Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Wengang Chai"'
Autor:
Marie N. Sorin, Antonio Di Maio, Lisete M. Silva, Domenic Ebert, Clément P. Delannoy, Ngoc-Khanh Nguyen, Yann Guerardel, Wengang Chai, Franck Halary, Karine Renaudin-Autain, Yan Liu, Céline Bressollette-Bodin, Thilo Stehle, Dorian McIlroy
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112114- (2023)
Summary: BK polyomavirus (BKPyV) is an opportunistic pathogen that uses the b-series gangliosides GD1b and GT1b as entry receptors. Here, we characterize the impact of naturally occurring VP1 mutations on ganglioside binding, VP1 protein structure, a
Externí odkaz:
https://doaj.org/article/589cd137d26c40f086153d37f326313b
Autor:
Viviana G. Correia, Filipa Trovão, Benedita A. Pinheiro, Joana L. A. Brás, Lisete M. Silva, Cláudia Nunes, Manuel A. Coimbra, Yan Liu, Ten Feizi, Carlos M. G. A. Fontes, Barbara Mulloy, Wengang Chai, Ana Luísa Carvalho, Angelina S. Palma
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT A multigene polysaccharide utilization locus (PUL) encoding enzymes and surface carbohydrate (glycan)-binding proteins (SGBPs) was recently identified in prominent members of Bacteroidetes in the human gut and characterized in Bacteroides ov
Externí odkaz:
https://doaj.org/article/24f151b72651473cb81a3329848e3bea
Autor:
Chuncui Huang, Zeshun Tan, Keli Zhao, Wenjun Zou, Hui Wang, Huanyu Gao, Shiwei Sun, Dongbo Bu, Wengang Chai, Yan Li
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103272- (2021)
Summary: The densely glycosylated spike (S) protein highly exposed on severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) surface mediates host cell entry by binding to the receptor angiotensin-converting enzyme 2 (ACE2). However, the role o
Externí odkaz:
https://doaj.org/article/2d0562f6489549838ba1b3d9e2be89f3
Autor:
Ingrida Vendele, Janet A Willment, Lisete M Silva, Angelina S Palma, Wengang Chai, Yan Liu, Ten Feizi, Maria Spyrou, Mark H T Stappers, Gordon D Brown, Neil A R Gow
Publikováno v:
PLoS Pathogens, Vol 16, Iss 1, p e1007927 (2020)
During the course of fungal infection, pathogen recognition by the innate immune system is critical to initiate efficient protective immune responses. The primary event that triggers immune responses is the binding of Pattern Recognition Receptors (P
Externí odkaz:
https://doaj.org/article/c5fa6d5b4b9d4571b6a61e868c7112d8
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 2007-2014 (2018)
Combinational therapy is usually considered as a preferable approach for effective cancer therapy. Especially, combinational chemotherapies targeting different molecular targets are of particular interest due to its high flexibility as well as effici
Externí odkaz:
https://doaj.org/article/740fae5ac1cd4e2393ea8dd47d31da8c
Autor:
Naresh Chandra, Yan Liu, Jing-Xia Liu, Lars Frängsmyr, Nian Wu, Lisete M Silva, Mona Lindström, Wengang Chai, Fatima Pedrosa Domellöf, Ten Feizi, Niklas Arnberg
Publikováno v:
Viruses, Vol 11, Iss 3, p 247 (2019)
Glycans on plasma membranes and in secretions play important roles in infection by many viruses. Species D human adenovirus type 37 (HAdV-D37) is a major cause of epidemic keratoconjunctivitis (EKC) and infects target cells by interacting with sialic
Externí odkaz:
https://doaj.org/article/03416e5acfc64e399d87166d5bc0c404
Autor:
Su Ma, Gaofei Duan, Wengang Chai, Cunliang Geng, Yulong Tan, Lushan Wang, Frédéric Le Sourd, Gurvan Michel, Wengong Yu, Feng Han
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64666 (2013)
ι-Carrageenases belong to family 82 of glycoside hydrolases that degrade sulfated galactans in the red algae known as ι-carrageenans. The catalytic mechanism and some substrate-binding residues of family GH82 have been studied but the substrate rec
Externí odkaz:
https://doaj.org/article/75420a985862409ba16a36af1a5c3f53
Autor:
Shuai Wang, Xun Huang, Danni Sun, Xianliang Xin, Qiuming Pan, Shuying Peng, Zhongjie Liang, Cheng Luo, Yiming Yang, Hualiang Jiang, Min Huang, Wengang Chai, Jian Ding, Meiyu Geng
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37427 (2012)
O-linked N-acetylglucosamine glycosylations (O-GlcNAc) and O-linked phosphorylations (O-phosphate), as two important types of post-translational modifications, often occur on the same protein and bear a reciprocal relationship. In addition to the wel
Externí odkaz:
https://doaj.org/article/d18a3366658449a5b41ebf30bd998a72
Autor:
Livia Lai, Janene Bumstead, Yan Liu, James Garnett, Maria A Campanero-Rhodes, Damer P Blake, Angelina S Palma, Wengang Chai, David J P Ferguson, Peter Simpson, Ten Feizi, Fiona M Tomley, Stephen Matthews
Publikováno v:
PLoS Pathogens, Vol 7, Iss 10, p e1002296 (2011)
Eimeria spp. are a highly successful group of intracellular protozoan parasites that develop within intestinal epithelial cells of poultry, causing coccidiosis. As a result of resistance against anticoccidial drugs and the expense of manufacturing li
Externí odkaz:
https://doaj.org/article/c70bcb58d5574c36909373271913d67c
Autor:
Zhongqi Fan, Meishan Jin, Lei Zhang, Nanya Wang, Mingyue Li, Chuanlei Wang, Feng Wei, Ping Zhang, Xiaohong Du, Xiaodong Sun, Wei Qiu, Meng Wang, Hongbin Wang, Xiaoju Shi, Junfeng Ye, Chao Jiang, Jianpeng Zhou, Wengang Chai, Jun Qi, Ting Li
Publikováno v:
Gut; Nov2023, Vol. 72 Issue 11, p2149-2163, 43p