Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Wendy W J Unger"'
Autor:
Wendy W J Unger, Todd Pearson, Joana R F Abreu, Sandra Laban, Arno R van der Slik, Sacha Mulder-van der Kracht, Michel G D Kester, Dave V Serreze, Leonard D Shultz, Marieke Griffioen, Jan Wouter Drijfhout, Dale L Greiner, Bart O Roep
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49213 (2012)
Despite increasing evidence that autoreactive CD8 T-cells are involved in both the initiation of type 1 diabetes (T1D) and the destruction of beta-cells, direct evidence for their destructive role in-vivo is lacking. To address a destructive role for
Externí odkaz:
https://doaj.org/article/297b9f04854a44a28b087719b3a693fc
Autor:
Jop Jans, Sven C. J. van Dun, Renske Gorissen, Roel F. A. Pieterman, Tess S. Voskamp, Sam Schoenmakers, Hendrik Robert Taal, Wendy W. J. Unger
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSepsis is characterized by a dysregulated innate immune response. It is a leading cause of morbidity and mortality in newborns, in particular for newborns that are born premature. Although previous literature indicate that the pro-inflamm
Externí odkaz:
https://doaj.org/article/27391a2550fd43268911229e6d3399cf
Publikováno v:
Antibiotics, Vol 13, Iss 4, p 343 (2024)
Microbial biofilm formation creates a persistent and resistant environment in which microorganisms can survive, contributing to antibiotic resistance and chronic inflammatory diseases. Increasingly, biofilms are caused by multi-drug resistant microor
Externí odkaz:
https://doaj.org/article/25685a6a273a41f4a2d4d77f34e03132
Autor:
Lisa J. M. Slimmen, Vincent D. Giacalone, Craig Schofield, Hamed Horati, Badies H. A. N. Manaï, Silvia C. Estevão, Luke W. Garratt, Limin Peng, Rabindra Tirouvanziam, Hettie M. Janssens, Wendy W. J. Unger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCystic fibrosis (CF) airway disease is characterized by chronic inflammation, featuring neutrophil influx to the lumen. Airway macrophages (AMs) can promote both inflammation and resolution, and are thus critical to maintaining and restorin
Externí odkaz:
https://doaj.org/article/eae098652c744ae8b87cdc096ccd1b5e
Autor:
Hongzhen Zhu, Yang Cai, Lisa J. M. Slimmen, Adrianus C. J. M. de Bruijn, Annemarie M. C. van Rossum, Gert Folkerts, Saskia Braber, Wendy W. J. Unger
Publikováno v:
Pathogens, Vol 12, Iss 5, p 659 (2023)
The worldwide increase in the incidence of antibiotic resistance of the atypical bacterium Mycoplasma pneumoniae (MP) challenges the treatment of MP infections, especially in children. Therefore, alternative strategies for the treatment of MP infecti
Externí odkaz:
https://doaj.org/article/e8923bc1b54541e595327696645cee80
Publikováno v:
Pathogens, Vol 10, Iss 8, p 945 (2021)
Bacterial respiratory tract infections (RTIs) are a major global health burden, and the role of antigen-presenting cells (APCs) in mounting an immune response to contain and clear invading pathogens is well-described. However, most encounters between
Externí odkaz:
https://doaj.org/article/bc0d82a7e4d345d1902e6179774da2a7
Publikováno v:
Pediatric Infectious Disease Journal. 40:S26-S30
Ureaplasma species are increasingly recognized as relevant pathogens in prenatal, perinatal and postnatal morbidity. They are commonly found as commensals on the mucous membranes of the lower urogenital tract of pregnant women, but when ascending, th
Autor:
Patrick M. Meyer Sauteur, Anna Maria Christiane van Rossum, Ruben C A de Groot, Silvia Estevão, Wendy W. J. Unger, Aditya Perkasa, Emiel B. M. Spuesens, Theo Hoogenboezem, Lilly Maria Verhagen
Publikováno v:
European Respiratory Journal, 59(4):2100129. European Respiratory Society
BackgroundMycoplasma pneumoniae is the most common bacterial cause of pneumonia in children hospitalised for community-acquired pneumonia (CAP). Prevention of infection by vaccines may be an important strategy in the presence of emerging macrolide-re
Publikováno v:
Pathogens
Pathogens, Vol 10, Iss 945, p 945 (2021)
Pathogens, Vol 10, Iss 945, p 945 (2021)
Bacterial respiratory tract infections (RTIs) are a major global health burden, and the role of antigen-presenting cells (APCs) in mounting an immune response to contain and clear invading pathogens is well-described. However, most encounters between
Autor:
Wendy W. J. Unger, Paolo Paioni, Christoph Berger, Patrick M. Meyer Sauteur, Georg Staubli, Christa Relly, Lucas M. Bachmann, Johannes Trück, Annemarie M. C. van Rossum, Claudine Gysin, Michelle Seiler, Thorsten Haas
Publikováno v:
American Journal of Respiratory and Critical Care Medicine, 200(8), 1066-1069. American Thoracic Society
Mycoplasma pneumoniae (Mp) is reported to be the most common bacterial cause of community-acquired pneumonia (CAP) in hospitalized U.S. children (1). However, current diagnostic tests, including PCR of upper respiratory tract (URT) specimens and sero