Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Wendy Xin"'
Autor:
Gabrielle L. Sell, Wendy Xin, Emily K. Cook, Mark A. Zbinden, Thomas B. Schaffer, Robert N. O’Meally, Robert N. Cole, Seth S. Margolis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract In humans, loss-of-function mutations in the UBE3A gene lead to the neurodevelopmental disorder Angelman syndrome (AS). AS patients have severe impairments in speech, learning and memory, and motor coordination, for which there is currently
Externí odkaz:
https://doaj.org/article/65582c1636854f608ecc07c0e17a093b
Autor:
Kae-Jiun Chang, Ira Agrawal, Anna Vainshtein, Wan Yun Ho, Wendy Xin, Greg Tucker-Kellogg, Keiichiro Susuki, Elior Peles, Shuo-Chien Ling, Jonah R Chan
Publikováno v:
eLife, Vol 10 (2021)
TDP-43 is extensively studied in neurons in physiological and pathological contexts. However, emerging evidence indicates that glial cells are also reliant on TDP-43 function. We demonstrate that deletion of TDP-43 in Schwann cells results in a drama
Externí odkaz:
https://doaj.org/article/806e78a46128409587bd9290f6d060f7
Autor:
Wendy Xin, Yevgeniya A. Mironova, Hui Shen, Rosa A.M. Marino, Ari Waisman, Wouter H. Lamers, Dwight E. Bergles, Antonello Bonci
Publikováno v:
Cell Reports, Vol 27, Iss 8, Pp 2262-2271.e5 (2019)
Summary: Glutamate has been implicated in a wide range of brain pathologies and is thought to be metabolized via the astrocyte-specific enzyme glutamine synthetase (GS). We show here that oligodendrocytes, the myelinating glia of the central nervous
Externí odkaz:
https://doaj.org/article/a06ba1c26c6e48aba282f87bd4551c61
Autor:
Wendy Xin, Antonello Bonci
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
In recent years, the role of astrocytes in shaping neuronal signaling has come to the forefront of neuroscience research. The development of genetic tools that enable targeted manipulation of astrocytes has revealed a wealth of mechanisms by which th
Externí odkaz:
https://doaj.org/article/c6ffa31ec8fe4fc5a697d668205fca0c
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e65463 (2013)
Contactin-1 has been shown to promote cancer metastasis. However, the underlying mechanisms remain unclear. We report here that knockdown of contactin-1 in A549 lung cancer cells reduced A549 cell invasion and the cell's ability to grow in soft agar
Externí odkaz:
https://doaj.org/article/74d0736440ef47fcbcd15951dedfced6
Autor:
Christian Cordano, Jung H Sin, Garrett Timmons, Hao H Yiu, Karin Stebbins, Caroline Guglielmetti, Andres Cruz-Herranz, Wendy Xin, Daniel Lorrain, Jonah R Chan, Ari J Green
Publikováno v:
Brain : a journal of neurology, vol 145, iss 11
Brain
Brain
Many biomarkers in clinical neuroscience lack pathological certification. This issue is potentially a significant contributor to the limited success of neuroprotective and neurorestorative therapies for human neurological disease—and is evident eve
Autor:
Wendy, Xin, Jonah R, Chan
Publikováno v:
Nature neuroscience. 25(10)
Autor:
Thomas B. Schaffer, Seth S. Margolis, Mark A. Zbinden, Robert N. O'Meally, Gabrielle L. Sell, Robert N. Cole, Emily K. Cook, Wendy Xin
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific reports, vol 11, iss 1
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific reports, vol 11, iss 1
In humans, loss-of-function mutations in the UBE3A gene lead to the neurodevelopmental disorder Angelman syndrome (AS). AS patients have severe impairments in speech, learning and memory, and motor coordination, for which there is currently no treatm
Autor:
Jonah R. Chan, Wendy Xin
Publikováno v:
Immunity
Multiple sclerosis (MS) is a demyelinating, autoimmune disease of the central nervous system. While work has focused on myelin and axon loss in MS, less is known about mechanisms underlying synaptic changes. Using postmortem human MS tissue, a precli
Autor:
Wendy Xin
Publikováno v:
Victorian Literature and Culture. 47:645-649
Even before I heard about this celebration of Elaine Freedgood's work and mentorship, I was already thinking about how I'd come to know her and about the numerous ways she has shaped my writing and my writing life. This reflection was prompted, inadv