Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Wendy Xiong"'
Autor:
Siqing Fu, Vivek Subbiah, Wendy Xiong, Shreyaskumar Patel, Sarina Anne Piha-Paul, Filip Janku, Aung Naing, Daniel D. Karp, Funda Meric-Bernstam, Nizar M. Tannir, Li Xu, Binoj Nair, Najat C. Daw, Ralph Zinner, Rosa Mostorino, Ecaterina Elena Dumbrava, David S. Hong
Publikováno v:
OncoTargets and therapy
Sarina A Piha-Paul,1 Ecaterina E Dumbrava,1 Binoj C Nair,1 Wendy Xiong,1 Li Xu,1 Rosa Mostorino,1 Vivek Subbiah,1 Nizar Tannir,2 Siqing Fu,1 Aung Naing,1 Filip Janku,1 Daniel D Karp,1 Shreyaskumar Patel,3 Najat C Daw,4 David Hong,1 Funda Meric-Bernst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1458ddf385ef4229b891c0747475af51
http://europepmc.org/articles/PMC8114359
http://europepmc.org/articles/PMC8114359
Autor:
Suma Gopinathan, Kenneth G. Carson, Alan G. E. Wilson, Zhi-Ming Ding, Bryce Alden Harrison, Damaris S. Diaz, Angela L. Harris, Debra Bruce, Nicole Cathleen Goodwin, Emily O’Neill, David R. Powell, Melinda Smith, Eric Strobel, David B. Rawlins, Wendy Xiong, Ling Li, Andrea Y. Thompson, Mary Thiel, Faika Mseeh
Publikováno v:
Journal of Medicinal Chemistry. 60:710-721
The increasing number of people afflicted with diabetes throughout the world is a major health issue. Inhibitors of the sodium-dependent glucose cotransporters (SGLT) have appeared as viable therapeutics to control blood glucose levels in diabetic pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8541b1a58e42776d5a5b4773e40351f7
https://doi.org/10.1021/acs.jmedchem.6b01541
https://doi.org/10.1021/acs.jmedchem.6b01541
Publikováno v:
Bone. 145
Hip fractures at the femoral neck are a major cause of morbidity and mortality, but aside from biomechanical strength testing, little is known about femoral neck architecture in mice. Procedures were optimized to analyze high-resolution (6 μm voxel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea74cddc3e15fb714e0c39055d08a5c0
https://pubmed.ncbi.nlm.nih.gov/31437568
https://pubmed.ncbi.nlm.nih.gov/31437568
Autor:
Alan Wilson, Angela L. Harris, Brian Zambrowicz, Wendy Xiong, Christopher M. DaCosta, David R. Powell, Bryce Alden Harrison, Nicole Cathleen Goodwin, Melinda Smith, Sabrina Jeter-Jones, Andrea Y. Thompson, Eric Strobel, Faika Mseeh, David B. Rawlins, Jennifer Greer, Deon Doree, Suma Gopinathan, Kenneth G. Carson, Zhi-Ming Ding
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 362(1)
LX2761 is a potent sodium/glucose cotransporter 1 inhibitor restricted to the intestinal lumen after oral administration. Studies presented here evaluated the effect of orally administered LX2761 on glycemic control in preclinical models. In healthy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38140540d80f7939267c966c2d73c1da
https://pubmed.ncbi.nlm.nih.gov/28442582
https://pubmed.ncbi.nlm.nih.gov/28442582
Autor:
Henry Wu, Qunfang Wan, Brenda Ngo, Peng Peng, Wendy Xiong, Sarina Anne Piha-Paul, Xiaoju Yang, Frank S. Wu
Publikováno v:
Journal of Clinical Oncology. 37:TPS3168-TPS3168
TPS3168 Background: Multi-target kinase inhibitors have gained increasing attention in the past few years due to their capabilities of simultaneously targeting several hallmarks of cancer. Triple negative breast cancer (TNBC), the most aggressive typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c056c219dacb1a9ade06338a4fb536af
https://doi.org/10.1200/jco.2019.37.15_suppl.tps3168
https://doi.org/10.1200/jco.2019.37.15_suppl.tps3168
Autor:
Milind Javle, Siqing Fu, Timothy A. Yap, Aung Naing, Tyler J. Moss, David S. Hong, Sarina Anne Piha-Paul, Daniel D. Karp, Jordi Rodon, Rosa Mostorino, Funda Meric-Bernstam, Shubham Pant, Vivek Subbiah, Wendy Xiong, Apostolia-Maria Tsimberidou, Filip Janku, Shelby Sedelmeier, Kenna R. Shaw, Karina Eterovic, Coya Tapia, Gordon B. Mills, Kenneth R. Hess
Publikováno v:
Molecular Cancer Therapeutics. 17:A096-A096
Background: Cancer cells deficient in BRCA1/2 are selectively sensitive to the double-stranded DNA breaks induced by poly (ADP-ribose) polymerase (PARP) inhibitors. Multiple ongoing trials are evaluating PARP inhibitors in patients with breast, ovari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d5d387df80226775e8d3b69f3646a04
https://doi.org/10.1158/1535-7163.targ-17-a096
https://doi.org/10.1158/1535-7163.targ-17-a096
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 108:137-148
Using a luciferase reporter assay we found that human serum transactivated the ileal apical sodium-dependent bile acid transporter (ASBT) promoter three to fourfold. Confirming this effect, addition of human serum to both Caco-2 cells and fresh human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ae97a6e5b0e51afa981a7cc01e7e6b
https://doi.org/10.1016/j.jsbmb.2007.07.005
https://doi.org/10.1016/j.jsbmb.2007.07.005
Publikováno v:
Biochimica et biophysica acta. 1771(11)
Using a luciferase reporter assay in both LMH cells and Caco2 cells we found that certain bile acids including unconjugated deoxycholic and others transactivated the ileal apical sodium-dependent bile acid transporter (ASBT) at concentrations ranging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4654d30dc0f935cde133befef7816188
https://pubmed.ncbi.nlm.nih.gov/17964214
https://pubmed.ncbi.nlm.nih.gov/17964214
Autor:
Anthony Person, Wendy Xiong, Christian Erickson, Kate Shields, Jun Li, Ming BI, Guoping Wu, Vassili Kalabokis
Publikováno v:
The Journal of Immunology. 194:54.26-54.26
Angiopoietins and Angiopoietin-like (ANGPTL) proteins are secreted glycoproteins that play multiple roles in angiogenesis, lipid metabolism, hematopoietic stem cell expansion, and inflammation. Unlike Angiopoietins, which are known to signal through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7774b32d3f14988a160041d5760674d0
https://doi.org/10.4049/jimmunol.194.supp.54.26
https://doi.org/10.4049/jimmunol.194.supp.54.26
Autor:
Goodwin, Nicole C., Zhi-Ming Ding, Harrison, Bryce A., Strobel, Eric D., Harris, Angela L., Smith, Melinda, Thompson, Andrea Y., Wendy Xiong, Mseeh, Faika, Bruce, Debra J., Diaz, Damaris, Gopinathan, Suma, Ling Li, O'Neill, Emily, Thiel, Mary, Wilson, Alan G. E., Carson, Kenneth G., Powell, David R., Rawlins, David B.
Publikováno v:
Journal of Medicinal Chemistry; Jan2017, Vol. 60 Issue 2, p710-721, 12p