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Akademický článek

Rapid Antigen Diagnostics as Frontline Testing in the COVID‐19 Pandemic

Autor: Jiang Xu, Liam Kerr, Yue Jiang, Wenhao Suo, Lei Zhang, Taotao Lao, Yuxin Chen, Yan Zhang

Publikováno v: Small Science, Vol 2, Iss 8, Pp n/a-n/a (2022)

The ongoing global COVID‐19 pandemic, caused by the SARS‐CoV‐2 virus, has resulted in significant loss of life since December 2019. Timely and precise virus detection has been proven as an effective solution to reduce the spread of the virus an

Externí odkaz: https://doaj.org/article/69ceb7759a6e43a0b38a6fe11d3806ac

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Dependence on the MUC1-C Oncoprotein in Classic, Variant, and Non–neuroendocrine Small Cell Lung Cancer

Autor: Atsushi Fushimi, Yoshihiro Morimoto, Satoshi Ishikawa, Nami Yamashita, Atrayee Bhattacharya, Tatsuaki Daimon, Hasan Rajabi, Caining Jin, Masayuki Hagiwara, Yota Yasumizu, Zhou Luan, Wenhao Suo, Kwok-Kin Wong, Henry Withers, Song Liu, Mark D. Long, Donald Kufe

Publikováno v: Molecular Cancer Research. 20:1379-1390

Small cell lung cancer (SCLC) is a recalcitrant malignancy defined by subtypes on the basis of differential expression of the ASCL1, NEUROD1, and POU2F3 transcription factors. The MUC1-C protein is activated in pulmonary epithelial cells by exposure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f62d1eb665d9dc53792b130d9a479b5
https://doi.org/10.1158/1541-7786.mcr-22-0165

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BPTF activates the MAPK pathway through coexpression with Raf1 to promote proliferation of T‑cell lymphoma

Autor: Dongyu, Bai, Yong, Zhou, Fayan, Shen, Dehong, Gao, Wenhao, Suo, Haiping, Zhang, Heng, Li

Publikováno v: Oncology Letters. 24

The aim of the present study was to explore the role and biological function of bromodomain PHD finger transcription factor (BPTF) in T-cell lymphoma. Reverse transcription-quantitative PCR (RT-qPCR), western blotting, immunohistochemistry and bioinf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321a7be5bb40ec8d388a6cfb94e8cd7c
https://doi.org/10.3892/ol.2022.13344

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Torin2 inhibits the EGFR-TKI resistant Non-Small Lung Cancer cell proliferation through negative feedback regulation of Akt/mTOR signaling

Autor: Yi Hu, Jiurong Li, Aiping Ma, Qun Liu, Mingyao Ke, Weixi Guo, Ji Zhang, Wenhao Suo

Publikováno v: Journal of Cancer

It is known that mammalian target of rapamycin (mTOR) signaling plays an important role in NSCLC cells proliferation. Torin2 is a second-generation ATP-competitive inhibitor which is selective for mTOR activity. In this study, we investigated whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe1e6ac80894f00a40c2b28a8597b2c
http://europepmc.org/articles/PMC7477446

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Handheld Microfluidic Filtration Platform Enables Rapid, Low‐Cost, and Robust Self‐Testing of SARS‐CoV‐2 Virus

Autor: Yan Zhang, Liam Kerr, Wenhao Suo, Jiang Xu, Johan Paulsson, Taotao Lao, Youlian Goulev, Lei Sun

Publikováno v: Small

The COVID-19 pandemic has led to an unprecedented crisis of both public health and economy. The prevention of further spread relies greatly on the timely and accurate identification of infected individuals. Here, we report of a novel microfluidic tes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71a98b16fbc00061f3525c481f39bef
https://doi.org/10.1002/smll.202104009

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