Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Wendy S. Rosebury"'
Autor:
Sandra Bak Mueller, Wendy S. Rosebury, Chetan D. Lathia, T C Major, Thomas M.A. Bocan, Helen T. Lee, Xiaokang Lu, Brian R. Krause, Catherine Dagle
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 20:70-79
Abstract —Given the significance of cholesteryl ester (CE) accumulation in macrophage foam cell formation, we hypothesized that inhibitors of acyl-CoA:cholesterol O -acyltransferase (ACAT) would produce a histologically stable lesion by limiting ma
Autor:
Wendy S. Rosebury, Alan Daugherty, Kathryn Welch, Susan L. Kuchera, Joseph A. Cornicelli, Thomas M.A. Bocan, Sandra Bak Mueller
Publikováno v:
Atherosclerosis. 136:203-216
Oxidant signalling and lipoprotein oxidation may play important roles in atherosclerotic lesion development. Given coincident localization of 15-lipoxygenase (15-LO), stereospecific products of 15-LO and epitopes of modified LDL in atherosclerotic le
Autor:
Vijaykumar M. Baragi, Wendy S. Rosebury, Ann Marie Sweet, Kathleen L. Hawkins, Mark A. Thompson, Katherine A. Toy
Publikováno v:
Connective Tissue Research. 31:153-160
This study was done to identify agents that can inhibit interleukin 1 (IL1)-induced stromelysin biosynthesis and to gain insight into the mechanism of IL1 action. For this purpose, various agents known to modulate calcium-dependent signal transductio
Publikováno v:
Cardiovascular drugs and therapy. 23(2)
Monocyte infiltration into the vessel wall, a process primarily mediated by the interaction between monocyte chemoattractant protein-1 (MCP-1) and its receptor, CCR2, is a key step in atherogenesis. Angiotensin II (Ang II) enhances this monocyte infi
Autor:
Glenn W, Gibson, Steven C, Kreuser, Janet M, Riley, Wendy S, Rosebury-Smith, Cynthia L, Courtney, Paul L, Juneau, John M, Hollembaek, Tong, Zhu, Michael D, Huband, David W, Brammer, Joan K, Brieland, Mark C, Sulavik
Publikováno v:
Comparative medicine. 57(6)
We developed a mouse model of Staphylococcus aureus infective endocarditis to evaluate the efficacy of experimental antibacterial compounds for this disease. Experimental infective endocarditis was produced in CD1 mice by intravenous challenge with a
Autor:
David W. Brammer, Jing Chen, Paul J. Kuipers, Mark D. Rekhter, Gary W. Hicks, Michael J. Ryan, Hussein Hallak, Maureen K. Anderson, Wendy S. Rosebury, Erick Kindt
Publikováno v:
Circulation research. 86(1)
Abstract —Hypercholesterolemia may render atherosclerotic plaques prone to rupture. To test this hypothesis, catheters with matrix-covered balloons were implanted into the aorta of rabbits fed standard or 0.5% cholesterol chow (n=70). In 1 month, f
Publikováno v:
Journal of veterinary internal medicine. 6(3)
A functional, insulin-secreting pancreatic (islet cell) carcinoma was diagnosed in a 17-year-old male Siamese cat. Diagnosis was made on the basis of clinical signs (i.e., seizures and stupor) that resolved temporarily after correction of hypoglycemi