Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Wengong, Yu"'
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 10, Pp n/a-n/a (2024)
Abstract Background The transcription factor NRF2 plays a significant role in regulating genes that protect cells from oxidative damage. O‐GlcNAc modification, a type of posttranslational modification, is crucial for cellular response to stress. Al
Externí odkaz:
https://doaj.org/article/615d85d315874a748ee852ac453a2ac3
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 51, Iss 1, Pp 509-519 (2023)
AbstractHelicobacter pylori (H. pylori) is recognized as a pathogen associated with several gastrointestinal diseases. The current treatments exhibit numerous drawbacks, including antibiotic resistance. H. pylori can adhere to and colonize the gastri
Externí odkaz:
https://doaj.org/article/5f00c2468f9040d6839460e1cacf7747
Autor:
Nannan Song, Xian Guan, Siqi Zhang, Yanqing Wang, Xuekai Wang, Zhongxia Lu, Daochen Chong, Jennifer Yiyang Wang, Rilei Yu, Wengong Yu, Tao Jiang, Yuchao Gu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-14 (2023)
Abstract Pancreatic cancer is a highly aggressive cancer, and is primarily treated with gemcitabine, with increasing resistance. SIRT6 as a member of sirtuin family plays important roles in lifespan and diverse diseases, such as cancer, diabetes, inf
Externí odkaz:
https://doaj.org/article/938516f9a4984d6f9d828e81d45d9846
Autor:
Xiaozhi Xi, Guokai Xiao, Guiqi An, Lin Liu, Xiaochun Liu, Peiyu Hao, Jennifer Yiyang Wang, Dandan Song, Wengong Yu, Yuchao Gu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionO-GlcNAcylation is a type of reversible post-translational modification on Ser/Thr residues of intracellular proteins in eukaryotic cells, which is generated by the sole O-GlcNAc transferase (OGT) and removed by O-GlcNAcase (OGA). Thousan
Externí odkaz:
https://doaj.org/article/3ec2e63bc1a143a7841dc72649b6c7af
Publikováno v:
Marine Drugs, Vol 21, Iss 10, p 517 (2023)
Angiogenesis refers to the process of growing new blood vessels from pre-existing capillaries or post-capillary veins. This process plays a critical role in promoting tumorigenesis and metastasis. As a result, developing antiangiogenic agents has bec
Externí odkaz:
https://doaj.org/article/63f65bfa12684d6d8ed0f1e9c4902292
Publikováno v:
Marine Drugs, Vol 21, Iss 5, p 296 (2023)
Pseudomonas aeruginosa is an opportunistic pathogen that infects patients by regulating virulence factors and biofilms through a quorum sensing (QS) system to protect itself from antibiotics and environmental stress. Therefore, the development of quo
Externí odkaz:
https://doaj.org/article/8ea28865935345f3a4c4dba0061c06ed
Publikováno v:
Biotechnology for Biofuels, Vol 13, Iss 1, Pp 1-17 (2020)
Abstract Background As the most abundant polysaccharide in brown algae, alginate has become a promising economical material for bioethanol production. Recently, exo-type alginate lyases have received extensive attention because the unsaturated monosa
Externí odkaz:
https://doaj.org/article/98490e6d21e8452387df23e6e4566d76
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
Carbohydrate-binding modules (CBMs), as an important auxiliary module, play a key role in degrading soluble alginate by alginate lyase, but the function on alginate gel has not been elucidated. Recently, we reported alginate lyase VxAly7B containing
Externí odkaz:
https://doaj.org/article/5d6625ea0b374da8a9e7b9fc9b14edc6
Publikováno v:
Marine Drugs, Vol 21, Iss 1, p 6 (2022)
Alginate oligosaccharides (AOS) and their derivatives become popular due to their favorable biological activity, and the key to producing functional AOS is to find efficient alginate lyases. This study showed one alginate lyase TsAly7A found in Thala
Externí odkaz:
https://doaj.org/article/999b6ad08cbb4d298aa57326c815e218
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Hyaluronic acid (HA) is a negatively charged and linear polysaccharide existing in the tissues and body fluids of all vertebrates. Some pathogenic bacteria target hyaluronic acid for adhesion and/or infection to host cells. Vibrio alginolyticus is an
Externí odkaz:
https://doaj.org/article/5350961bcb714c51b1854f070bd67b8e