Yongqiang Qi, Bing Wang, Yongjun Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/536bdf2e1cdb490a8976e58f79beb699
Autor:
Mingrui Liu, Lincong Luo, Tao Lin, Xiaoyu Lv, Manoj Kumar Vashisth, Jiaying Li, Jianlin Shen, Lin Xu, Wenhua Huang
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
ObjectiveThis study used finite element analysis to simulate four commonly used fixation methods for metacarpal shaft oblique fractures during finger motion and evaluate their biomechanical performance. The aim was to provide evidence for clinically
Externí odkaz:
https://doaj.org/article/d2b0114436104bc3b8f1532127815ad2
Autor:
Shiyu Li, Weihan Zheng, Wenfeng Deng, Ziyue Li, Jiaxin Yang, Huihui Zhang, Zhenning Dai, Weiwei Su, Zi Yan, Wanting Xue, Xinyi Yun, Siqi Mi, Jianlin Shen, Xiang Luo, Ling Wang, Yaobin Wu, Wenhua Huang
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract To effectively treat osteoarthritis (OA), the existing inflammation must be reduced before the cartilage damage can be repaired; this cannot be achieved with a single type of extracellular vesicles (EVs). Here, a hydrogel complex with logic
Externí odkaz:
https://doaj.org/article/3ceec1407bcc4a5fbbf6d5dba560bf6e