Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Wendy V Ingman"'
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 9, p 328 (2024)
Background: Lactation is associated with long-term reduced risk of breast cancer. However, there is a transient increased risk of breast cancer in the 5 to 10 years postpartum and this is associated with a high incidence of metastasis and mortality.
Externí odkaz:
https://doaj.org/article/17323047e4b54a62a7753eeb018f210d
Autor:
Sarah M Bernhardt, Pallave Dasari, David Walsh, Amanda R Townsend, Timothy J Price, Wendy V Ingman
Publikováno v:
Frontiers in Oncology, Vol 6 (2016)
Clinics are increasingly adopting gene expression profiling to diagnose breast cancer subtype, providing an intrinsic, molecular portrait of the tumour. For example, the PAM50-based Prosigna test quantifies expression of 50 key genes to classify brea
Externí odkaz:
https://doaj.org/article/562affccf1e04f80bfe6e775ecd28c0a
Autor:
Helen Tower, Genevieve Dall, Ashleigh Davey, Melanie Stewart, Patrick Lanteri, Meagan Ruppert, Maria Lambouras, Ibraheem Nasir, Serene Yeow, Phillip K. Darcy, Wendy V. Ingman, Belinda Parker, Nicole M. Haynes, Kara L. Britt
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Breast cancer (BCa) incidence increases following aberrant hormone exposure, which has been linked to direct effects on estrogen receptor (ER)+ mammary epithelium. While estrogen exposure during mammary involution has been shown to drive tum
Externí odkaz:
https://doaj.org/article/49ec8610163947a8b32e9c455e48f421
Autor:
Sarah M. Bernhardt, Pallave Dasari, Danielle J. Glynn, Lucy Woolford, Lachlan M. Moldenhauer, David Walsh, Amanda R. Townsend, Timothy J. Price, Wendy V. Ingman
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background The Oncotype DX 21-gene Recurrence Score is predictive of adjuvant chemotherapy benefit for women with early-stage, estrogen receptor (ER)-positive, HER2-negative breast cancer. In premenopausal women, fluctuations in estrogen and
Externí odkaz:
https://doaj.org/article/77fcbba8fc0b44da94727e88e85ea1b2
Autor:
Xuan Sun, Sarah M. Bernhardt, Danielle J. Glynn, Leigh J. Hodson, Lucy Woolford, Andreas Evdokiou, Cong Yan, Hong Du, Sarah A. Robertson, Wendy V. Ingman
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-16 (2021)
Abstract Background Transforming growth factor beta1 (TGFB1) is a multi-functional cytokine that regulates mammary gland development and cancer progression through endocrine, paracrine and autocrine mechanisms. TGFB1 also plays roles in tumour develo
Externí odkaz:
https://doaj.org/article/a342cb32c73640b4ab603e665e81790d
Autor:
Sarah M. Bernhardt, Pallave Dasari, Joseph Wrin, Wendy Raymond, Suzanne Edwards, David Walsh, Amanda R. Townsend, Timothy J. Price, Wendy V. Ingman
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-10 (2020)
Abstract Background The Oncotype DX 21-gene Recurrence Score is a genomic-based algorithm that guides adjuvant chemotherapy treatment decisions for women with early-stage, oestrogen receptor (ER)-positive breast cancer. However, there are age-related
Externí odkaz:
https://doaj.org/article/ecd3a7d75d9a433ebff5132bbf15e62d
Autor:
Heather J. Bray, Jennifer Stone, Lillith Litchfield, Kara L. Britt, John L. Hopper, Wendy V. Ingman
Publikováno v:
Challenges, Vol 13, Iss 1, p 7 (2022)
The COVID-19 pandemic caused many scientific conferences to move online, posing a great challenge for scientific communication. This change offers potential advantages and disadvantages for inclusion, diversity, and scientific advancement. Here, we a
Externí odkaz:
https://doaj.org/article/7d0ecd60e18444ababb7ce9a57222412
Autor:
Maddison Archer, Sarah M. Bernhardt, Leigh J. Hodson, Lucy Woolford, Mark Van der Hoek, Pallave Dasari, Andreas Evdokiou, Wendy V. Ingman
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7385
CCL2 is an inflammatory cytokine that regulates macrophage activity and is implicated in increased mammographic density and early breast tumorigenesis. The role of CCL2 in mediating stromal interactions that contribute to breast tumorigenesis has yet
Autor:
Sarah M. Bernhardt, Pallave Dasari, Joseph Wrin, Wendy Raymond, Suzanne Edwards, David Walsh, Lucy Woolford, Amanda R. Townsend, Timothy J. Price, Wendy V. Ingman
Publikováno v:
The Breast. 68:240-241
Autor:
Wendy V. Ingman, Timothy J. Price, Danielle J. Glynn, Amanda R. Townsend, Sarah M. Bernhardt, Pallave Dasari
Publikováno v:
Breast Cancer Research and Treatment. 187:681-693
Protein biomarkers estrogen receptor (ER), progesterone receptor (PR), and marker of proliferation (Ki67) are routinely assessed by immunohistochemistry to guide treatment decisions for breast cancer. Now, quantification of mRNA encoding these protei