Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Wendy Zinzow-Kramer"'
Publikováno v:
The Journal of Immunology. 208:167.12-167.12
Naive T cells constantly experience tonic or basal TCR signals in response to self-peptides presented by MHC (pMHC) in vivo. We aimed to define how tonic TCR signaling impacts naive CD4+ T cells at the functional, transcriptional, and epigenetic leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7366a871e464e259d3ec1b539c599091
https://doi.org/10.4049/jimmunol.208.supp.167.12
https://doi.org/10.4049/jimmunol.208.supp.167.12
Publikováno v:
The Journal of Immunology. 204:150.2-150.2
Prior to their activation with high affinity foreign peptides presented by MHC Class II (pMHC), naïve CD4+ T cells experience weak “tonic” or “basal” T cell receptor (TCR) signals in response to self-pMHC. We used a combination of the Nur77-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a4cd48f9fd4fc76049d14183a58b8cf
https://doi.org/10.4049/jimmunol.204.supp.150.2
https://doi.org/10.4049/jimmunol.204.supp.150.2
Autor:
Wendy Zinzow-Kramer, Alyssa Long, Kristen Rosenthal, Royce Butler, Brian Evavold, Jeremy Boss
Publikováno v:
The Journal of Immunology. 186:109.10-109.10
Antigen presenting cells (APCs) constitutively express major histocompatibility complex class II (MHC-II) molecules, a crucial component of an organism’s adaptive immune response. Mutations in the master regulator of MHC-II (CIITA) are found in a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99a5c4d6c30a6c0f248207e1c90c041b
https://doi.org/10.4049/jimmunol.186.supp.109.10
https://doi.org/10.4049/jimmunol.186.supp.109.10