Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Wendy W. C. van Maren"'
Autor:
Erika Fletcher, Jasper Dinkelaar, Sara M. Mangsbo, Wendy W. C. van Maren, Jeroen D. C. Codée, Cornelis J. M. Melief, Jan W. Drijfhout, Robert A. Cordfunke, Gijs A. van der Marel, Ferry Ossendorp
Publikováno v:
Journal of Immunology, 201(1), 87-97
Journal of Immunology
Journal of Immunology
Enhancing T cell responses against both viral and tumor Ags requires efficient costimulation and directed delivery of peptide Ags into APCs. Long peptide vaccines are considered favorable vaccine moieties from a clinical perspective, as they can harb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87bf418753d5337138a47869e4162c5
https://hdl.handle.net/1887/96271
https://hdl.handle.net/1887/96271
Autor:
Thorbald van Hall, Sandra H. van Heiningen, Jan Willem Kleinovink, Ngaisah Klar, Margot M. Linssen, Jos van der Kaa, Jill W. C. Claassens, Lucia Daxinger, Daniela C.F. Salvatori, Cees van Kooten, Vanessa van Harmelen, Marieke F. Fransen, Chris Coward, Qingshun Lin, Ferry Ossendorp, Heng Sheng Sow, J. Sjef Verbeek, Marcel Camps, Kutty Selva Nandakumar, Lianne van Beek, Wendy W. C. van Maren, Kelly K. D. Vonk, Rikard Holmdahl, Conny Brouwers, Cor Breukel, Hreinn Benonisson, Sachiko Hirose, Piero Mastroeni
Publikováno v:
Journal of Immunology, 200(8), 2615-2626
By their interaction with IgG immune complexes, FcγR and complement link innate and adaptive immunity, showing functional redundancy. In complement-deficient mice, IgG downstream effector functions are often impaired, as well as adaptive immunity. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcbc298b92bd156bc9b3ff6875464e48
https://doi.org/10.4049/jimmunol.1700429
https://doi.org/10.4049/jimmunol.1700429
Autor:
Jeroen D. C. Codée, Ferry Ossendorp, Sara M. Mangsbo, Cornelis J. M. Melief, Kahina Ouchaou, Wendy W. C. van Maren, Erika Fletcher, Inken Dillmann, Jasper Dinkelaar, Gijs A. van der Marel, Jan W. Drijfhout, P. Hoogerhout, Robert A. Cordfunke, Anke Redeker
Publikováno v:
Molecular immunology, 93, 115-124
Molecular Immunology, 93, 115-124
Molecular Immunology
Molecular Immunology, 93, 115-124
Molecular Immunology
Immune complexes are potent mediators of cellular immunity and have been extensively studied for their disease mediating properties in humans and for their role in anti-cancer immunity. However, a viable approach to use antibody-complexed antigen as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe325d123e58e44a567987ebdfcc7d5
https://doi.org/10.1016/j.molimm.2017.11.004
https://doi.org/10.1016/j.molimm.2017.11.004
Autor:
Ingrid E.C. Verhaart, Ari Waisman, J. Sjef Verbeek, Jan W. Drijfhout, Sara M. Mangsbo, Nadine van Montfoort, Ferry Ossendorp, Marcel Camps, Cornelis J. M. Melief, Wendy W. C. van Maren
Publikováno v:
European Journal of Immunology, 42(3), 598-606. Wiley-VCH
European Journal of Immunology, 42(3), 598-606
European Journal of Immunology, 42(3), 598-606
Increasing evidence suggests that antibodies can have stimulatory effects on T-cell immunity. However, the contribution of circulating antigen-specific antibodies on MHC class I cross-priming in vivo has not been conclusively established. Here, we de
Autor:
Sebastian Amigorena, Eric Jansen, Gosse J. Adema, Carl G. Figdor, Ingrid S. Zeelenberg, Alie van der Schaaf, Wendy W. C. van Maren, Maaike A. van Hout-Kuijer, Clotilde Théry, Alexandre Boissonnas, Martijn H. den Brok, Jori A. L. Wagenaars
Publikováno v:
Journal of Immunology, 187, 3, pp. 1281-8
Journal of Immunology, 187, 1281-8
Journal of Immunology, 187, 1281-8
Effective antitumor immunotherapy requires the identification of suitable target Ags. Interestingly, many of the tumor Ags used in clinical trials are present in preparations of secreted tumor vesicles (exosomes). In this study, we compared T cell re
Autor:
Jojanneke Heidema, Grada M. van Bleek, Jan L. L. Kimpen, Michaël V. Lukens, Eva Scheltens, John W. A. Rossen, Wendy W. C. van Maren, Mariette E. G. Kranendonk, Marianne S. Ketel, Henny G. Otten, Anton M. van Loon
Publikováno v:
Journal of Immunology, 181, 5551-9
Journal of Immunology, 181(8), 5551. American Association of Immunologists
University of Groningen
