Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Wenfang Lai"'
Autor:
Yaping Chen, Zheming Chen, Weineng Cheng, Yajun Cao, Wen Xu, Wenfang Lai, Yuqin Zhang, Mei Huang, Lihong Nan
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 10, p 296 (2022)
Background: Endoplasmic reticulum stress (ERS) is a key part of the apoptotic cascade that is initiated after cerebral ischemia-reperfusion injury and is very important for research on poststroke rehabilitation. In addition, the unfolded protein resp
Externí odkaz:
https://doaj.org/article/f07fb9cd2f09401ea0794b758c9eb4f8
Autor:
Lihong Nan, Mei Huang, Yuqin Zhang, Wenfang Lai, Wen Xu, Yajun Cao, Weineng Cheng, Zheming Chen, Yaping Chen
Publikováno v:
Frontiers in bioscience (Landmark edition). 27(10)
Endoplasmic reticulum stress (ERS) is a key part of the apoptotic cascade that is initiated after cerebral ischemia-reperfusion injury and is very important for research on poststroke rehabilitation. In addition, the unfolded protein response (UPR) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a357b22cc03c50fcd9b75136afa0b0e
https://pubmed.ncbi.nlm.nih.gov/36336865
https://pubmed.ncbi.nlm.nih.gov/36336865
Autor:
Huang Li, Zheming Chen, Qingqing Xie, Yaping Chen, Yuqin Zhang, Yan Chen, Mei Huang, Wenfang Lai, Lihong Nan
Publikováno v:
Neurochemical Research. 45:278-294
Cerebral ischemia-reperfusion injury is a complex pathophysiological process. Poly(ADP-ribose) (PAR) polymerase-1 (PARP-1)/apoptosis-inducing factor (AIF) signaling pathway-mediated apoptosis is one of the non-caspase-dependent cell death programs th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a5487e7e6dae42513d13a6e773c568
https://doi.org/10.1007/s11064-019-02912-3
https://doi.org/10.1007/s11064-019-02912-3
Publikováno v:
Inflammation. 42:1830-1842
Salidroside, an active constituent of Rhodiola rosea, is neuroprotective after transient middle cerebral artery occlusion (tMCAO). However, its effects in other experimental stroke models are less understood. Here, we investigated the effect of daily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b699d4c7f8aa87e73b8b878da47a02a
https://doi.org/10.1007/s10753-019-01045-7
https://doi.org/10.1007/s10753-019-01045-7
Autor:
Kedan Chu, John Brown, Yang Zelin, Huang Xin, Yuheng Tang, Guizhu Hong, Yingzheng Wang, Wenfang Lai, Junjie Liu
Publikováno v:
European journal of medicinal chemistry. 209
Salidroside [(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenethoxy)tetrahy-dro-2H-pyran-3,4,5-triol] is an antioxidant, anti-inflammatory and neuroprotective agent, but its drug-like properties are unoptimized and its mechanism of actions is unce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4283df3d183030d1b42e510ae2af6a
https://pubmed.ncbi.nlm.nih.gov/33097301
https://pubmed.ncbi.nlm.nih.gov/33097301
Publikováno v:
International Journal of Nanomedicine
Yu Song,1,2 Han Cai,1 Tingjie Yin,1 Meirong Huo,1 Ping Ma,3 Jianping Zhou,1 Wenfang Lai2 1Department of Pharmaceutics, China Pharmaceutical University, Nanjing, People’s Republic of China; 2College of Pharmacy, Fujian University of Traditional Chin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45da0972bddc2485d786f0cc7c0de876
https://doi.org/10.2147/ijn.s155383
https://doi.org/10.2147/ijn.s155383
Autor:
Yicong Wei, Yingzheng Wang, Haimian Hong, Guizhu Hong, Chen Lidian, Xiaoqin Zhang, John Brown, Kedan Chu, Wenfang Lai
Publikováno v:
Inflammation. 40:1297-1309
Salidroside is being investigated for its therapeutic potential in stroke because it is neuroprotective over an extended therapeutic window of time. In the present study, we investigated the mechanisms underlying the anti-inflammatory effects of sali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd182f16219bbba0c6d3d3f835a314b5
https://doi.org/10.1007/s10753-017-0573-x
https://doi.org/10.1007/s10753-017-0573-x
Publikováno v:
Inflammation. 43(1)
Salidroside, an active component of Rhodiola rosea, reduces inflammation and neuronal damage after middle cerebral artery occlusion (MCAO) with reperfusion, partly by inhibiting cerebral complement C3 activation. However, the mechanisms of this inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04012ce954f1cf3762e9e3d94142e062
https://pubmed.ncbi.nlm.nih.gov/31701353
https://pubmed.ncbi.nlm.nih.gov/31701353
Autor:
Qingxia Qin, Haiyu Zhao, Erxin Shang, Na Lin, Wenfang Lai, Hongwei Zhu, Yuhua Fang, Ya Lin, Yanqiong Zhang
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2016 (2016)
We investigated the therapeutic role of the herbal combinationEuphorbia kansui(GS) andGlycyrrhiza(GC) in ascites during hepatocellular carcinoma (HCC). The AVPR2 and AQP2 expression in kidney tissues of ascites mice in different groups was determined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1199437cceb78e4166bfcfe9080d4bf1
https://doi.org/10.1155/2016/7620817
https://doi.org/10.1155/2016/7620817
Autor:
Chen Lidian, Yingzheng Wang, Kedan Chu, John Brown, Wenfang Lai, Guizhu Hong, Xiaoqin Zhang, Xie Xiuli
Publikováno v:
Inflammation. 41(2)
Salidroside is neuroprotective across a wide therapeutic time-window after cerebral ischemia-reperfusion injury (IRI). Here, we investigated the role of complement in mediating effects of salidroside after cerebral IRI in rats. Rats were administrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fe427acfb76e7e73ff7ca041eb8b95
https://pubmed.ncbi.nlm.nih.gov/29198014
https://pubmed.ncbi.nlm.nih.gov/29198014