Journal of Immunology, 181(8), 5551-5559. AMER ASSOC IMMUNOLOGISTS
Journal of Immunology, 181, 8, pp. 5551-9
Journal of Immunology, 181(8), 5551. American Association of Immunologists
University of Groningen
Journal of Immunology, 181(8), 5551-5559. AMER ASSOC IMMUNOLOGISTS
Journal of Immunology, 181, 8, pp. 5551-9
Contains fulltext : 70459.pdf (Publisher’s version ) (Closed access) We determined the dynamics of CD8(+) T cells specific for influenza virus and respiratory syncytial virus in blood and tracheostoma aspirates of children during the course of resp
Autor:
Sara M. Mangsbo, Erika Fletcher, Jasper Dinkelaar, Jeroen D. C. Codée, Jan W. Drijfhout, Cornelis J. M. Melief, Ferry Ossendorp, Wendy W. C. van Maren, Gijs van de Marel, Robert A. Cordfunke, Ricardo Castelli
Publikováno v:
Cancer Research. 77:1693-1693
The ability of dendritic cells (DCs) to boost an antigen-specific immune response is utilized in several cancer immunotherapy strategies including therapeutic vaccination using long peptides. Naked peptides are rapidly degraded and oil-based delivery
Autor:
J. Sjef Verbeek, Cornelis J. M. Melief, Sandra H. van Heiningen, Wendy W. C. van Maren, Esther D. Quakkelaar, Marieke F. Fransen, Ferry Ossendorp, Nikki M. Loof, Joost Vaneman
Publikováno v:
Journal of Immunology, 192(12), 5813-5820. American Association of Immunologists
Journal of Immunology, 192(12), 5813-5820
Quakkelaar, E D, Fransen, M F, van Maren, W W C, Vaneman, J, Loof, N M, van Heiningen, S H, Verbeek, J S, Ossendorp, F & Melief, C J M 2014, ' IgG-mediated anaphylaxis to a Synthetic long peptide vaccine containing a B cell epitope can be avoided by slow-release formulation ', Journal of Immunology, vol. 192, no. 12, pp. 5813-5820 . https://doi.org/10.4049/jimmunol.1302337
Journal of Immunology, 192(12), 5813-5820
Quakkelaar, E D, Fransen, M F, van Maren, W W C, Vaneman, J, Loof, N M, van Heiningen, S H, Verbeek, J S, Ossendorp, F & Melief, C J M 2014, ' IgG-mediated anaphylaxis to a Synthetic long peptide vaccine containing a B cell epitope can be avoided by slow-release formulation ', Journal of Immunology, vol. 192, no. 12, pp. 5813-5820 . https://doi.org/10.4049/jimmunol.1302337
Synthetic long peptides (SLP) are a promising vaccine modality to induce therapeutic T cell responses in patients with chronic infections and tumors. We studied different vaccine formulations in mice using SLP derived from carcinoembryonic Ag. We dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b5a48d1731c579a530abcaf04ccecc
https://research.vumc.nl/en/publications/b8099e58-34d6-4e64-812e-78193c0b6752
https://research.vumc.nl/en/publications/b8099e58-34d6-4e64-812e-78193c0b6752
Autor:
Roger P.M. Sutmuller, Wendy W. C. van Maren, Gosse J. Adema, Liza W.J. Toonen, Judith M. Bolscher, Stefan Nierkens
Publikováno v:
BMC Immunology, 12, pp. 23-23
BMC Immunology
BMC Immunology, 12, 23-23
BMC Immunology, Vol 12, Iss 1, p 23 (2011)
BMC Immunology
BMC Immunology, 12, 23-23
BMC Immunology, Vol 12, Iss 1, p 23 (2011)
Background Regulatory T cells (Treg) play a crucial role in maintaining immune homeostasis and self-tolerance. The immune suppressive effects of Tregs should however be limited in case effective immunity is required against pathogens or cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489c749d0723ada110567d86531a61e2
https://hdl.handle.net/2066/97133
https://hdl.handle.net/2066/97133
Autor:
Theo S. Plantinga, Leo A. B. Joosten, Wendy W. C. van Maren, Gosse J. Adema, Johan Garssen, Belinda Van't Land, Marjolijn Hameetman, Stefan Nierkens, Mihai G. Netea, Dirk J. de Jong, Jeroen van Bergenhenegouwen, Cor Jacobs
Publikováno v:
Clinical and Vaccine Immunology, 18, 621-8
Clinical and Vaccine Immunology, 18, 4, pp. 621-8
Clinical and Vaccine Immunology, 18, 4, pp. 621-8
The use of probiotics as a food supplement has gained tremendous interest in the last few years as beneficial effects were reported in gut homeostasis and nutrient absorption but also in immunocompromised patients, supporting protection from coloniza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822852f503c33d9f1257f7441c896f86
http://hdl.handle.net/2066/97823
http://hdl.handle.net/2066/97823